Aliases for RNF115 Gene
External Ids for RNF115 Gene
Previous HGNC Symbols for RNF115 Gene
Previous GeneCards Identifiers for RNF115 Gene
GeneCards Summary for RNF115 Gene
RNF115 (Ring Finger Protein 115) is a Protein Coding gene. Among its related pathways are Class I MHC mediated antigen processing and presentation and Innate Immune System. Gene Ontology (GO) annotations related to this gene include ligase activity and ubiquitin protein ligase activity. An important paralog of this gene is RNF126.
UniProtKB/Swiss-Prot for RNF115 Gene
E3 ubiquitin-protein ligase that mediates E2-dependent, Lys-48- and/or Lys-63-linked polyubiquitination of substrates and may play a role in diverse biological processes. Through their polyubiquitination, may play a role in the endosomal trafficking and degradation of membrane receptors including EGFR, FLT3, MET and CXCR4.