Aliases for RIPOR1 Gene
External Ids for RIPOR1 Gene
Previous HGNC Symbols for RIPOR1 Gene
GeneCards Summary for RIPOR1 Gene
RIPOR1 (RHO Family Interacting Cell Polarization Regulator 1) is a Protein Coding gene. Diseases associated with RIPOR1 include Cerebral Cavernous Malformations 3 and Central Nervous System Hemangioma. An important paralog of this gene is RIPOR2.
UniProtKB/Swiss-Prot for RIPOR1 Gene
Downstream effector protein for Rho-type small GTPases that plays a role in cell polarity and directional migration (PubMed:27807006). Acts as an adapter protein, linking active Rho proteins to STK24 and STK26 kinases, and hence positively regulates Golgi reorientation in polarized cell migration upon Rho activation (PubMed:27807006). Involved in the subcellular relocation of STK26 from the Golgi to cytoplasm punctae in a Rho- and PDCD10-dependent manner upon serum stimulation (PubMed:27807006).