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Aliases for RNA5SP257 Gene

Subcategory (RNA class) for RNA5SP257 Gene

rRNA

Aliases for RNA5SP257 Gene

  • RNA, 5S Ribosomal Pseudogene 257 2 3 5
  • RNA, 5S Ribosomal 257 2 3
  • RN5S257 3

External Ids for RNA5SP257 Gene

ORGUL Members for RNA5SP257 Gene

Previous HGNC Symbols for RNA5SP257 Gene

  • RN5S257

Previous GeneCards Identifiers for RNA5SP257 Gene

  • GC08P020148
  • GC08U901707

Summaries for RNA5SP257 Gene

GeneCards Summary for RNA5SP257 Gene

RNA5SP257 (RNA, 5S Ribosomal Pseudogene 257) is a Pseudogene, and is affiliated with the rRNA class.

fRNAdb sequence ontologies for RNA5SP257 Gene - the ORGUL cluster for this gene includes several descriptions:

  • rRNA_5S: 5S ribosomal RNA (5S rRNA) is a component of the large ribosomal subunit in both prokaryotes and eukaryotes. In eukaryotes, it is synthesised by RNA polymerase III (the other eukaryotic rRNAs are cleaved from a 45S precursor synthesised by RNA polymerase I). In Xenopus oocytes, it has been shown that fingers 4-7 of the nine-zinc finger transcription factor TFIIIA can bind to the central region of 5S RNA. Thus, in addition to positively regulating 5S rRNA transcription, TFIIIA also stabilises 5S rRNA until it is required for transcription.

  • 5S ribosomal RNA: 5S ribosomal RNA (5S rRNA) is a component of the large ribosomal subunit in both prokaryotes and eukaryotes. In eukaryotes, it is synthesised by RNA polymerase III (the other eukaryotic rRNAs are cleaved from a 45S precursor synthesised by RNA polymerase I). In Xenopus oocytes, it has been shown that fingers 4-7 of the nine-zinc finger transcription factor TFIIIA can bind to the central region of 5S RNA. Thus, in addition to positively regulating 5S rRNA transcription, TFIIIA also stabilises 5S rRNA until it is required for transcription.

View fRNAdb secondary structures for RNA5SP257

Additional gene information for RNA5SP257 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for RNA5SP257 Gene

Genomics for RNA5SP257 Gene

GeneHancer (GH) Regulatory Elements for RNA5SP257 Gene

Promoters and enhancers for RNA5SP257 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH08I020287 Enhancer 0.7 ENCODE dbSUPER 550.8 -1.1 -1051 2.4 ZFHX2 MXI1 POLR2A ZIC2 SP7 EGR2 RNA5SP257 LZTS1 LZTS1-AS1
GH08I020302 Promoter/Enhancer 1.4 Ensembl ENCODE dbSUPER 0.4 +13.5 13515 2.6 TFAP4 MXI1 PKNOX1 SAP130 SUZ12 ZSCAN4 SIN3A ZNF335 POLR2A VEZF1 LZTS1 RNA5SP257
GH08I020276 Enhancer 1.2 Ensembl ENCODE dbSUPER 0.4 -12.8 -12821 1.5 ZBTB40 ZNF766 CAVIN1 ZBTB11 USF2 HDAC8 ZNF148 MEF2D NR2C1 USF1 LZTS1-AS1 LZTS1 INTS10 RNU6-892P RNA5SP257
GH08I020294 Enhancer 0.4 dbSUPER 0.8 +4.8 4814 1.2 POLR2A ZIC2 EGR2 RNA5SP257 LZTS1
GH08I020281 Enhancer 0.8 ENCODE dbSUPER 0.4 -7.3 -7296 2.3 ZNF189 ZEB2 OSR2 HIC1 ZNF766 POLR2A ZNF629 ZNF26 FOS RCOR1 INTS10 RNA5SP257 LZTS1-AS1 LZTS1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around RNA5SP257 on UCSC Golden Path with GeneCards custom track

Genomic Locations for RNA5SP257 Gene

Genomic Locations for RNA5SP257 Gene
chr8:20,290,174-20,290,289
(GRCh38/hg38)
Size:
116 bases
Orientation:
Plus strand

Genomic View for RNA5SP257 Gene

Genes around RNA5SP257 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RNA5SP257 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RNA5SP257 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNA5SP257 Gene

ORGUL Member Location for RNA5SP257 Gene

ORGUL Member Location for RNA5SP257 gene

Proteins for RNA5SP257 Gene

Post-translational modifications for RNA5SP257 Gene

No Post-translational modifications

No data available for DME Specific Peptides for RNA5SP257 Gene

Domains & Families for RNA5SP257 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RNA5SP257 Gene

Function for RNA5SP257 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RNA5SP257 Gene

Localization for RNA5SP257 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for RNA5SP257 Gene

Pathways & Interactions for RNA5SP257 Gene

SuperPathways for RNA5SP257 Gene

No Data Available

Interacting Proteins for RNA5SP257 Gene

Gene Ontology (GO) - Biological Process for RNA5SP257 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for RNA5SP257 Gene

Drugs & Compounds for RNA5SP257 Gene

No Compound Related Data Available

Transcripts for RNA5SP257 Gene

fRNAdb Secondary structures for RNA5SP257 Gene

  • RF00001;5S_rRNA;ABBA01021548.1/13630-13515

mRNA/cDNA for RNA5SP257 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for RNA5SP257 Gene

No ASD Table

Relevant External Links for RNA5SP257 Gene

GeneLoc Exon Structure for
RNA5SP257
ECgene alternative splicing isoforms for
RNA5SP257

Expression for RNA5SP257 Gene

NURSA nuclear receptor signaling pathways regulating expression of RNA5SP257 Gene:

RNA5SP257
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RNA5SP257 Gene

Orthologs for RNA5SP257 Gene

Evolution for RNA5SP257 Gene

ENSEMBL:
Gene Tree for RNA5SP257 (if available)
TreeFam:
Gene Tree for RNA5SP257 (if available)

No data available for Orthologs for RNA5SP257 Gene

Paralogs for RNA5SP257 Gene

No data available for Paralogs for RNA5SP257 Gene

Variants for RNA5SP257 Gene

Additional Variant Information for RNA5SP257 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
RNA5SP257

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for RNA5SP257 Gene

Disorders for RNA5SP257 Gene

No disorders were found for RNA5SP257 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for RNA5SP257 Gene

Publications for RNA5SP257 Gene

  1. 5S Ribosomal RNA Database. (PMID: 11752286) Szymanski M … Barciszewski J (Nucleic acids research 2002) 1
  2. Crystal structure of the ribosome at 5.5 A resolution. (PMID: 11283358) Yusupov MM … Noller HF (Science (New York, N.Y.) 2001) 1
  3. The role of the central zinc fingers of transcription factor IIIA in binding to 5 S RNA. (PMID: 10926492) Searles MA … Klug A (Journal of molecular biology 2000) 1

Products for RNA5SP257 Gene

Sources for RNA5SP257 Gene

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