Aliases for RNA5SP257 Gene
Subcategory (RNA class) for RNA5SP257 Gene
rRNA
Aliases for RNA5SP257 Gene
External Ids for RNA5SP257 Gene
- HGNC: 43157
- Entrez Gene: 100873511
- Ensembl: ENSG00000274467
Previous HGNC Symbols for RNA5SP257 Gene
- RN5S257
Previous GeneCards Identifiers for RNA5SP257 Gene
- GC08P020148
- GC08U901707
Summaries for RNA5SP257 Gene
GeneCards Summary for RNA5SP257 Gene
RNA5SP257 (RNA, 5S Ribosomal Pseudogene 257) is a Pseudogene, and is affiliated with the rRNA class.
fRNAdb sequence ontologies for RNA5SP257 Gene - the ORGUL cluster for this gene includes several descriptions:
-
rRNA_5S: 5S ribosomal RNA (5S rRNA) is a component of the large ribosomal subunit in both prokaryotes and eukaryotes. In eukaryotes, it is synthesised by RNA polymerase III (the other eukaryotic rRNAs are cleaved from a 45S precursor synthesised by RNA polymerase I). In Xenopus oocytes, it has been shown that fingers 4-7 of the nine-zinc finger transcription factor TFIIIA can bind to the central region of 5S RNA. Thus, in addition to positively regulating 5S rRNA transcription, TFIIIA also stabilises 5S rRNA until it is required for transcription.
-
5S ribosomal RNA: 5S ribosomal RNA (5S rRNA) is a component of the large ribosomal subunit in both prokaryotes and eukaryotes. In eukaryotes, it is synthesised by RNA polymerase III (the other eukaryotic rRNAs are cleaved from a 45S precursor synthesised by RNA polymerase I). In Xenopus oocytes, it has been shown that fingers 4-7 of the nine-zinc finger transcription factor TFIIIA can bind to the central region of 5S RNA. Thus, in addition to positively regulating 5S rRNA transcription, TFIIIA also stabilises 5S rRNA until it is required for transcription.
Additional gene information for RNA5SP257 Gene
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for RNA5SP257 Gene
Genomics for RNA5SP257 Gene
GeneHancer (GH) Regulatory Elements for RNA5SP257 Gene
Promoters and enhancers for RNA5SP257 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH08I020287 | Enhancer | 0.7 | ENCODE dbSUPER | 550.8 | -1.1 | -1051 | 2.4 | ZFHX2 MXI1 POLR2A ZIC2 SP7 EGR2 | RNA5SP257 LZTS1 LZTS1-AS1 | |
| GH08I020302 | Promoter/Enhancer | 1.4 | Ensembl ENCODE dbSUPER | 0.4 | +13.5 | 13515 | 2.6 | TFAP4 MXI1 PKNOX1 SAP130 SUZ12 ZSCAN4 SIN3A ZNF335 POLR2A VEZF1 | LZTS1 RNA5SP257 | |
| GH08I020276 | Enhancer | 1.2 | Ensembl ENCODE dbSUPER | 0.4 | -12.8 | -12821 | 1.5 | ZBTB40 ZNF766 CAVIN1 ZBTB11 USF2 HDAC8 ZNF148 MEF2D NR2C1 USF1 | LZTS1-AS1 LZTS1 INTS10 RNU6-892P RNA5SP257 | |
| GH08I020294 | Enhancer | 0.4 | dbSUPER | 0.8 | +4.8 | 4814 | 1.2 | POLR2A ZIC2 EGR2 | RNA5SP257 LZTS1 | |
| GH08I020281 | Enhancer | 0.8 | ENCODE dbSUPER | 0.4 | -7.3 | -7296 | 2.3 | ZNF189 ZEB2 OSR2 HIC1 ZNF766 POLR2A ZNF629 ZNF26 FOS RCOR1 | INTS10 RNA5SP257 LZTS1-AS1 LZTS1 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around RNA5SP257 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for RNA5SP257 Gene
Genomic Locations for RNA5SP257 Gene
- chr8:20,290,174-20,290,289
- (GRCh38/hg38)
- Size:
- 116 bases
- Orientation:
- Plus strand
Genomic View for RNA5SP257 Gene
Genes around RNA5SP257 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 8p21.3 by Ensembl
- 8p21.3 by Entrez Gene
- 8p21.3 by HGNC
RNA5SP257 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for RNA5SP257 Gene
ORGUL Member Location for RNA5SP257 Gene
Proteins for RNA5SP257 Gene
Post-translational modifications for RNA5SP257 Gene
No Post-translational modifications
Antibody Products
- Search GeneTex for Antibodies for RNA5SP257
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for RNA5SP257
- Origene Custom Protein Services for RNA5SP257
- Search GeneTex for Proteins for RNA5SP257
No data available for DME Specific Peptides for RNA5SP257 Gene
Domains & Families for RNA5SP257 Gene
Graphical View of Domain Structure for InterPro Entry
No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RNA5SP257 Gene
Function for RNA5SP257 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for RNA5SP257
-
- Search ViGene Biosciences for RNA5SP257
CRISPR Products
- Browse CRISPR knockouts for RNA5SP257
- Applied Biological Materials CRISPR for RNA5SP257
-
Vectors and viruses for KO, Activation, Repression, and more
miRNA Products
- Search ViGene Biosciences for RNA5SP257
Inhibitory RNA Products
- Search ViGene Biosciences for RNA5SP257
Clone Products
- GenScript: Custom all cDNA clones Services for RNA5SP257
- VectorBuilder custom plasmid, inducible vectors for RNA5SP257
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RNA5SP257
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for RNA5SP257
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RNA5SP257 Gene
Localization for RNA5SP257 Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for RNA5SP257 Gene
Transcripts for RNA5SP257 Gene
fRNAdb Secondary structures for RNA5SP257 Gene
mRNA/cDNA for RNA5SP257 Gene
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
- Browse CRISPR knockouts for RNA5SP257
- Applied Biological Materials CRISPR for RNA5SP257
-
Vectors and viruses for KO, Activation, Repression, and more
miRNA Products
- Search ViGene Biosciences for RNA5SP257
Inhibitory RNA Products
- Search ViGene Biosciences for RNA5SP257
Clone Products
- GenScript: Custom all cDNA clones Services for RNA5SP257
- VectorBuilder custom plasmid, inducible vectors for RNA5SP257
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RNA5SP257
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for RNA5SP257
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for RNA5SP257 Gene
NURSA nuclear receptor signaling pathways regulating expression of RNA5SP257 Gene:
RNA5SP257
No Expression Related Data Available
Primer Products
No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RNA5SP257 Gene
Orthologs for RNA5SP257 Gene
No data available for Orthologs for RNA5SP257 Gene
Paralogs for RNA5SP257 Gene
No data available for Paralogs for RNA5SP257 Gene
Variants for RNA5SP257 Gene
Additional Variant Information for RNA5SP257 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- RNA5SP257
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for RNA5SP257 Gene
Disorders for RNA5SP257 Gene
No disorders were found for RNA5SP257 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for RNA5SP257 Gene
Publications for RNA5SP257 Gene
- 5S Ribosomal RNA Database. (PMID: 11752286) Szymanski M … Barciszewski J (Nucleic acids research 2002) 1
- Crystal structure of the ribosome at 5.5 A resolution. (PMID: 11283358) Yusupov MM … Noller HF (Science (New York, N.Y.) 2001) 1
- The role of the central zinc fingers of transcription factor IIIA in binding to 5 S RNA. (PMID: 10926492) Searles MA … Klug A (Journal of molecular biology 2000) 1
Products for RNA5SP257 Gene
- Browse R&D Systems for Antibodies
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- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For RNA5SP257
- GenScript: Custom all cDNA clones Services for RNA5SP257
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- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
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- Cloud-Clone Corp. primary cells service
- Cyagen custom Knockout/knockin (KOKI) mouse models for RNA5SP257
- VectorBuilder custom plasmid, inducible vectors for RNA5SP257
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RNA5SP257
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneTex for Antibodies for RNA5SP257
- Search GeneTex for Proteins for RNA5SP257
Sources for RNA5SP257 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew