Aliases for RN7SKP279 Gene
Subcategory (RNA class) for RN7SKP279 Gene
7SK RNA
External Ids for RN7SKP279 Gene
- HGNC: 46003
- Entrez Gene: 106480479
- Ensembl: ENSG00000223315
ORGUL Members for RN7SKP279 Gene
Previous GeneCards Identifiers for RN7SKP279 Gene
- GC11P127279
Summaries for RN7SKP279 Gene
GeneCards Summary for RN7SKP279 Gene
RN7SKP279 (RNA, 7SK Small Nuclear Pseudogene 279) is a Pseudogene, and is affiliated with the 7SK RNA class.
fRNAdb sequence ontologies for RN7SKP279 Gene
-
7SK RNA: 7SK was discovered as an abundant small nuclear RNA in the mid-70s but a possible function has only recently been suggested [1]. Two independent studies have found that 7SK RNA binds the CDK9/cyclin T complex (known as elongation factor P-TEFb). P-TEFb activates transcription by phosphorylating the C-terminal domain of RNA polymerase II. This process is negatively regulated by the 7SK RNP. The secondary structure of 7SK RNA shown here was proposed by Wasserman and Steitz on the basis of chemical modification and enzymatic cleavage experiments [2]. This family contains a number of annotated pseudogenes and 7SK derived repeats. The threshold is artificially high to minimise the pseudogene count.
Additional gene information for RN7SKP279 Gene
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for RN7SKP279 Gene
Genomics for RN7SKP279 Gene
Regulatory Element Products
Genomic Locations for RN7SKP279 Gene
Genomic Locations for RN7SKP279 Gene
- chr11:127,407,851-127,408,148
- (GRCh38/hg38)
- Size:
- 298 bases
- Orientation:
- Plus strand
- chr11:127,277,746-127,278,043
- (GRCh37/hg19)
- Size:
- 298 bases
- Orientation:
- Plus strand
Genomic View for RN7SKP279 Gene
Genes around RN7SKP279 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11q24.2 by Entrez Gene
- 11q24.2 by HGNC
- 11q24.2 by Ensembl
RN7SKP279 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for RN7SKP279 Gene
No data available for GeneHancer (GH) Regulatory Elements for RN7SKP279 Gene
Proteins for RN7SKP279 Gene
Post-translational modifications for RN7SKP279 Gene
No Post-translational modifications
Antibody Products
- Search GeneTex for Antibodies for RN7SKP279
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for RN7SKP279
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- Search GeneTex for Proteins for RN7SKP279
No data available for DME Specific Peptides for RN7SKP279 Gene
Domains & Families for RN7SKP279 Gene
Graphical View of Domain Structure for InterPro Entry
No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RN7SKP279 Gene
Function for RN7SKP279 Gene
Phenotypes From GWAS Catalog for RN7SKP279 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for RN7SKP279
-
miRNA Products
Inhibitory RNA Products
Clone Products
- GenScript: Custom all cDNA clones Services for RN7SKP279
- VectorBuilder custom plasmid, inducible vectors for RN7SKP279
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RN7SKP279
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RN7SKP279 Gene
Localization for RN7SKP279 Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for RN7SKP279 Gene
Transcripts for RN7SKP279 Gene
mRNA/cDNA for RN7SKP279 Gene
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000411383 298 bps (uc058jai.1)
CRISPR Products
- Browse CRISPR knockouts for RN7SKP279
miRNA Products
Inhibitory RNA Products
Clone Products
- GenScript: Custom all cDNA clones Services for RN7SKP279
- VectorBuilder custom plasmid, inducible vectors for RN7SKP279
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RN7SKP279
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Expression for RN7SKP279 Gene
NURSA nuclear receptor signaling pathways regulating expression of RN7SKP279 Gene:
RN7SKP279
Primer Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RN7SKP279 Gene
Orthologs for RN7SKP279 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | 7SK 34 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | 7SK 34 |
|
OneToOne |
- Species where no ortholog for RN7SKP279 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- cow (Bos Taurus)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- mouse (Mus musculus)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for RN7SKP279 Gene
No data available for Paralogs for RN7SKP279 Gene
Variants for RN7SKP279 Gene
Additional Variant Information for RN7SKP279 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- RN7SKP279
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for RN7SKP279 Gene
Disorders for RN7SKP279 Gene
No disorders were found for RN7SKP279 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for RN7SKP279 Gene
Publications for RN7SKP279 Gene
No publications were found for RN7SKP279 Gene.
Products for RN7SKP279 Gene
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- Cyagen custom Knockout/knockin (KOKI) mouse models for RN7SKP279
- VectorBuilder custom plasmid, inducible vectors for RN7SKP279
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RN7SKP279
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for knockout CRISPR/Cas9 clones, lentivirus, and/or AAV products for RN7SKP279
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Sources for RN7SKP279 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
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- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt