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Aliases for RNF152 Gene
Aliases for RNF152 Gene
External Ids for RNF152 Gene
- HGNC: 26811
- NCBI Entrez Gene: 220441
- Ensembl: ENSG00000176641
- OMIM®: 616512
- UniProtKB/Swiss-Prot: Q8N8N0
Previous GeneCards Identifiers for RNF152 Gene
- GC18M057629
- GC18M057631
- GC18M059475
- GC18M056192
Summaries for RNF152 Gene
GeneCards Summary for RNF152 Gene
RNF152 (Ring Finger Protein 152) is a Protein Coding gene. Diseases associated with RNF152 include Galloway-Mowat Syndrome 5. Among its related pathways are Metabolism of proteins and mTOR signaling pathway (KEGG). Gene Ontology (GO) annotations related to this gene include ligase activity and ubiquitin-protein transferase activity. An important paralog of this gene is SPRYD4.
UniProtKB/Swiss-Prot Summary for RNF152 Gene
-
E3 ubiquitin-protein ligase mediating 'Lys-63'-linked polyubiquitination of RRAGA in response to amino acid starvation. Thereby, regulates mTORC1 signaling and plays a role in the cellular response to amino acid availability (PubMed:25936802). Also mediates 'Lys-48'-linked polyubiquitination of target proteins and their subsequent targeting to the proteasome for degradation. Induces apoptosis when overexpressed (PubMed:21203937).
Additional gene information for RNF152 Gene
- HGNC (26811)
- NCBI Entrez Gene (220441)
- Ensembl (ENSG00000176641)
- OMIM® (616512)
- UniProtKB/Swiss-Prot (Q8N8N0)
- Open Targets Platform(ENSG00000176641)
- Search for RNF152 at DataMed
- Search for RNF152 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for RNF152 Gene
Genomics for RNF152 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for RNF152 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around RNF152 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for RNF152
- Top Transcription factor binding sites by QIAGEN in the RNF152 gene promoter:
-
- Cdc5
- Gfi-1
- NF-AT
- NF-AT1
- NF-AT2
- NF-AT3
- NF-AT4
- Olf-1
- POU6F1 (c2)
- ZIC2
Genomic Locations for RNF152 Gene
Latest Assembly
- chr18:61,808,067-61,894,420
- (GRCh38/hg38)
- Size:
- 86,354 bases
- Orientation:
- Minus strand
Previous Assembly
- chr18:59,475,300-59,560,240
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 84,941 bases
- Orientation:
- Minus strand
- chr18:59,475,296-59,561,480
- (GRCh37/hg19 by Ensembl)
- Size:
- 86,185 bases
- Orientation:
- Minus strand
Genomic View for RNF152 Gene
Genes around RNF152 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 18q21.33 by HGNC
- 18q21.33 by Entrez Gene
- 18q21.33 by Ensembl
RNF152 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for RNF152 Gene
Proteins for RNF152 Gene
-
Protein details for RNF152 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8N8N0-RN152_HUMAN
- Recommended name:
- E3 ubiquitin-protein ligase RNF152
- Protein Accession:
- Q8N8N0
- B3KV99
- Q52LA4
Protein attributes for RNF152 Gene
- Size:
- 203 amino acids
- Molecular mass:
- 22357 Da
- Quaternary structure:
-
- Interacts with RRAGA (inactive GDP-bound form); stimulated by amino acid starvation (PubMed:25936802). Interacts with SEC16A (By similarity).
Protein Expression for RNF152 Gene
Post-translational modifications for RNF152 Gene
- Ubiquitinated. Autoubiquitinated in vitro, leading to its degradation by the proteasome (Probable).
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for RNF152 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- Novus Biologicals Antibodies for RNF152
- Invitrogen Antibodies for RNF152 (AFLGC-RNF152)
-
Boster Bio Antibodies for RNF152
-
Custom Antibody ServicesProSci Antibodies for RNF152
-
Santa Cruz Biotechnology (SCBT) Antibodies for RNF152
Protein products for research
-
OriGene Purified Proteins for RNF152
- Search Origene for MassSpec and Protein Over-expression Lysates for RNF152
- Origene Custom Protein Services for RNF152
- antibodies-online: Show 3 available RNF152 Proteins ranked by validation data
- Compare Top RNF152 Proteins
-
Quality Products:
Assay products for research
No data available for DME Specific Peptides for RNF152 Gene
Domains & Families for RNF152 Gene
Gene Families for RNF152 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Enzymes
- Predicted intracellular proteins
- Predicted membrane proteins
Protein Domains for RNF152 Gene
- InterPro:
- Blocks:
-
- Zn-finger, RING
- ProtoNet:
Suggested Antigen Peptide Sequences for RNF152 Gene
- GenScript: Design optimal peptide antigens:
-
- RING finger protein 152 (RN152_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q8N8N0- Family:
-
- Belongs to the RNF152 family.
Function for RNF152 Gene
Molecular function for RNF152 Gene
- UniProtKB/Swiss-Prot Function:
- E3 ubiquitin-protein ligase mediating 'Lys-63'-linked polyubiquitination of RRAGA in response to amino acid starvation. Thereby, regulates mTORC1 signaling and plays a role in the cellular response to amino acid availability (PubMed:25936802). Also mediates 'Lys-48'-linked polyubiquitination of target proteins and their subsequent targeting to the proteasome for degradation. Induces apoptosis when overexpressed (PubMed:21203937).
- UniProtKB/Swiss-Prot CatalyticActivity:
- Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.; EC=2.3.2.27; Evidence={ECO:0000269|PubMed:25936802};.
Enzyme Numbers (IUBMB) for RNF152 Gene
Phenotypes From GWAS Catalog for RNF152 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004842 | ubiquitin-protein transferase activity | IDA | 21203937 |
| GO:0005515 | protein binding | IPI | 32296183 |
| GO:0016740 | transferase activity | IEA | -- |
| GO:0031267 | small GTPase binding | IPI | 25936802 |
| GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for RNF152 Gene
- GenomeRNAi human phenotypes for RNF152:
-
- Increased gamma-H2AX phosphorylation
- no effect
- Decreased viability
- Increased shRNA abundance (Z-score > 2)
- Decreased shRNA abundance (Z-score < -2)
- Decreased number of cells in monopolar arrest with EMD534085 (a Kinesin-5 inhibitor)
- Negative genetic interaction between BLM-/- and BLM+/+
- Decreased Hepatitis C virus replication
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for RNF152 - Starting at $85 >
- * RNF152 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for RNF152
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RNF152
-
Santa Cruz Biotechnology (SCBT) CRISPR for RNF152
miRNA for RNF152 Gene
- miRTarBase miRNAs that target RNF152
-
- hsa-miR-652-3p (MIRT039527)
- hsa-miR-203b-3p (MIRT450705)
- hsa-miR-7158-3p (MIRT450706)
- hsa-miR-526b-5p (MIRT450707)
- hsa-miR-4680-5p (MIRT450708)
- hsa-miR-4635 (MIRT450709)
- hsa-miR-548g-3p (MIRT450710)
- hsa-miR-548av-3p (MIRT450711)
- hsa-miR-513a-5p (MIRT534663)
- hsa-miR-4305 (MIRT534664)
- hsa-miR-3681-3p (MIRT534665)
- hsa-miR-1288-5p (MIRT534666)
- hsa-miR-216a-3p (MIRT534667)
- hsa-miR-128-3p (MIRT534668)
- hsa-miR-5694 (MIRT534669)
- hsa-miR-101-3p (MIRT534670)
- hsa-miR-5683 (MIRT534671)
- hsa-miR-27a-3p (MIRT534672)
- hsa-miR-27b-3p (MIRT534673)
- hsa-miR-514a-3p (MIRT574069)
- hsa-miR-574-5p (MIRT574070)
- hsa-miR-1238-3p (MIRT574071)
- hsa-miR-670-3p (MIRT574072)
- hsa-miR-6867-5p (MIRT574073)
- hsa-miR-3650 (MIRT574074)
- hsa-miR-223-5p (MIRT574075)
- hsa-miR-134-3p (MIRT574076)
- hsa-miR-7114-5p (MIRT574077)
- mmu-miR-3074-2-3p (MIRT581299)
- mmu-miR-3078-5p (MIRT581300)
- mmu-miR-329-3p (MIRT581302)
- mmu-miR-362-3p (MIRT581303)
- mmu-miR-377-3p (MIRT581304)
- mmu-miR-466o-3p (MIRT591729)
- mmu-miR-466m-3p (MIRT591730)
- mmu-miR-466f-3p (MIRT591731)
- mmu-miR-466i-3p (MIRT591732)
- mmu-miR-466h-3p (MIRT591733)
- mmu-miR-3072-3p (MIRT593141)
- mmu-miR-3473a (MIRT593267)
- mmu-miR-185-5p (MIRT593268)
- mmu-miR-882 (MIRT593269)
- mmu-miR-129-5p (MIRT595481)
- mmu-miR-669o-5p (MIRT606614)
- mmu-miR-669c-5p (MIRT606615)
- hsa-miR-6873-3p (MIRT607084)
- hsa-miR-377-3p (MIRT607085)
- hsa-miR-6817-3p (MIRT607086)
- hsa-miR-7110-3p (MIRT607087)
- hsa-miR-342-3p (MIRT607088)
- hsa-miR-4789-3p (MIRT607089)
- hsa-miR-8485 (MIRT607090)
- hsa-miR-4801 (MIRT607091)
- hsa-miR-4731-3p (MIRT607092)
- hsa-miR-6833-3p (MIRT635594)
- hsa-miR-4768-5p (MIRT635595)
- hsa-miR-5009-3p (MIRT647927)
- hsa-miR-5692a (MIRT647928)
- hsa-miR-7851-3p (MIRT647929)
- hsa-miR-6788-5p (MIRT647930)
- hsa-miR-30c-2-3p (MIRT647931)
- hsa-miR-30c-1-3p (MIRT647932)
- hsa-miR-4314 (MIRT647933)
- hsa-miR-8085 (MIRT647934)
- hsa-miR-6731-5p (MIRT647935)
- hsa-miR-6878-5p (MIRT647936)
- hsa-miR-5186 (MIRT647937)
- hsa-miR-873-3p (MIRT647938)
- hsa-miR-6857-3p (MIRT647939)
- hsa-miR-6506-5p (MIRT647940)
- hsa-miR-619-5p (MIRT647941)
- hsa-miR-3192-5p (MIRT647942)
- hsa-miR-4646-5p (MIRT647943)
- hsa-miR-204-3p (MIRT647944)
- hsa-miR-3126-3p (MIRT647945)
- hsa-miR-4499 (MIRT647946)
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for RNF152
- Browse OriGene Inhibitory RNA Products For RNF152
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RNF152
Clone products for research
- Applied Biological Materials (abm): Clones for RNF152 - Starting at $45 >
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- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for RNF152
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RNF152
Cell Lines for research
-
Horizon Cell Lines for RNF152
No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for RNF152 Gene
Localization for RNF152 Gene
Subcellular locations from UniProtKB/Swiss-Prot for RNF152 Gene
- Lysosome membrane. Single-pass membrane protein.
| Compartment | Confidence |
|---|---|
| lysosome | 5 |
| plasma membrane | 3 |
| cytosol | 2 |
| extracellular | 1 |
| mitochondrion | 1 |
| nucleus | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| golgi apparatus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005764 | lysosome | IEA,IDA | 21203937 |
| GO:0005765 | lysosomal membrane | IEA,TAS | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
| GO:0031301 | integral component of organelle membrane | IMP | 25936802 |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for RNF152 Gene
Pathways & Interactions for RNF152 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Protein ubiquitination | ||
| 2 | Metabolism of proteins | ||
| 3 | mTOR signaling pathway (KEGG) | ||
Pathways by source for RNF152 Gene
4 Reactome pathways for RNF152 Gene
1 KEGG pathway for RNF152 Gene
UniProtKB/Swiss-Prot Q8N8N0-RN152_HUMAN
- Pathway: Protein modification; protein ubiquitination.
Interacting Proteins for RNF152 Gene
Selected Interacting proteins:
Q8N8N0-RN152_HUMAN
ENSP00000316628
for RNF152 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for RNF152
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000209 | protein polyubiquitination | IEA | -- |
| GO:0006915 | apoptotic process | IEA,TAS | 21203937 |
| GO:0010508 | positive regulation of autophagy | IEA,IMP | 25936802 |
| GO:0016567 | protein ubiquitination | IEA,TAS | -- |
| GO:0034198 | cellular response to amino acid starvation | IDA | 25936802 |
No data available for SIGNOR curated interactions for RNF152 Gene
Transcripts for RNF152 Gene
mRNA/cDNA for RNF152 Gene
- 1 REFSEQ mRNAs :
- 5 NCBI additional mRNA sequence :
- 5 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000312828 8745 nts (view in UCSC)
- ENST00000588064 549 nts (view in UCSC)
- ENST00000588396 457 nts (view in UCSC)
- ENST00000591306 682 nts (view in UCSC)
- ENST00000619552 792 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for RNF152 - Starting at $85 >
- * RNF152 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for RNF152
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RNF152
-
Santa Cruz Biotechnology (SCBT) CRISPR for RNF152
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for RNF152
- Browse OriGene Inhibitory RNA Products For RNF152
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RNF152
Clone products for research
- Applied Biological Materials (abm): Clones for RNF152 - Starting at $45 >
- * RNF152 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for RNF152
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RNF152
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||
| SP2: | |||||||||||
| SP3: | - |
Relevant External Links for RNF152 Gene
- GeneLoc Exon Structure for
- RNF152
Expression for RNF152 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Ovary (Reproductive System)
- Cumulus Cells Antral Follicle
-
Hair (Integumentary System)
- Bulge Stem Cells Bulge
-
Brain (Nervous System)
- Mature Choroid Plexus Cells Choroid Plexus
-
Epithelial Cells
- Mature Choroid Plexus Cells Choroid Plexus
- Adipose (Muscoskeletal System)
- NULL (Uncategorized)
-
Kidney (Urinary System)
mRNA differential expression in normal tissues according to GTEx for RNF152 Gene
This gene is overexpressed in Kidney - Cortex (x4.0).
This gene is overexpressed in Urine (69.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for RNF152 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for RNF152
SOURCE GeneReport for Unigene cluster for RNF152 Gene:
Hs.667457mRNA Expression by UniProt/SwissProt for RNF152 Gene:
Q8N8N0-RN152_HUMAN
Tissue specificity:
Widely expressed.
Evidence on tissue expression from TISSUES for RNF152 Gene
- Nervous system(4.4)
- Kidney(2.2)
Primer products for research
-
OriGene qPCR primer pairs for RNF152
Gene Expression Assays for research
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for RNF152 Gene
Orthologs for RNF152 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | RNF152 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | RNF152 31 |
|
OneToOne | |
| LOC609935 30 |
|
||||
| Oppossum (Monodelphis domestica) |
Mammalia | RNF152 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | RNF152 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Rnf152 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Rnf152 30 |
|
||
| Cow (Bos Taurus) |
Mammalia | RNF152 30 |
|
||
| Chicken (Gallus gallus) |
Aves | RNF152 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | RNF152 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | LOC100486837 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | rnf152 30 31 |
|
OneToOne | |
| Dr.20455 30 |
|
||||
| Rainbow Trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.7669 30 |
|
- Species where no ortholog for RNF152 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for RNF152 Gene
- ENSEMBL:
- Gene Tree for RNF152 (if available)
- TreeFam:
- Gene Tree for RNF152 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for RNF152: view image
Paralogs for RNF152 Gene
Paralogs for RNF152 Gene
(3) SIMAP similar genes for RNF152 Gene using alignment to 2 proteins:
- RN152_HUMAN
- K7EMG3_HUMAN
Pseudogenes.org Pseudogenes for RNF152 Gene
Variants for RNF152 Gene
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
Residual Variation Intolerance Score:
36.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.11;
38.53% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for RNF152 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- RNF152
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for RNF152 Gene
Disorders for RNF152 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| galloway-mowat syndrome 5 |
|
|
Search RNF152 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for RNF152
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for RNF152 Gene
Publications for RNF152 Gene
- The ubiquitination of rag A GTPase by RNF152 negatively regulates mTORC1 activation. (PMID: 25936802) Deng L … Wang P (Molecular cell 2015) 3 4
- RNF152, a novel lysosome localized E3 ligase with pro-apoptotic activities. (PMID: 21203937) Zhang S … Tang J (Protein & cell 2010) 3 4
- Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling. (PMID: 19240061) Trynka G … Wijmenga C (Gut 2009) 3 41
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
ExternalLinks
Products for RNF152 Gene
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- Custom Assay Services
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- Search Origene for MassSpec and Protein Over-expression Lysates for RNF152
- Origene Custom Protein Services for RNF152
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- Browse OriGene Inhibitory RNA Products For RNF152
- OriGene qPCR primer pairs for RNF152
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- Invitrogen Antibodies for RNF152 (AFLGC-RNF152)
- VectorBuilder Custom and pre-made DNA vectors for RNF152 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for RNF152 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for RNF152 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for RNF152 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for RNF152
- antibodies-online: Search results for available RNF152 related products ranked by validation data
- antibodies-online: Search results for available RNF152 related products ranked by validation data
- antibodies-online: Show 3 available RNF152 Proteins ranked by validation data
- Compare Top RNF152 Proteins
- Quality Products:
- Santa Cruz Biotechnology (SCBT) Antibodies for RNF152
- Search Santa Cruz Biotechnology (SCBT) for RNF152 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for RNF152
- Custom Antibody ServicesProSci Antibodies for RNF152
- Search for RNF152 Proteins at ProSci
- Horizon Cell Lines for RNF152
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RNF152
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RNF152
- Search GeneCopoeia for miRNA 3'UTR Target clone products for RNF152
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RNF152
- Boster Bio Antibodies for RNF152
- Browse Boster Bio ELISA Kits
Sources for RNF152 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) MedlinePlus Genetics
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNAcentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Open Targets Platform
- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB