Free for academic non-profit institutions. Other users need a Commercial license

Aliases for RN7SK Gene

Subcategory (RNA class) for RN7SK Gene


Quality Score for this RNA gene is


Aliases for RN7SK Gene

  • RNA, 7SK Small Nuclear 2 3 5
  • RNA, 7SK, Nuclear 2 3
  • 7SK Small Nuclear RNA 3
  • 7SK 3

External Ids for RN7SK Gene

ORGUL Members for RN7SK Gene

Previous GeneCards Identifiers for RN7SK Gene

  • GC06U990106
  • GC06P052907
  • GC06P052968
  • GC06P052860
  • GC06P052691

Summaries for RN7SK Gene

GeneCards Summary for RN7SK Gene

RN7SK (RNA, 7SK Small Nuclear) is an RNA Gene, and is affiliated with the 7SK RNA class. Diseases associated with RN7SK include Acquired Immunodeficiency Syndrome and Gastric Cancer.

Gene Wiki entry for RN7SK Gene

Additional gene information for RN7SK Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RN7SK Gene

Genomics for RN7SK Gene

GeneHancer (GH) Regulatory Elements for RN7SK Gene

Promoters and enhancers for RN7SK Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH06J052992 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 650.7 -0.6 -579 4.1 ZFP64 DMAP1 YBX1 YY1 SLC30A9 ZNF213 E2F8 ZNF143 SP3 NFYC RN7SK GSTA4 GC06P052997 ENSG00000202198 MCM3 EFHC1 ICK TRAM2 GSTA3 GC06P052982
GH06J053009 Enhancer 0.9 ENCODE dbSUPER 0.4 +17.6 17564 7.1 HDAC1 PKNOX1 NFIB NEUROD1 SIN3A FOSL1 CTBP1 GATA3 ATF7 RCOR1 ICK FBXO9 GC06P053016 RN7SK ENSG00000202198
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around RN7SK on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the RN7SK gene promoter:
  • HEN1
  • oct-B3
  • Oct-B1
  • oct-B2
  • POU2F1
  • POU2F1a
  • POU2F2
  • POU2F2 (Oct-2.1)
  • POU2F2B
  • POU2F2C

Genomic Locations for RN7SK Gene

Genomic Locations for RN7SK Gene
332 bases
Plus strand
332 bases
Plus strand

Genomic View for RN7SK Gene

Genes around RN7SK on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RN7SK Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RN7SK Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RN7SK Gene

Proteins for RN7SK Gene

Post-translational modifications for RN7SK Gene

No Post-translational modifications

No data available for DME Specific Peptides for RN7SK Gene

Domains & Families for RN7SK Gene

Gene Families for RN7SK Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RN7SK: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RN7SK Gene

Function for RN7SK Gene

Molecular function for RN7SK Gene

GENATLAS Biochemistry:
small nuclear RNA,7SK

Animal Model Products

miRNA for RN7SK Gene

miRTarBase miRNAs that target RN7SK

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for RN7SK Gene

Localization for RN7SK Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for RN7SK gene
Compartment Confidence
nucleus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for RN7SK Gene

Pathways & Interactions for RN7SK Gene

SuperPathways for RN7SK Gene

No Data Available

Interacting Proteins for RN7SK Gene

Gene Ontology (GO) - Biological Process for RN7SK Gene


No data available for Pathways by source and SIGNOR curated interactions for RN7SK Gene

Drugs & Compounds for RN7SK Gene

No Compound Related Data Available

Transcripts for RN7SK Gene

mRNA/cDNA for RN7SK Gene

Alternative Splicing Database (ASD) splice patterns (SP) for RN7SK Gene

No ASD Table

Relevant External Links for RN7SK Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RN7SK Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for RN7SK Gene

mRNA differential expression in normal tissues according to GTEx for RN7SK Gene

This gene is overexpressed in Kidney - Cortex (x5.1).

NURSA nuclear receptor signaling pathways regulating expression of RN7SK Gene:

genes like me logo Genes that share expression patterns with RN7SK: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RN7SK Gene

Orthologs for RN7SK Gene

Evolution for RN7SK Gene

Gene Tree for RN7SK (if available)
Gene Tree for RN7SK (if available)

No data available for Orthologs for RN7SK Gene

Paralogs for RN7SK Gene

No data available for Paralogs for RN7SK Gene

Variants for RN7SK Gene

Sequence variations from dbSNP and Humsavar for RN7SK Gene

SNP ID Clin Chr 06 pos Variation AA Info Type
rs1000210850 -- 52,994,666(+) A/C upstream_transcript_variant
rs1000360756 -- 52,995,937(+) G/A non_coding_transcript_variant
rs1000885244 -- 52,996,159(+) T/G downstream_transcript_variant
rs1001172400 -- 52,993,837(+) C/T upstream_transcript_variant
rs1002126456 -- 52,994,698(+) T/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for RN7SK Gene

Variant ID Type Subtype PubMed ID
esv2759430 CNV loss 17122850

Additional Variant Information for RN7SK Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for RN7SK Gene

Disorders for RN7SK Gene

MalaCards: The human disease database

(2) MalaCards diseases for RN7SK Gene - From: LncRNADisease and DISEASES

Disorder Aliases PubMed IDs
acquired immunodeficiency syndrome
  • aids
gastric cancer
  • gastric cancer, somatic
- elite association - COSMIC cancer census association via MalaCards
Search RN7SK in MalaCards View complete list of genes associated with diseases

Additional Disease Information for RN7SK

genes like me logo Genes that share disorders with RN7SK: view

No data available for UniProtKB/Swiss-Prot and Genatlas for RN7SK Gene

Publications for RN7SK Gene

  1. 7SK RNA, a non-coding RNA regulating P-TEFb, a general transcription factor. (PMID: 19246988) Diribarne G … Bensaude O (RNA biology 2009) 2 3 58
  2. Regulation of two key nuclear enzymatic activities by the 7SK small nuclear RNA. (PMID: 17381310) He WJ … Zhou Q (Cold Spring Harbor symposia on quantitative biology 2006) 3 22 58
  3. Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4. (PMID: 16109377) Yang Z … Zhou Q (Molecular cell 2005) 3 22 58
  4. Phosphorylated positive transcription elongation factor b (P-TEFb) is tagged for inhibition through association with 7SK snRNA. (PMID: 14627702) Chen R … Zhou Q (The Journal of biological chemistry 2004) 3 22 58
  5. A human immunodeficiency virus type 1 Tat-like arginine-rich RNA-binding domain is essential for HEXIM1 to inhibit RNA polymerase II transcription through 7SK snRNA-mediated inactivation of P-TEFb. (PMID: 15169877) Yik JH … Zhou Q (Molecular and cellular biology 2004) 3 22 58

Products for RN7SK Gene

Sources for RN7SK Gene

Loading form....