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Aliases for RN7SK Gene
Subcategory (RNA class) for RN7SK Gene
snRNA
Number of RNA Genes sources:
4 / 17
Aliases for RN7SK Gene
External Ids for RN7SK Gene
- HGNC: 10037
- Entrez Gene: 125050
- Ensembl: ENSG00000283293
- OMIM: 606515
Previous GeneCards Identifiers for RN7SK Gene
- GC06U990106
- GC06P052907
- GC06P052968
- GC06P052860
- GC06P052691
Summaries for RN7SK Gene
GeneCards Summary for RN7SK Gene
RN7SK (RNA Component Of 7SK Nuclear Ribonucleoprotein) is an RNA Gene, and is affiliated with the snRNA class. Diseases associated with RN7SK include Acquired Immunodeficiency Syndrome and Gastric Cancer.
Rfam classification for RN7SK Gene
-
7SK RNA
No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , PharmGKB "VIP" Summary and piRNA Summary for RN7SK Gene
Genomics for RN7SK Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for RN7SK Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH06J052992 | Promoter/Enhancer | 2.4 | EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER | 600.7 | -0.7 | -714 | 4.6 | HNRNPL CREB1 GATAD2A CTCF PRDM10 ZNF629 LEF1 IKZF1 NFKBIZ KDM1A | ENSG00000202198 GSTA4 MN298307 RN7SK X05490 EFHC1 MCM3 CILK1 GSTA3 RF00019-091 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around RN7SK on the GeneHancer Hub at the UCSC Golden Path
- Top Transcription factor binding sites by QIAGEN in the RN7SK gene promoter:
-
- HEN1
- Oct-B1
- oct-B2
- oct-B3
- POU2F1
- POU2F1a
- POU2F2
- POU2F2 (Oct-2.1)
- POU2F2B
- POU2F2C
Genomic Locations for RN7SK Gene
Genomic Locations for RN7SK Gene
- chr6:52,995,615-52,995,951
- (GRCh38/hg38)
- Size:
- 337 bases
- Orientation:
- Plus strand
- chr6:52,860,418-52,860,749
- (GRCh37/hg19)
- Size:
- 332 bases
- Orientation:
- Plus strand
Genomic View for RN7SK Gene
Genes around RN7SK on UCSC Golden Path with GeneCards custom track
RN7SK in the GeneCards ncRNA compendium hub on the UCSC Golden Path
- Cytogenetic band:
-
- 6p12.2 by HGNC
- 6p12.2 by Entrez Gene
- 6p12.2 by Ensembl
RN7SK Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for RN7SK Gene
Proteins for RN7SK Gene
Post-translational modifications for RN7SK Gene
No Post-translational modifications
Antibody Products
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for RN7SK
- Origene Custom Protein Services for RN7SK
No data available for DME Specific Peptides for RN7SK Gene
Domains & Families for RN7SK Gene
Gene Families for RN7SK Gene
No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for RN7SK Gene
Function for RN7SK Gene
Molecular function for RN7SK Gene
- GENATLAS Biochemistry:
- small nuclear RNA,7SK
Phenotypes From GWAS Catalog for RN7SK Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for RN7SK - Select products 50% OFF >
- * RN7SK CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for RN7SK
miRNA for RN7SK Gene
- miRTarBase miRNAs that target RN7SK
miRNA Products
Inhibitory RNA Products
Clone Products
- Applied Biological Materials (abm): Clones for RN7SK - Select products 50% OFF >
- * RN7SK as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Addgene plasmids for RN7SK
No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for RN7SK Gene
Localization for RN7SK Gene
| Compartment | Confidence |
|---|---|
| nucleus | 3 |
| plasma membrane | 1 |
| extracellular | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| cytosol | 1 |
| lysosome | 1 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for RN7SK Gene
Transcripts for RN7SK Gene
Non-coding RNA (ncRNA) Transcripts from RNAcentral for RN7SK Gene
| RNAcentral Transcript ID | Subcategory | Length (nts) | # of Sources | Source Identifiers and Annotations |
|---|---|---|---|---|
| URS0000734D8F_9606 | snRNA | 332 | 4 |
HGNC: 10037, RefSeq: NR_001445, LNCipedia: lnc-FBXO9-1:2, NONCODE: NONHSAT113149.2, |
| URS0000AAF09C_9606 | snRNA | 328 | 1 |
Ensembl: ENST00000636484 (view in UCSC) , |
| URS0000D56E44_9606 | lncRNA | 336 | 1 |
LNCipedia: lnc-FBXO9-1:3, |
| URS0000D5A07E_9606 | lncRNA | 333 | 1 |
LNCipedia: lnc-FBXO9-1:1, |
| URS000065EDD0_9606 | snRNA | 330 | 1 |
Rfam: RF00100, |
RN7SK in the GeneCards ncRNA compendium hub on the UCSC Golden Path
Additional transcripts not in RNAcentral for RN7SK Gene
- 1 NCBI additional mRNA sequence :
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for RN7SK - Select products 50% OFF >
- * RN7SK CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for RN7SK
miRNA Products
Inhibitory RNA Products
Clone Products
- Applied Biological Materials (abm): Clones for RN7SK - Select products 50% OFF >
- * RN7SK as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Addgene plasmids for RN7SK
Relevant External Links for RN7SK Gene
- GeneLoc Exon Structure for
- RN7SK
Expression for RN7SK Gene
mRNA differential expression in normal tissues according to GTEx for RN7SK Gene
This gene is overexpressed in Kidney - Cortex (x5.1).
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for RN7SK
Primer Products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RN7SK Gene
Orthologs for RN7SK Gene
No data available for Orthologs for RN7SK Gene
Paralogs for RN7SK Gene
No data available for Paralogs for RN7SK Gene
Variants for RN7SK Gene
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2759430 | CNV | loss | 17122850 |
Additional Variant Information for RN7SK Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- RN7SK
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for RN7SK Gene
Disorders for RN7SK Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| acquired immunodeficiency syndrome |
|
|
| gastric cancer |
|
|
| isolated growth hormone deficiency, type ia |
|
|
Search RN7SK in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for RN7SK
No data available for UniProtKB/Swiss-Prot and Genatlas for RN7SK Gene
Publications for RN7SK Gene
- Structural basis for recognition of human 7SK long noncoding RNA by the La-related protein Larp7. (PMID: 29946027) Eichhorn CD … Feigon J (Proceedings of the National Academy of Sciences of the United States of America 2018) 2 3
- 7SK RNA, a non-coding RNA regulating P-TEFb, a general transcription factor. (PMID: 19246988) Diribarne G … Bensaude O (RNA biology 2009) 2 3
- Regulation of two key nuclear enzymatic activities by the 7SK small nuclear RNA. (PMID: 17381310) He WJ … Zhou Q (Cold Spring Harbor symposia on quantitative biology 2006) 3 23
- Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4. (PMID: 16109377) Yang Z … Zhou Q (Molecular cell 2005) 3 23
- Phosphorylated positive transcription elongation factor b (P-TEFb) is tagged for inhibition through association with 7SK snRNA. (PMID: 14627702) Chen R … Zhou Q (The Journal of biological chemistry 2004) 3 23
ExternalLinks
Products for RN7SK Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for RN7SK
- Origene Custom Protein Services for RN7SK
- Browse OriGene Inhibitory RNA Products For RN7SK
- Browse OriGene qPCR primer pairs and template standards
- OriGene CRISPR knockouts for RN7SK
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For RN7SK
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Addgene plasmids for RN7SK
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for knockout CRISPR/Cas9 clones, lentivirus, and/or AAV products for RN7SK
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles, and/or promoter clone products for RN7SK
- Search GeneCopoeia for miRNA 3'UTR Target clone products for RN7SK
- Search GeneCopoeia for shRNA, lentivirus, and/or AAV clone products for RN7SK
Sources for RN7SK Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB