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RIPPLY3 (Ripply Transcriptional Repressor 3) is a Protein Coding gene. Diseases associated with RIPPLY3 include Down Syndrome and Cardiomyopathy, Dilated, 1J. An important paralog of this gene is RIPPLY1.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005515 | protein binding | IPI | 30241482 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | IBA,NAS | 10814524 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000122 | negative regulation of transcription by RNA polymerase II | IEA,IBA | 21873635 |
GO:0007275 | multicellular organism development | IEA | -- |
GO:0007507 | heart development | IEA | -- |
GO:0008150 | biological_process | ND | -- |
GO:0008285 | negative regulation of cell proliferation | IEA | -- |
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | DSCR6 30 |
|
||
RIPPLY3 31 |
|
OneToOne | |||
Dog (Canis familiaris) |
Mammalia | DSCR6 30 |
|
||
RIPPLY3 31 |
|
OneToOne | |||
Cow (Bos Taurus) |
Mammalia | RIPPLY3 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Ripply3 30 17 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Ripply3 30 |
|
||
Platypus (Ornithorhynchus anatinus) |
Mammalia | RIPPLY3 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | DSCR6 30 |
|
||
RIPPLY3 31 |
|
OneToOne | |||
Zebrafish (Danio rerio) |
Actinopterygii | ripply3 31 |
|
OneToOne |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv2751929 | CNV | gain | 17911159 |
esv2763684 | CNV | gain+loss | 21179565 |
esv3568184 | CNV | loss | 25503493 |
Disorder | Aliases | PubMed IDs |
---|---|---|
down syndrome |
|
|
cardiomyopathy, dilated, 1j |
|
|
branchiootorenal syndrome 1 |
|
|
amyotrophic lateral sclerosis 1 |
|
|