Aliases for RN7SK Gene

Subcategory (RNA class) for RN7SK Gene

snRNA

Number of RNA Genes sources:

4 / 17

Aliases for RN7SK Gene

  • RNA Component Of 7SK Nuclear Ribonucleoprotein 2 3 5
  • RNA, 7SK Small Nuclear 2 3
  • RNA, 7SK, Nuclear 2 3
  • RN7SK 2 5
  • 7SK 2 3
  • 7SK Small Nuclear RNA 3
  • NONHSAG043942.2 91
  • Lnc-FBXO9-1 165
  • RF00100 168
  • 4WKR_C 167
  • 4WKR_D 167

External Ids for RN7SK Gene

Previous GeneCards Identifiers for RN7SK Gene

  • GC06U990106
  • GC06P052907
  • GC06P052968
  • GC06P052860
  • GC06P052691

Summaries for RN7SK Gene

GeneCards Summary for RN7SK Gene

RN7SK (RNA Component Of 7SK Nuclear Ribonucleoprotein) is an RNA Gene, and is affiliated with the snRNA class. Diseases associated with RN7SK include Acquired Immunodeficiency Syndrome and Gastric Cancer.

Gene Wiki entry for RN7SK Gene

Rfam classification for RN7SK Gene

Additional gene information for RN7SK Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , PharmGKB "VIP" Summary and piRNA Summary for RN7SK Gene

Genomics for RN7SK Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for RN7SK Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH06J052992 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 600.7 -0.7 -714 4.6 HNRNPL CREB1 GATAD2A CTCF PRDM10 ZNF629 LEF1 IKZF1 NFKBIZ KDM1A ENSG00000202198 GSTA4 MN298307 RN7SK X05490 EFHC1 MCM3 CILK1 GSTA3 RF00019-091
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around RN7SK on the GeneHancer Hub at the UCSC Golden Path

Top Transcription factor binding sites by QIAGEN in the RN7SK gene promoter:
  • HEN1
  • Oct-B1
  • oct-B2
  • oct-B3
  • POU2F1
  • POU2F1a
  • POU2F2
  • POU2F2 (Oct-2.1)
  • POU2F2B
  • POU2F2C

Genomic Locations for RN7SK Gene

Genomic Locations for RN7SK Gene
chr6:52,995,615-52,995,951
(GRCh38/hg38)
Size:
337 bases
Orientation:
Plus strand
chr6:52,860,418-52,860,749
(GRCh37/hg19)
Size:
332 bases
Orientation:
Plus strand

Genomic View for RN7SK Gene

Genes around RN7SK on UCSC Golden Path with GeneCards custom track
RN7SK in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
RN7SK Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RN7SK Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RN7SK Gene

Proteins for RN7SK Gene

No data available for DME Specific Peptides for RN7SK Gene

Domains & Families for RN7SK Gene

genes like me logo Genes that share domains with RN7SK: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for RN7SK Gene

Function for RN7SK Gene

Molecular function for RN7SK Gene

GENATLAS Biochemistry:
small nuclear RNA,7SK

Phenotypes From GWAS Catalog for RN7SK Gene

Animal Model Products

CRISPR Products

miRNA for RN7SK Gene

miRTarBase miRNAs that target RN7SK

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for RN7SK Gene

Localization for RN7SK Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for RN7SK gene
Compartment Confidence
nucleus 3
plasma membrane 1
extracellular 1
cytoskeleton 1
mitochondrion 1
endoplasmic reticulum 1
endosome 1
cytosol 1
lysosome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for RN7SK Gene

Pathways & Interactions for RN7SK Gene

PathCards logo

SuperPathways for RN7SK Gene

No Data Available

Gene Ontology (GO) - Biological Process for RN7SK Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for RN7SK Gene

Drugs & Compounds for RN7SK Gene

No Compound Related Data Available

Transcripts for RN7SK Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for RN7SK Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS0000734D8F_9606 snRNA 332 4

HGNC: 10037,

RefSeq: NR_001445,

LNCipedia: lnc-FBXO9-1:2,

NONCODE: NONHSAT113149.2,

URS0000AAF09C_9606 snRNA 328 1

Ensembl: ENST00000636484 (view in UCSC) ,

URS0000D56E44_9606 lncRNA 336 1

LNCipedia: lnc-FBXO9-1:3,

URS0000D5A07E_9606 lncRNA 333 1

LNCipedia: lnc-FBXO9-1:1,

URS000065EDD0_9606 snRNA 330 1

Rfam: RF00100,

RN7SK in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for RN7SK Gene

1 NCBI additional mRNA sequence :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for RN7SK Gene

No ASD Table

Relevant External Links for RN7SK Gene

GeneLoc Exon Structure for
RN7SK

Expression for RN7SK Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for RN7SK Gene

mRNA differential expression in normal tissues according to GTEx for RN7SK Gene

This gene is overexpressed in Kidney - Cortex (x5.1).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for RN7SK

genes like me logo Genes that share expression patterns with RN7SK: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RN7SK Gene

Orthologs for RN7SK Gene

Evolution for RN7SK Gene

ENSEMBL:
Gene Tree for RN7SK (if available)
TreeFam:
Gene Tree for RN7SK (if available)

No data available for Orthologs for RN7SK Gene

Paralogs for RN7SK Gene

No data available for Paralogs for RN7SK Gene

Variants for RN7SK Gene

Additional dbSNP identifiers (rs#s) for RN7SK Gene

Structural Variations from Database of Genomic Variants (DGV) for RN7SK Gene

Variant ID Type Subtype PubMed ID
esv2759430 CNV loss 17122850

Additional Variant Information for RN7SK Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
RN7SK

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for RN7SK Gene

Disorders for RN7SK Gene

MalaCards: The human disease database

(3) MalaCards diseases for RN7SK Gene - From: LncRNADisease and DISEASES

- elite association - COSMIC cancer census association via MalaCards
Search RN7SK in MalaCards View complete list of genes associated with diseases

Additional Disease Information for RN7SK

genes like me logo Genes that share disorders with RN7SK: view

No data available for UniProtKB/Swiss-Prot and Genatlas for RN7SK Gene

Publications for RN7SK Gene

  1. Structural basis for recognition of human 7SK long noncoding RNA by the La-related protein Larp7. (PMID: 29946027) Eichhorn CD … Feigon J (Proceedings of the National Academy of Sciences of the United States of America 2018) 2 3
  2. 7SK RNA, a non-coding RNA regulating P-TEFb, a general transcription factor. (PMID: 19246988) Diribarne G … Bensaude O (RNA biology 2009) 2 3
  3. Regulation of two key nuclear enzymatic activities by the 7SK small nuclear RNA. (PMID: 17381310) He WJ … Zhou Q (Cold Spring Harbor symposia on quantitative biology 2006) 3 23
  4. Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4. (PMID: 16109377) Yang Z … Zhou Q (Molecular cell 2005) 3 23
  5. Phosphorylated positive transcription elongation factor b (P-TEFb) is tagged for inhibition through association with 7SK snRNA. (PMID: 14627702) Chen R … Zhou Q (The Journal of biological chemistry 2004) 3 23

Products for RN7SK Gene

Sources for RN7SK Gene