Aliases for RLN3 Gene
External Ids for RLN3 Gene
Previous GeneCards Identifiers for RLN3 Gene
This gene encodes a member of the relaxin family of insulin-like hormones that is expressed predominantly in the brain and plays a role in physiological processes such as stress, memory and appetite regulation. The encoded protein is a precursor that is proteolytically processed to generate a heterodimeric mature form consisting A and B chains interlinked by disulfide bonds. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2015]
GeneCards Summary for RLN3 Gene
RLN3 (Relaxin 3) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors. Gene Ontology (GO) annotations related to this gene include hormone activity and G protein-coupled receptor binding. An important paralog of this gene is INSL5.
UniProtKB/Swiss-Prot Summary for RLN3 Gene
May play a role in neuropeptide signaling processes. Ligand for LGR7, RXFP3 and RXFP4.