Free for academic non-profit institutions. Other users need a Commercial license
RMI2 is a component of the BLM (RECQL3; MIM 604610) complex, which plays a role in homologous recombination-dependent DNA repair and is essential for genome stability (Xu et al., 2008 [PubMed 18923082]).[supplied by OMIM, Nov 2008] See more...
Aliases for RMI2 Gene
Aliases for RMI2 Gene
External Ids for RMI2 Gene
- HGNC: 28349
- Entrez Gene: 116028
- Ensembl: ENSG00000175643
- OMIM: 612426
- UniProtKB: Q96E14
Previous HGNC Symbols for RMI2 Gene
- C16orf75
Previous GeneCards Identifiers for RMI2 Gene
- GC16P011411
- GC16P011343
Summaries for RMI2 Gene
-
RMI2 is a component of the BLM (RECQL3; MIM 604610) complex, which plays a role in homologous recombination-dependent DNA repair and is essential for genome stability (Xu et al., 2008 [PubMed 18923082]).[supplied by OMIM, Nov 2008]
GeneCards Summary for RMI2 Gene
RMI2 (RecQ Mediated Genome Instability 2) is a Protein Coding gene. Diseases associated with RMI2 include Microcephaly, Growth Restriction, And Increased Sister Chromatid Exchange 2 and Malignant Ovarian Cyst. Among its related pathways are Homologous DNA Pairing and Strand Exchange and Regulation of TP53 Activity.
UniProtKB/Swiss-Prot Summary for RMI2 Gene
-
Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates. It is required to regulate sister chromatid segregation and to limit DNA crossover. Essential for the stability, localization, and function of BLM, TOP3A, and complexes containing BLM. In the RMI complex, it is required to target BLM to chromatin and stress-induced nuclear foci and mitotic phosphorylation of BLM.
Additional gene information for RMI2 Gene
- HGNC(28349)
- Entrez Gene(116028)
- Ensembl(ENSG00000175643)
- OMIM(612426)
- UniProtKB(Q96E14)
- Open Targets Platform(ENSG00000175643)
- Search for RMI2 at DataMed
- Search for RMI2 at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for RMI2 Gene
Genomics for RMI2 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for RMI2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around RMI2 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for RMI2
Genomic Locations for RMI2 Gene
Genomic Locations for RMI2 Gene
- chr16:11,249,619-11,381,662
- (GRCh38/hg38)
- Size:
- 132,044 bases
- Orientation:
- Plus strand
- chr16:11,343,476-11,445,619
- (GRCh37/hg19)
- Size:
- 102,144 bases
- Orientation:
- Plus strand
Genomic View for RMI2 Gene
Genes around RMI2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 16p13.13 by HGNC
- 16p13.13 by Entrez Gene
- 16p13.13 by Ensembl
RMI2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for RMI2 Gene
Proteins for RMI2 Gene
-
Protein details for RMI2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q96E14-RMI2_HUMAN
- Recommended name:
- RecQ-mediated genome instability protein 2
- Protein Accession:
- Q96E14
- B3KVZ6
- Q49AE2
- Q8TBL0
Protein attributes for RMI2 Gene
- Size:
- 147 amino acids
- Molecular mass:
- 15865 Da
- Quaternary structure:
-
- Component of the RMI complex, containing at least TOP3A, RMI1 and RMI2. The RMI complex interacts with BLM.
Protein Expression for RMI2 Gene
Post-translational modifications for RMI2 Gene
- Phosphorylated during mitosis.
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for RMI2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- NSJ Bioreagents RMI2 Antibody / RecQ-mediated genome instability protein 2
- Novus Biologicals Antibodies for RMI2
- Invitrogen Antibodies for RMI2 (AFLGC-RMI2)
-
Boster Bio Antibodies for RMI2
Protein Products
-
OriGene Purified Proteins for RMI2
- Search Origene for MassSpec and Protein Over-expression Lysates for RMI2
- Origene Custom Protein Services for RMI2
- Novus Biologicals proteins for RMI2
Assay Products
- antibodies-online: Show 6 available RMI2 Elisa Kits ranked by validation data
- Compare Top RMI2 Elisa Kits
-
Quality Products:
-
Signalway ELISA kits for RMI2
No data available for DME Specific Peptides for RMI2 Gene
Domains & Families for RMI2 Gene
Gene Families for RMI2 Gene
- Human Protein Atlas (HPA):
-
- Cancer-related genes
- Disease related genes
- Predicted intracellular proteins
Suggested Antigen Peptide Sequences for RMI2 Gene
- GenScript: Design optimal peptide antigens:
-
- BLM-associated protein of 18 kDa (RMI2_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q96E14- Family:
-
- Belongs to the RMI2 family.
Function for RMI2 Gene
Molecular function for RMI2 Gene
- UniProtKB/Swiss-Prot Function:
- Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates. It is required to regulate sister chromatid segregation and to limit DNA crossover. Essential for the stability, localization, and function of BLM, TOP3A, and complexes containing BLM. In the RMI complex, it is required to target BLM to chromatin and stress-induced nuclear foci and mitotic phosphorylation of BLM.
Phenotypes From GWAS Catalog for RMI2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | -- |
| GO:0005515 | protein binding | IPI | 20711169 |
Phenotypes for RMI2 Gene
- GenomeRNAi human phenotypes for RMI2:
-
- Increased vaccinia virus (VACV) infection
- no effect
- Synthetic lethal with MLN4924 (a NAE inhibitor)
- Increased viability with MLN4924 (a NAE inhibitor)
- Decreased epidermal growth factor (EGF) endocytosis, decreased transferrin (TF) endocytosis
- Synthetic lethal with Ras
- Increased ionizing radiation sensitivity
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for RMI2 - Select products 50% OFF >
- * RMI2 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for RMI2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RMI2
-
Santa Cruz Biotechnology (SCBT) CRISPR for RMI2
miRNA for RMI2 Gene
- miRTarBase miRNAs that target RMI2
-
- hsa-miR-4480 (MIRT562768)
- hsa-miR-573 (MIRT562769)
- hsa-miR-3616-5p (MIRT562770)
- hsa-miR-3190-3p (MIRT562771)
- hsa-miR-4795-5p (MIRT562772)
- hsa-miR-548at-5p (MIRT562773)
- mmu-miR-151-3p (MIRT579496)
- mmu-miR-342-3p (MIRT579497)
- mmu-miR-377-3p (MIRT579498)
- mmu-miR-5101 (MIRT588168)
- mmu-miR-1896 (MIRT588169)
- mmu-miR-129-1-3p (MIRT588170)
- mmu-miR-129-2-3p (MIRT588171)
- mmu-miR-3085-3p (MIRT588172)
- mmu-miR-3064-5p (MIRT588173)
- mmu-miR-3097-3p (MIRT599923)
- mmu-miR-717 (MIRT599924)
- mmu-miR-329-3p (MIRT599925)
- mmu-miR-362-3p (MIRT599926)
- mmu-miR-544-5p (MIRT599927)
- mmu-miR-3084-3p (MIRT599928)
- mmu-miR-5125 (MIRT599929)
- mmu-miR-3110-5p (MIRT599930)
- mmu-miR-3109-3p (MIRT599931)
- mmu-miR-3102-5p (MIRT599932)
- mmu-miR-546 (MIRT599933)
- mmu-miR-1935 (MIRT599934)
- mmu-miR-298-5p (MIRT599935)
- mmu-miR-876-5p (MIRT599936)
- mmu-miR-3089-5p (MIRT599937)
- mmu-miR-1195 (MIRT599938)
- mmu-miR-5135 (MIRT599939)
- mmu-miR-10b-5p (MIRT599940)
- mmu-miR-10a-5p (MIRT599941)
- mmu-miR-339-5p (MIRT599942)
- mmu-miR-3065-5p (MIRT599943)
- mmu-miR-3473d (MIRT602857)
- mmu-miR-674-5p (MIRT602859)
- mmu-miR-3961 (MIRT602860)
- mmu-miR-709 (MIRT602861)
- mmu-miR-1199-5p (MIRT602862)
- mmu-miR-665-3p (MIRT602863)
- mmu-miR-3082-5p (MIRT604436)
- mmu-miR-706 (MIRT604437)
- mmu-miR-5113 (MIRT605886)
- mmu-miR-466f-3p (MIRT791432)
- mmu-miR-466q (MIRT791575)
- mmu-miR-467f (MIRT791714)
- mmu-miR-5617-5p (MIRT791782)
- mmu-miR-6380 (MIRT791791)
- mmu-miR-669c-3p (MIRT791883)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for RMI2
- Browse OriGene Inhibitory RNA Products For RMI2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RMI2
Clone Products
- Applied Biological Materials (abm): Clones for RMI2 - Select products 50% OFF >
- * RMI2 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for RMI2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RMI2
Cell Line Products
-
Horizon Cell Lines for RMI2
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for RMI2 Gene
Localization for RMI2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for RMI2 Gene
- Nucleus. Note=Colocalizes with BLM at nuclear DNA repair foci.
| Compartment | Confidence |
|---|---|
| cytosol | 5 |
| nucleus | 4 |
| plasma membrane | 1 |
| extracellular | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
- Cytosol (3)
- Nuclear speckles (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005829 | cytosol | IBA,IDA | -- |
| GO:0016607 | nuclear speck | IBA,IDA | -- |
Pathways & Interactions for RMI2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | DNA Double-Strand Break Repair |
.53
|
|
| 2 | Homologous DNA Pairing and Strand Exchange | ||
| 3 | Regulation of TP53 Activity | ||
| 4 | Resolution of D-loop Structures through Holliday Junction Intermediates | ||
| 5 | Cell Cycle Checkpoints |
.84
|
|
Pathways by source for RMI2 Gene
21 Reactome pathways for RMI2 Gene
1 KEGG pathway for RMI2 Gene
Interacting Proteins for RMI2 Gene
Selected Interacting proteins:
Q96E14-RMI2_HUMAN
ENSP00000310356
for RMI2 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for RMI2
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006260 | DNA replication | TAS | -- |
| GO:0006281 | DNA repair | IBA | 21873635 |
| GO:0033045 | regulation of sister chromatid segregation | IMP | 27977684 |
| GO:0043007 | maintenance of rDNA | IBA | 21873635 |
| GO:1901796 | regulation of signal transduction by p53 class mediator | TAS | -- |
No data available for SIGNOR curated interactions for RMI2 Gene
Transcripts for RMI2 Gene
mRNA/cDNA for RMI2 Gene
- 1 REFSEQ mRNAs :
- 6 NCBI additional mRNA sequence :
- 7 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000312499 1427 nts (view in UCSC)
- ENST00000572173 1865 nts (view in UCSC)
- ENST00000572992 934 nts (view in UCSC)
- ENST00000573910 670 nts (view in UCSC)
- ENST00000576027 818 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for RMI2 - Select products 50% OFF >
- * RMI2 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for RMI2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RMI2
-
Santa Cruz Biotechnology (SCBT) CRISPR for RMI2
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for RMI2
- Browse OriGene Inhibitory RNA Products For RMI2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RMI2
Clone Products
- Applied Biological Materials (abm): Clones for RMI2 - Select products 50% OFF >
- * RMI2 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for RMI2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RMI2
Relevant External Links for RMI2 Gene
- GeneLoc Exon Structure for
- RMI2
Expression for RMI2 Gene
mRNA differential expression in normal tissues according to GTEx for RMI2 Gene
This gene is overexpressed in Testis (x4.7).
This gene is overexpressed in Fetal ovary (61.3) and Fetal heart (6.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for RMI2 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for RMI2
SOURCE GeneReport for Unigene cluster for RMI2 Gene:
Hs.347524Evidence on tissue expression from TISSUES for RMI2 Gene
- Skin(4.4)
- Lung(4.1)
Primer Products
-
OriGene qPCR primer pairs for RMI2
-
OriGene qPCR primer pairs and template standards for RMI2
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for RMI2 Gene
Orthologs for RMI2 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | RMI2 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | RMI2 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | RMI2 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Rmi2 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Rmi2 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | RMI2 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | RMI2 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | RMI2 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | rmi2 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | LOC563218 30 |
|
||
| RMI2 31 |
|
OneToOne |
- Species where no ortholog for RMI2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for RMI2 Gene
- ENSEMBL:
- Gene Tree for RMI2 (if available)
- TreeFam:
- Gene Tree for RMI2 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for RMI2: view image
Paralogs for RMI2 Gene
No data available for Paralogs for RMI2 Gene
Variants for RMI2 Gene
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv2728n100 | CNV | gain | 25217958 |
| nsv1040428 | CNV | gain | 25217958 |
Gene Damage Index Score:
0.44;
9.64% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for RMI2 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for RMI2 Gene
Disorders for RMI2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| microcephaly, growth restriction, and increased sister chromatid exchange 2 |
|
|
| malignant ovarian cyst |
|
|
| bloom syndrome |
|
|
| baller-gerold syndrome |
|
|
| rapadilino syndrome |
|
|
Search RMI2 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
RMI2_HUMAN- Note=A homozygous deletion of RMI2 has been found in a family with a Bloom-like syndrome and is probable responsible for the phenotype. Patients manifest depigmented skin lesions, multiple cafe-au-lait macules, and growth deficiency. Cells from affected individuals show a high rate of sister chromatid exchange and increased chromosomal breaks. {ECO:0000269 PubMed:27977684}.
Additional Disease Information for RMI2
No data available for Genatlas for RMI2 Gene
Publications for RMI2 Gene
- BLAP18/RMI2, a novel OB-fold-containing protein, is an essential component of the Bloom helicase-double Holliday junction dissolvasome. (PMID: 18923083) Singh TR … Meetei AR (Genes & development 2008) 2 3 4
- Loss of RMI2 Increases Genome Instability and Causes a Bloom-Like Syndrome. (PMID: 27977684) Hudson DF … Kalitsis P (PLoS genetics 2016) 3 4
- Structure and cellular roles of the RMI core complex from the bloom syndrome dissolvasome. (PMID: 20826341) Hoadley KA … Keck JL (Structure (London, England : 1993) 2010) 2 3
- RMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stability. (PMID: 18923082) Xu D … Wang W (Genes & development 2008) 3 4
- H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids. (PMID: 30804502) Nakamura K … Groth A (Nature cell biology 2019) 3
ExternalLinks
Products for RMI2 Gene
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for RMI2
- Search Origene for MassSpec and Protein Over-expression Lysates for RMI2
- Origene Custom Protein Services for RMI2
- Origene shrna, sirna, and RNAi products in human, mouse, rat for RMI2
- Browse OriGene Inhibitory RNA Products For RMI2
- OriGene qPCR primer pairs for RMI2
- OriGene qPCR primer pairs and template standards for RMI2
- OriGene CRISPR knockouts for RMI2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For RMI2
- Sino Biological Human cDNA Clone for RMI2
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for RMI2
- Novus Biologicals proteins for RMI2
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Invitrogen Antibodies for RMI2 (AFLGC-RMI2)
- VectorBuilder Custom and pre-made DNA vectors for RMI2 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for RMI2 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for RMI2 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for RMI2 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for RMI2
- antibodies-online: Show 9 available RMI2 Antibodies ranked by validation data
- Compare Top RMI2 Antibodies
- antibodies-online: Show 6 available RMI2 Elisa Kits ranked by validation data
- Compare Top RMI2 Elisa Kits
- Quality Products:
- antibodies-online: Show 4 available RMI2 Proteins ranked by validation data
- Compare Top RMI2 Proteins
- Horizon Cell Lines for RMI2
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RMI2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RMI2
- Search GeneCopoeia for miRNA 3'UTR Target clone products for RMI2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RMI2
- Boster Bio Antibodies for RMI2
- Browse Boster Bio ELISA Kits
- Signalway ELISA kits for RMI2
Sources for RMI2 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB