Aliases for RNF151 Gene

Aliases for RNF151 Gene

  • Ring Finger Protein 151 2 3 5
  • RING Finger Protein 151 3 4

External Ids for RNF151 Gene

Previous GeneCards Identifiers for RNF151 Gene

  • GC16P001957
  • GC16P001958
  • GC16P001959
  • GC16P001963
  • GC16P002017
  • GC16P002019
  • GC16P001940
  • GC16P002024
  • GC16P002028
  • GC16P002047
  • GC16P002054
  • GC16P002077
  • GC16P002092
  • GC16P002113
  • GC16P001978
  • GC16P001986
  • GC16P002281
  • GC16P002317
  • GC16P002341
  • GC16P001992
  • GC16P001999
  • GC16P002008
  • GC16P002131
  • GC16P002170
  • GC16P002168
  • GC16P002200
  • GC16P002236

Summaries for RNF151 Gene

GeneCards Summary for RNF151 Gene

RNF151 (Ring Finger Protein 151) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include ubiquitin-protein transferase activity. An important paralog of this gene is RNF41.

UniProtKB/Swiss-Prot Summary for RNF151 Gene

Additional gene information for RNF151 Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for RNF151 Gene

Genomics for RNF151 Gene

GeneHancer (GH) Regulatory Elements for RNF151 Gene

Promoters and enhancers for RNF151 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16J001966 Promoter 0.5 EPDnew 500.7 +0.0 14 0.1 POLR2A ZNF121 RNF151 RPS2 SNORA78 SYNGR3 ENSG00000277602
GH16J001967 Enhancer 0.4 Ensembl 500.7 +1.5 1477 1.8 ZFHX2 ZNF18 KLF1 AGO2 EGR2 RNF151 ENSG00000255513 ENSG00000277602
GH16J002003 Promoter/Enhancer 2.7 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 11.6 +40.4 40398 7.8 ZBTB40 ZNF217 EP300 CTCF SIN3A TCF12 MYC POLR2G USF1 SP1 ZNF598 NPW TBL3 CRAMP1 ENSG00000255513 ENSG00000261505 SRRM2 ENSG00000260954 SNORA64 ENSG00000260051
GH16J002147 Promoter/Enhancer 2.7 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 11.4 +189.0 188967 17.4 FOXK2 ZBTB40 ZNF217 EP300 CTCF SIN3A NRF1 MYC TCF12 POLR2G TRAF7 SNORD60 SNHG19 ENSG00000281010 RAB26 TELO2 CRAMP1 ENSG00000260051 E4F1 ENSG00000261505
GH16J001956 Enhancer 0.3 FANTOM5 Ensembl 84 -9.9 -9922 0.2 RPL3L lnc-RPS2-1 piR-61861-010 piR-58297-192 RNF151 ENSG00000255513 BRICD5 PRSS30P lnc-MSRB1-1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around RNF151 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for RNF151

Top Transcription factor binding sites by QIAGEN in the RNF151 gene promoter:
  • AP-4
  • c-Ets-1
  • MAZR
  • NF-1
  • NF-1/L
  • NF-kappaB1
  • Pax-5
  • SRF
  • SRF (504 AA)

Genomic Locations for RNF151 Gene

Genomic Locations for RNF151 Gene
2,153 bases
Plus strand
2,153 bases
Plus strand

Genomic View for RNF151 Gene

Genes around RNF151 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RNF151 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RNF151 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNF151 Gene

Proteins for RNF151 Gene

  • Protein details for RNF151 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    RING finger protein 151
    Protein Accession:
    Secondary Accessions:
    • Q8NHS5

    Protein attributes for RNF151 Gene

    245 amino acids
    Molecular mass:
    27412 Da
    Quaternary structure:
    • Interacts with DTNBP1.

neXtProt entry for RNF151 Gene

Post-translational modifications for RNF151 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for RNF151 Gene

No data available for DME Specific Peptides for RNF151 Gene

Domains & Families for RNF151 Gene

Gene Families for RNF151 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for RNF151 Gene

Suggested Antigen Peptide Sequences for RNF151 Gene

GenScript: Design optimal peptide antigens:
  • RING finger protein 151 (RN151_HUMAN)
genes like me logo Genes that share domains with RNF151: view

No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for RNF151 Gene

Function for RNF151 Gene

Molecular function for RNF151 Gene

UniProtKB/Swiss-Prot Function:
May be involved in acrosome formation of spermatids.

Phenotypes From GWAS Catalog for RNF151 Gene

Gene Ontology (GO) - Molecular Function for RNF151 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008270 zinc ion binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with RNF151: view
genes like me logo Genes that share phenotypes with RNF151: view

Animal Model Products

CRISPR Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RNF151 Gene

Localization for RNF151 Gene

Subcellular locations from UniProtKB/Swiss-Prot for RNF151 Gene

Cytoplasm. Nucleus.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for RNF151 gene
Compartment Confidence
nucleus 4
cytosol 3
endoplasmic reticulum 1

Gene Ontology (GO) - Cellular Components for RNF151 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with RNF151: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for RNF151 Gene

Pathways & Interactions for RNF151 Gene

PathCards logo

SuperPathways for RNF151 Gene

No Data Available

Gene Ontology (GO) - Biological Process for RNF151 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007283 spermatogenesis IEA --
GO:0030154 cell differentiation IEA --
genes like me logo Genes that share ontologies with RNF151: view

No data available for Pathways by source and SIGNOR curated interactions for RNF151 Gene

Drugs & Compounds for RNF151 Gene

No Compound Related Data Available

Transcripts for RNF151 Gene

mRNA/cDNA for RNF151 Gene

4 NCBI additional mRNA sequence :
3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for RNF151 Gene

No ASD Table

Relevant External Links for RNF151 Gene

GeneLoc Exon Structure for

Expression for RNF151 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for RNF151 Gene

mRNA differential expression in normal tissues according to GTEx for RNF151 Gene

This gene is overexpressed in Testis (x51.6).

Protein differential expression in normal tissues from HIPED for RNF151 Gene

This gene is overexpressed in Monocytes (34.8) and Pancreatic juice (34.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for RNF151 Gene

Protein tissue co-expression partners for RNF151 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for RNF151

SOURCE GeneReport for Unigene cluster for RNF151 Gene:

genes like me logo Genes that share expression patterns with RNF151: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RNF151 Gene

Orthologs for RNF151 Gene

This gene was present in the common ancestor of animals.

Orthologs for RNF151 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia RNF151 31 30
  • 98.5 (n)
(Canis familiaris)
Mammalia RNF151 31 30
  • 83.67 (n)
(Bos Taurus)
Mammalia RNF151 31 30
  • 81.53 (n)
(Rattus norvegicus)
Mammalia Rnf151 30
  • 79.94 (n)
(Mus musculus)
Mammalia Rnf151 17 31 30
  • 77.83 (n)
(Monodelphis domestica)
Mammalia RNF151 31
  • 66 (a)
(Ornithorhynchus anatinus)
Mammalia RNF151 31
  • 8 (a)
(Gallus gallus)
Aves RNF151 31
  • 22 (a)
(Anolis carolinensis)
Reptilia RNF151 31
  • 16 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia rnf151 30
  • 60.52 (n)
(Danio rerio)
Actinopterygii LOC100004674 30
  • 54.69 (n)
RNF151 31
  • 35 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG9014 31
  • 15 (a)
Species where no ortholog for RNF151 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for RNF151 Gene

Gene Tree for RNF151 (if available)
Gene Tree for RNF151 (if available)
Evolutionary constrained regions (ECRs) for RNF151: view image

Paralogs for RNF151 Gene

Paralogs for RNF151 Gene

(5) SIMAP similar genes for RNF151 Gene using alignment to 2 proteins:

  • RN151_HUMAN
genes like me logo Genes that share paralogs with RNF151: view

Variants for RNF151 Gene

Additional dbSNP identifiers (rs#s) for RNF151 Gene

Structural Variations from Database of Genomic Variants (DGV) for RNF151 Gene

Variant ID Type Subtype PubMed ID
dgv336n27 CNV loss 19166990
dgv4858n54 CNV loss 21841781
esv2422427 CNV duplication 17116639
nsv1160329 CNV deletion 26073780
nsv471070 CNV gain 18288195
nsv571179 CNV loss 21841781
nsv833120 CNV loss 17160897
nsv952901 CNV deletion 24416366

Variation tolerance for RNF151 Gene

Residual Variation Intolerance Score: 88% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.18; 61.77% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for RNF151 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for RNF151 Gene

Disorders for RNF151 Gene

Additional Disease Information for RNF151

No disorders were found for RNF151 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RNF151 Gene

Publications for RNF151 Gene

  1. RNF151, a testis-specific RING finger protein, interacts with dysbindin. (PMID: 17577571) Nian H … Han C (Archives of biochemistry and biophysics 2007) 2 3 54
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 54
  3. Mining and characterization of ubiquitin E3 ligases expressed in the mouse testis. (PMID: 22992278) Hou X … Han C (BMC genomics 2012) 3 54
  4. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) Oláh J … Ovádi J (The Journal of biological chemistry 2011) 3 54
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 54

Products for RNF151 Gene

Sources for RNF151 Gene