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Aliases for RN7SL2 Gene

Subcategory (RNA class) for RN7SL2 Gene


Quality Score for this RNA gene is


Aliases for RN7SL2 Gene

  • RNA, 7SL, Cytoplasmic 2 2 3 5
  • 7L30.1 3
  • RNSRP2 3
  • 7SL1c 3
  • 7L1C 3

External Ids for RN7SL2 Gene

ORGUL Members for RN7SL2 Gene

Previous GeneCards Identifiers for RN7SL2 Gene

  • GC00U913091
  • GC14U900448
  • GC14M049403
  • GC14M050329
  • GC14M049863

Summaries for RN7SL2 Gene

Entrez Gene Summary for RN7SL2 Gene

  • The signal recognition particle (SRP) is a cytoplasmic ribonucleoprotein complex that mediates cotranslational insertion of secretory proteins into the lumen of the endoplasmic reticulum. The SRP consists of 6 polypeptides (e.g., SRP19; MIM 182175) and a 7SL RNA molecule, such as RN7SL2, that is partially homologous to Alu DNA (Ullu and Weiner, 1984 [PubMed 6084597]).[supplied by OMIM, Jul 2008]

GeneCards Summary for RN7SL2 Gene

RN7SL2 (RNA, 7SL, Cytoplasmic 2) is an RNA Gene, and is affiliated with the SRP RNA class.

Additional gene information for RN7SL2 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RN7SL2 Gene

Genomics for RN7SL2 Gene

GeneHancer (GH) Regulatory Elements for RN7SL2 Gene

Promoters and enhancers for RN7SL2 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14I049860 Promoter/Enhancer 2.1 FANTOM5 Ensembl ENCODE dbSUPER 550.8 +0.6 555 4.6 CLOCK MLX FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 ZNF143 ENSG00000278002 GC14M049865 GC14M049869 GC14P049865 PIR56593 RN7SL2 KLHDC1 NEMF MAP4K5 KLHDC2
GH14I049857 Enhancer 1 Ensembl ENCODE dbSUPER 0.8 +4.7 4700 1.6 MEIS2 SRF JUNB BATF MITF POLR2A IKZF1 ZFP36 RUNX3 IKZF2 VCPKMT RNU6-189P ENSG00000282885 GC14M049855 GC14M049865 RN7SL3 RN7SL2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around RN7SL2 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the RN7SL2 gene promoter:

Genomic Locations for RN7SL2 Gene

Genomic Locations for RN7SL2 Gene
300 bases
Minus strand

Genomic View for RN7SL2 Gene

Genes around RN7SL2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RN7SL2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RN7SL2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RN7SL2 Gene

Proteins for RN7SL2 Gene

Post-translational modifications for RN7SL2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for RN7SL2 Gene

Domains & Families for RN7SL2 Gene

Gene Families for RN7SL2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RN7SL2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RN7SL2 Gene

Function for RN7SL2 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RN7SL2 Gene

Localization for RN7SL2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for RN7SL2 Gene

Pathways & Interactions for RN7SL2 Gene

SuperPathways for RN7SL2 Gene

No Data Available

Interacting Proteins for RN7SL2 Gene

Gene Ontology (GO) - Biological Process for RN7SL2 Gene


No data available for Pathways by source and SIGNOR curated interactions for RN7SL2 Gene

Drugs & Compounds for RN7SL2 Gene

No Compound Related Data Available

Transcripts for RN7SL2 Gene

mRNA/cDNA for RN7SL2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for RN7SL2 Gene

No ASD Table

Relevant External Links for RN7SL2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RN7SL2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for RN7SL2 Gene

mRNA differential expression in normal tissues according to GTEx for RN7SL2 Gene

This gene is overexpressed in Whole Blood (x8.7).

NURSA nuclear receptor signaling pathways regulating expression of RN7SL2 Gene:

genes like me logo Genes that share expression patterns with RN7SL2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RN7SL2 Gene

Orthologs for RN7SL2 Gene

Evolution for RN7SL2 Gene

Gene Tree for RN7SL2 (if available)
Gene Tree for RN7SL2 (if available)

No data available for Orthologs for RN7SL2 Gene

Paralogs for RN7SL2 Gene

No data available for Paralogs for RN7SL2 Gene

Variants for RN7SL2 Gene

Sequence variations from dbSNP and Humsavar for RN7SL2 Gene

SNP ID Clin Chr 14 pos Variation AA Info Type
rs1000989324 -- 49,864,437(-) TT/T upstream_transcript_variant
rs1002349233 -- 49,863,542(-) G/A upstream_transcript_variant
rs1003216556 -- 49,864,724(-) A/G upstream_transcript_variant
rs1003450081 -- 49,862,557(-) GGGG/GGGGG non_coding_transcript_variant
rs1004044831 -- 49,864,666(-) C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for RN7SL2 Gene

Variant ID Type Subtype PubMed ID
esv28926 CNV gain+loss 19812545

Additional Variant Information for RN7SL2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for RN7SL2 Gene

Disorders for RN7SL2 Gene

Additional Disease Information for RN7SL2

No disorders were found for RN7SL2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RN7SL2 Gene

Publications for RN7SL2 Gene

  1. Kinship in the SRP RNA family. (PMID: 19838050) Rosenblad MA … Zwieb C (RNA biology 2009) 3 58
  2. The tmRDB and SRPDB resources. (PMID: 16381838) Andersen ES … Zwieb C (Nucleic acids research 2006) 3 58
  3. Human genes and pseudogenes for the 7SL RNA component of signal recognition particle. (PMID: 6084597) Ullu E … Weiner AM (The EMBO journal 1984) 3 58
  4. RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination. (PMID: 29117863) Choudhury NR … Michlewski G (BMC biology 2017) 3

Products for RN7SL2 Gene

Sources for RN7SL2 Gene

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