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Aliases for RN7SL217P Gene

Subcategory (RNA class) for RN7SL217P Gene


Aliases for RN7SL217P Gene

  • RNA, 7SL, Cytoplasmic 217, Pseudogene 2 3 5

External Ids for RN7SL217P Gene

Previous GeneCards Identifiers for RN7SL217P Gene

  • GC03M049907
  • GC03M049909

Summaries for RN7SL217P Gene

GeneCards Summary for RN7SL217P Gene

RN7SL217P (RNA, 7SL, Cytoplasmic 217, Pseudogene) is a Pseudogene, and is affiliated with the SRP RNA class.

fRNAdb sequence ontologies for RN7SL217P Gene

  • Metazoan signal recognition particle RNA: The signal recognition particle (SRP) is a universally conserved ribonucleoprotein. It is involved in the co-translational targeting of proteins to membranes. The eukaryotic SRP consists of a 300-nucleotide 7S RNA and six proteins: SRPs 72, 68, 54, 19, 14, and 9. Archaeal SRP consists of a 7S RNA and homologues of the eukaryotic SRP19 and SRP54 proteins. Eukaryotic and archaeal 7S RNAs have very similar secondary structures, as represented by this family. Eight helical elements fold into the Alu and S domains, separated by a long linker region [1,2]. The Alu domain is thought to mediate the peptide chain elongation retardation function of the SRP [1]. The universally conserved helix which interacts with the SRP54 M domain mediates signal sequence recognition [2,3]. In eukaryotes and archaea, the SRP19-helix 6 complex is thought to be involved in SRP assembly and stabilises helix 8 for SRP54 binding [1]. The Signal Recognition Particle Database (SRPDB) [4] provides compilations of SRP components, with phylogenetic data and structural illustrations. Many sequences below the threshold for this family are clearly closely related, but are most likely to be SRP RNA derived pseudogenes. The human genome in particular is known to contain a large amount of SRP RNA related sequence, including Alu repeats. While the threshold of this family is set high so as to minimise the number of hits to such regions, it is likely that some remain.

Additional gene information for RN7SL217P Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for RN7SL217P Gene

Genomics for RN7SL217P Gene

GeneHancer (GH) Regulatory Elements for RN7SL217P Gene

Promoters and enhancers for RN7SL217P Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH03I049868 Promoter/Enhancer 1.4 EPDnew Ensembl ENCODE 0.4 -5.7 -5736 2 MXI1 USF1 ZNF777 BACH1 ZIC2 BCL11B HIC1 ZNF335 GLIS2 POLR2A CAMKV RBM6 ENSG00000230698 ENSG00000228008 MST1R IP6K1 PHF5EP RN7SL217P GC03P049762 GC03P049763
GH03I049867 Enhancer 0.6 ENCODE 0.8 -4.3 -4313 0.2 AFF1 SAP130 ZNF133 ARID4B NCOA1 SIN3A MIER2 REST ZSCAN9 RARA ENSG00000230698 ENSG00000228008 MST1R IP6K1 PHF5EP CAMKV RN7SL217P GC03P049762 GC03P049763 GC03P049421
GH03I049869 Enhancer 0.6 ENCODE 0.8 -4.6 -4563 0.2 AFF1 SAP130 ZNF133 ARID4B NCOA1 REST ZSCAN9 POLR2A ZNF143 CAMKV ENSG00000230698 ENSG00000228008 MST1R IP6K1 PHF5EP RN7SL217P GC03P049762 GC03P049763 GC03P049421
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around RN7SL217P on UCSC Golden Path with GeneCards custom track

Genomic Locations for RN7SL217P Gene

Genomic Locations for RN7SL217P Gene
286 bases
Minus strand

Genomic View for RN7SL217P Gene

Genes around RN7SL217P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RN7SL217P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RN7SL217P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RN7SL217P Gene

ORGUL Member Location for RN7SL217P Gene

ORGUL Member Location for RN7SL217P gene

Proteins for RN7SL217P Gene

Post-translational modifications for RN7SL217P Gene

No Post-translational modifications

No data available for DME Specific Peptides for RN7SL217P Gene

Domains & Families for RN7SL217P Gene

Gene Families for RN7SL217P Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RN7SL217P: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RN7SL217P Gene

Function for RN7SL217P Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RN7SL217P Gene

Localization for RN7SL217P Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for RN7SL217P Gene

Pathways & Interactions for RN7SL217P Gene

SuperPathways for RN7SL217P Gene

No Data Available

Interacting Proteins for RN7SL217P Gene

Gene Ontology (GO) - Biological Process for RN7SL217P Gene


No data available for Pathways by source and SIGNOR curated interactions for RN7SL217P Gene

Drugs & Compounds for RN7SL217P Gene

No Compound Related Data Available

Transcripts for RN7SL217P Gene

mRNA/cDNA for RN7SL217P Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RN7SL217P Gene

No ASD Table

Relevant External Links for RN7SL217P Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RN7SL217P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for RN7SL217P Gene

NURSA nuclear receptor signaling pathways regulating expression of RN7SL217P Gene:

genes like me logo Genes that share expression patterns with RN7SL217P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RN7SL217P Gene

Orthologs for RN7SL217P Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for RN7SL217P Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia Metazoa_SRP 34
  • 100 (a)
Species where no ortholog for RN7SL217P was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for RN7SL217P Gene

Gene Tree for RN7SL217P (if available)
Gene Tree for RN7SL217P (if available)

Paralogs for RN7SL217P Gene

No data available for Paralogs for RN7SL217P Gene

Variants for RN7SL217P Gene

Additional Variant Information for RN7SL217P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for RN7SL217P Gene

Disorders for RN7SL217P Gene

No disorders were found for RN7SL217P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for RN7SL217P Gene

Publications for RN7SL217P Gene

  1. SRPDB: Signal Recognition Particle Database. (PMID: 12520023) Rosenblad MA … Samuelsson T (Nucleic acids research 2003) 1
  2. Towards the structure of the mammalian signal recognition particle. (PMID: 11839493) Wild K … Cusack S (Current opinion in structural biology 2002) 1
  3. Prediction of signal recognition particle RNA genes. (PMID: 12140321) Regalia M … Samuelsson T (Nucleic acids research 2002) 1
  4. Structural and energetic analysis of RNA recognition by a universally conserved protein from the signal recognition particle. (PMID: 11243816) Batey RT … Doudna JA (Journal of molecular biology 2001) 1
  5. Crystal structure of the ribonucleoprotein core of the signal recognition particle. (PMID: 10678824) Batey RT … Doudna JA (Science (New York, N.Y.) 2000) 1

Products for RN7SL217P Gene

Sources for RN7SL217P Gene

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