45S ribosomal DNA (rDNA) arrays, or clusters, are present on human chromosomes 13, 14, 15, 21 and 22, designated RNR1 through RNR5, respectively. Each cluster consists of multiple 45S rDNA repeat units that vary in number among individuals and chromosomes, with total diploid copy number estimates ranging from 60 to >800 repeat units in a human genome. The 45S rDNA repeat unit e... See more...

Aliases for RNA45SN3 Gene

Subcategory (RNA class) for RNA45SN3 Gene

rRNA

Aliases for RNA45SN3 Gene

  • RNA, 45S Pre-Ribosomal N3 2 3
  • RNA, 45S Ribosomal 3

External Ids for RNA45SN3 Gene

Summaries for RNA45SN3 Gene

Entrez Gene Summary for RNA45SN3 Gene

  • 45S ribosomal DNA (rDNA) arrays, or clusters, are present on human chromosomes 13, 14, 15, 21 and 22, designated RNR1 through RNR5, respectively. Each cluster consists of multiple 45S rDNA repeat units that vary in number among individuals and chromosomes, with total diploid copy number estimates ranging from 60 to >800 repeat units in a human genome. The 45S rDNA repeat unit encodes a 45S rRNA precursor, transcribed by RNA polymerase I, which is processed to form the 18S, 5.8S and 28S rRNAs. This gene represents a copy of the 45S ribosomal RNA on chromosome 21. [provided by RefSeq, Mar 2017]

GeneCards Summary for RNA45SN3 Gene

RNA45SN3 (RNA, 45S Pre-Ribosomal N3) is an RNA Gene, and is affiliated with the rRNA class.

Additional gene information for RNA45SN3 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for RNA45SN3 Gene

Genomics for RNA45SN3 Gene

Genomic Locations for RNA45SN3 Gene

Genomic Locations for RNA45SN3 Gene
chr21:-
(GRCh38/hg38)
Orientation:
Unknown strand

Genomic View for RNA45SN3 Gene


Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for RNA45SN3 Gene

No data available for GeneHancer (GH) Regulatory Elements for RNA45SN3 Gene

Proteins for RNA45SN3 Gene

Post-translational modifications for RNA45SN3 Gene

No Post-translational modifications

No data available for DME Specific Peptides for RNA45SN3 Gene

Domains & Families for RNA45SN3 Gene

Gene Families for RNA45SN3 Gene

genes like me logo Genes that share domains with RNA45SN3: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for RNA45SN3 Gene

Function for RNA45SN3 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RNA45SN3 Gene

Localization for RNA45SN3 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for RNA45SN3 Gene

Pathways & Interactions for RNA45SN3 Gene

PathCards logo

SuperPathways for RNA45SN3 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for RNA45SN3 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for RNA45SN3 Gene

Drugs & Compounds for RNA45SN3 Gene

No Compound Related Data Available

Transcripts for RNA45SN3 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for RNA45SN3 Gene

No ASD Table

No data available for mRNA/cDNA for RNA45SN3 Gene

Expression for RNA45SN3 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RNA45SN3 Gene

Orthologs for RNA45SN3 Gene

No data available for Orthologs and Evolution for RNA45SN3 Gene

Paralogs for RNA45SN3 Gene

No data available for Paralogs for RNA45SN3 Gene

Variants for RNA45SN3 Gene

Additional dbSNP identifiers (rs#s) for RNA45SN3 Gene

Additional Variant Information for RNA45SN3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
RNA45SN3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for RNA45SN3 Gene

Disorders for RNA45SN3 Gene

Additional Disease Information for RNA45SN3

No disorders were found for RNA45SN3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RNA45SN3 Gene

Publications for RNA45SN3 Gene

  1. The Epigenetic Pathways to Ribosomal DNA Silencing. (PMID: 27250769) Srivastava R … Ahn SH (Microbiology and molecular biology reviews : MMBR 2016) 3 54
  2. A Portrait of Ribosomal DNA Contacts with Hi-C Reveals 5S and 45S rDNA Anchoring Points in the Folded Human Genome. (PMID: 27797956) Yu S … Lemos B (Genome biology and evolution 2016) 3 54
  3. Nucleolar organizer regions: genomic 'dark matter' requiring illumination. (PMID: 27474438) McStay B (Genes & development 2016) 3 54
  4. Concerted copy number variation balances ribosomal DNA dosage in human and mouse genomes. (PMID: 25583482) Gibbons JG … Lemos B (Proceedings of the National Academy of Sciences of the United States of America 2015) 3 54
  5. An overview of pre-ribosomal RNA processing in eukaryotes. (PMID: 25346433) Henras AK … Gleizes PE (Wiley interdisciplinary reviews. RNA 2015) 3 54

No data available for Mastermind for RNA45SN3 Gene

Products for RNA45SN3 Gene

Sources for RNA45SN3 Gene