Aliases for RIT2 Gene
External Ids for RIT2 Gene
Previous HGNC Symbols for RIT2 Gene
Previous GeneCards Identifiers for RIT2 Gene
RIN belongs to the RAS (HRAS; MIM 190020) superfamily of small GTPases (Shao et al., 1999 [PubMed 10545207]).[supplied by OMIM, Mar 2008]
GeneCards Summary for RIT2 Gene
RIT2 (Ras Like Without CAAX 2) is a Protein Coding gene. Diseases associated with RIT2 include Amyotrophic Lateral Sclerosis, Juvenile, With Dementia and Angular Cheilitis. Among its related pathways are RET signaling and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include GTP binding and calmodulin binding. An important paralog of this gene is RIT1.
UniProtKB/Swiss-Prot Summary for RIT2 Gene
Binds and exchanges GTP and GDP. Binds and modulates the activation of POU4F1 as gene expression regulator.