Aliases for RND3 Gene
External Ids for RND3 Gene
Previous HGNC Symbols for RND3 Gene
Previous GeneCards Identifiers for RND3 Gene
This gene encodes a protein which is a member of the small GTPase protein superfamily. The encoded protein binds only GTP but has no GTPase activity, and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011]
GeneCards Summary for RND3 Gene
RND3 (Rho Family GTPase 3) is a Protein Coding gene. Diseases associated with RND3 include Fibroepithelial Polyp Of Urethra and Glioblastoma Multiforme. Among its related pathways are Guidance Cues and Growth Cone Motility and GPCR Pathway. Gene Ontology (GO) annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is RND2.
UniProtKB/Swiss-Prot Summary for RND3 Gene
Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.