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RNF157 (Ring Finger Protein 157) is a Protein Coding gene. An important paralog of this gene is MGRN1.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0016740 | transferase activity | IEA | -- |
GO:0046872 | metal ion binding | IEA | -- |
GO:0061630 | ubiquitin protein ligase activity | IBA,ISS | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | IBA | 21873635 |
GO:0005737 | cytoplasm | IBA,ISS | -- |
GO:0005769 | early endosome | IBA | 21873635 |
GO:0005886 | plasma membrane | IBA | 21873635 |
GO:0044297 | cell body | ISS | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0008333 | endosome to lysosome transport | IBA | 21873635 |
GO:0016567 | protein ubiquitination | IBA,ISS | -- |
GO:0043066 | negative regulation of apoptotic process | ISS | -- |
GO:0043951 | negative regulation of cAMP-mediated signaling | IBA | 21873635 |
GO:0045744 | negative regulation of G protein-coupled receptor signaling pathway | IBA | 21873635 |
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | RNF157 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | RNF157 30 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | RNF157 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Rnf157 30 17 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | RNF157 30 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Rnf157 30 |
|
||
Platypus (Ornithorhynchus anatinus) |
Mammalia | RNF157 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | RNF157 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | RNF157 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | rnf157 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | si:dkey-49c17.3 30 |
|
||
RNF157 31 |
|
OneToOne | |||
Fruit Fly (Drosophila melanogaster) |
Insecta | CG9941 31 |
|
OneToMany | |
Worm (Caenorhabditis elegans) |
Secernentea | C11H1.3 31 |
|
OneToMany | |
Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
SNP ID | Clinical significance and condition | Chr 17 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
728893 | Benign: not provided | 76,155,315(-) | C/A | SYNONYMOUS_VARIANT,INTRON_VARIANT | |
790187 | Benign: not provided | 76,152,455(-) | C/A | SYNONYMOUS_VARIANT | |
791204 | Benign: not provided | 76,167,779(-) | C/T | SYNONYMOUS_VARIANT | |
791506 | Benign: not provided | 76,158,415(-) | G/A | MISSENSE_VARIANT | |
rs11539879 | - | p.Gly208Arg |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv26992 | CNV | loss | 19812545 |
esv3358456 | CNV | insertion | 20981092 |
esv3641276 | CNV | loss | 21293372 |
esv3641277 | CNV | loss | 21293372 |
esv3641278 | OTHER | inversion | 21293372 |
nsv2144 | CNV | insertion | 18451855 |
nsv828104 | CNV | loss | 20364138 |
nsv833546 | CNV | loss | 17160897 |
nsv833547 | CNV | loss | 17160897 |
nsv978462 | CNV | duplication | 23825009 |
No disorders were found for RNF157 Gene.