Aliases for RIPK4 Gene
External Ids for RIPK4 Gene
Previous HGNC Symbols for RIPK4 Gene
Previous GeneCards Identifiers for RIPK4 Gene
The protein encoded by this gene is a serine/threonine protein kinase that interacts with protein kinase C-delta. The encoded protein can also activate NFkappaB and is required for keratinocyte differentiation. This kinase undergoes autophosphorylation. [provided by RefSeq, Jul 2008]
GeneCards Summary for RIPK4 Gene
RIPK4 (Receptor Interacting Serine/Threonine Kinase 4) is a Protein Coding gene. Diseases associated with RIPK4 include Bartsocas-Papas Syndrome and Chand Syndrome. Among its related pathways are NF-kappaB Signaling and Wnt / Hedgehog / Notch. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is ANKK1.
UniProtKB/Swiss-Prot Summary for RIPK4 Gene
Involved in stratified epithelial development. It is a direct transcriptional target of TP63. Plays a role in NF-kappa-B activation.