The protein encoded by this gene is a serine/threonine protein kinase that interacts with protein kinase C-delta. The encoded protein can also activate NFkappaB and is required for keratinocyte differentiation. This kinase undergoes autophosphorylation. [provided by RefSeq, Jul 2008] See more...

Aliases for RIPK4 Gene

Aliases for RIPK4 Gene

  • Receptor Interacting Serine/Threonine Kinase 4 2 3 5
  • PKC-Delta-Interacting Protein Kinase 2 3 4
  • DIK 2 3 4
  • Receptor-Interacting Serine/Threonine-Protein Kinase 4 3 4
  • Ankyrin Repeat Domain-Containing Protein 3 3 4
  • Protein Kinase C-Associated Kinase 2 3
  • EC 4 51
  • ANKRD3 3 4
  • ANKK2 2 3
  • RIP4 2 3
  • PKK 2 3
  • Receptor-Interacting Serine-Threonine Kinase 4 2
  • Serine/Threonine-Protein Kinase ANKRD3 3
  • Ankyrin Repeat Domain 3 2
  • EC 2.7.11 51
  • CHANDS 3
  • NKRD3 3
  • RIPK4 5
  • PPS2 3

External Ids for RIPK4 Gene

Previous HGNC Symbols for RIPK4 Gene

  • ANKRD3

Previous GeneCards Identifiers for RIPK4 Gene

  • GC00U917001
  • GC21M042032
  • GC21M043159
  • GC21M028579

Summaries for RIPK4 Gene

Entrez Gene Summary for RIPK4 Gene

  • The protein encoded by this gene is a serine/threonine protein kinase that interacts with protein kinase C-delta. The encoded protein can also activate NFkappaB and is required for keratinocyte differentiation. This kinase undergoes autophosphorylation. [provided by RefSeq, Jul 2008]

GeneCards Summary for RIPK4 Gene

RIPK4 (Receptor Interacting Serine/Threonine Kinase 4) is a Protein Coding gene. Diseases associated with RIPK4 include Bartsocas-Papas Syndrome and Chand Syndrome. Among its related pathways are NF-kappaB Signaling and Wnt / Hedgehog / Notch. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is ANKK1.

UniProtKB/Swiss-Prot Summary for RIPK4 Gene

  • Involved in stratified epithelial development. It is a direct transcriptional target of TP63. Plays a role in NF-kappa-B activation.

Gene Wiki entry for RIPK4 Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for RIPK4 Gene

Genomics for RIPK4 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for RIPK4 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH21J041760 Promoter/Enhancer 2.1 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 607.2 +1.1 1146 10.8 CREB1 GATAD2A CTCF PRDM10 ZNF629 REST TFE3 SOX13 NFKBIZ ZNF692 RIPK4 LOC102724800 LINC00479 PRDM15 ENSG00000236883 LINC00112 MX2 ZBTB21 MX1 ABCG1
GH21J041112 Enhancer 1.1 FANTOM5 ENCODE CraniofacialAtlas 5.2 +653.6 653613 1.6 CREB1 ZNF512 RFX5 TARDBP GTF2F1 CTBP1 GABPA PKNOX1 ZNF217 CUX1 BACE2 RIPK4 piR-60051-066 ENSG00000286425 DSCAM
GH21J041668 Enhancer 0.4 FANTOM5 dbSUPER 4.1 +98.1 98103 0.3 LOC107985478 LOC105372813 RIPK4 LINC00111 TMPRSS2
GH21J041756 Enhancer 1.4 Ensembl ENCODE CraniofacialAtlas dbSUPER 0.4 +13.9 13912 6.8 GATAD2A ZNF629 TFE3 NFKBIZ RCOR2 ZIC2 PKNOX1 RXRB PATZ1 SP1 LINC00479 LINC00112 PRDM15 MIR6814 RIPK4 TMPRSS2
GH21J041782 Enhancer 1.3 Ensembl ENCODE dbSUPER 0.4 -18.0 -18012 5.4 RNF2 CREB1 PRDM10 ZNF629 ZNF692 TARDBP FOXA1 ZIC2 ZSCAN4 PKNOX1 PRDM15 ENSG00000233754 ENSG00000227698 LINC00112 LINC00479 TFF3 lnc-PRDM15-1 RIPK4 lnc-UMODL1-4
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around RIPK4 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for RIPK4

Top Transcription factor binding sites by QIAGEN in the RIPK4 gene promoter:
  • AML1a
  • AP-2gamma
  • c-Myc
  • CP2
  • CREB
  • deltaCREB
  • Lmo2
  • Max1
  • Nkx2-5
  • RP58

Genomic Locations for RIPK4 Gene

Genomic Locations for RIPK4 Gene
27,721 bases
Minus strand
27,738 bases
Minus strand

Genomic View for RIPK4 Gene

Genes around RIPK4 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RIPK4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RIPK4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RIPK4 Gene

Proteins for RIPK4 Gene

  • Protein details for RIPK4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Receptor-interacting serine/threonine-protein kinase 4
    Protein Accession:
    Secondary Accessions:
    • Q96KH0

    Protein attributes for RIPK4 Gene

    832 amino acids
    Molecular mass:
    91611 Da
    Quaternary structure:
    • Interacts with PRKCB (By similarity). Interacts with TRAF1, TRAF2, TRAF3 and TRAF5. Interacts with BIRC2/c-IAP1, BIRC3/c-IAP2 and XIAP/BIRC4.

    Alternative splice isoforms for RIPK4 Gene


neXtProt entry for RIPK4 Gene

Selected DME Specific Peptides for RIPK4 Gene


Post-translational modifications for RIPK4 Gene

  • May be phosphorylated by MAP3K2 and MAP3K3.
  • Proteolytically cleaved by during Fas-induced apoptosis. Cleavage at Asp-388 and Asp-426.
  • Polyubiquitinated with 'Lys-48' and 'Lys-63'-linked chains by BIRC2/c-IAP1 and BIRC3/c-IAP2, leading to activation of NF-kappa-B.
  • Ubiquitination at Lys51 and Lys145
  • Modification sites at PhosphoSitePlus

Other Protein References for RIPK4 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

  • Abcam antibodies for RIPK4
  • Boster Bio Antibodies for RIPK4

Domains & Families for RIPK4 Gene

Gene Families for RIPK4 Gene

Human Protein Atlas (HPA):
  • Disease related genes
  • Enzymes
  • Potential drug targets
  • Predicted intracellular proteins

Protein Domains for RIPK4 Gene

Suggested Antigen Peptide Sequences for RIPK4 Gene

GenScript: Design optimal peptide antigens:
  • cDNA, FLJ79311, highly similar to Receptor-interacting serine/threonine-protein kinase 4 (EC (B7ZAU7_HUMAN)
  • Receptor-interacting serine-threonine kinase 4, isoform CRA_b (Q2TB16_HUMAN)
  • Protein kinase (Q9H4D1_HUMAN)
  • PKC-delta-interacting protein kinase (RIPK4_HUMAN)

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
  • Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
genes like me logo Genes that share domains with RIPK4: view

Function for RIPK4 Gene

Molecular function for RIPK4 Gene

UniProtKB/Swiss-Prot Function:
Involved in stratified epithelial development. It is a direct transcriptional target of TP63. Plays a role in NF-kappa-B activation.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616, ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=;.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060, Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013, ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216; EC=;.

Enzyme Numbers (IUBMB) for RIPK4 Gene

Phenotypes From GWAS Catalog for RIPK4 Gene

Gene Ontology (GO) - Molecular Function for RIPK4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000166 nucleotide binding IEA --
GO:0004672 protein kinase activity IEA --
GO:0004674 protein serine/threonine kinase activity IEA --
GO:0005515 protein binding IPI 21931591
GO:0005524 ATP binding IEA --
genes like me logo Genes that share ontologies with RIPK4: view
genes like me logo Genes that share phenotypes with RIPK4: view

Human Phenotype Ontology for RIPK4 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for RIPK4 Gene

MGI Knock Outs for RIPK4:
  • Ripk4 Ripk4<tm1Pmh>
  • Ripk4 Ripk4<tm1a(EUCOMM)Wtsi>

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RIPK4

No data available for Transcription Factor Targets and HOMER Transcription for RIPK4 Gene

Localization for RIPK4 Gene

Subcellular locations from UniProtKB/Swiss-Prot for RIPK4 Gene

Cytoplasm. Membrane. Peripheral membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for RIPK4 gene
Compartment Confidence
cytosol 4
nucleus 3
plasma membrane 1
extracellular 1
cytoskeleton 1
mitochondrion 1
endoplasmic reticulum 1
endosome 1
lysosome 1
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for RIPK4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm ISS --
GO:0016020 membrane IEA --
genes like me logo Genes that share ontologies with RIPK4: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for RIPK4 Gene

Pathways & Interactions for RIPK4 Gene

PathCards logo

SuperPathways for RIPK4 Gene

genes like me logo Genes that share pathways with RIPK4: view

Pathways by source for RIPK4 Gene

2 Cell Signaling Technology pathways for RIPK4 Gene

Gene Ontology (GO) - Biological Process for RIPK4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002009 morphogenesis of an epithelium IMP 22197488
GO:0006468 protein phosphorylation IEA --
GO:0016310 phosphorylation IEA --
GO:0051092 positive regulation of NF-kappaB transcription factor activity IMP 21931591
genes like me logo Genes that share ontologies with RIPK4: view

No data available for SIGNOR curated interactions for RIPK4 Gene

Drugs & Compounds for RIPK4 Gene

(4) Drugs for RIPK4 Gene - From: DrugBank, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
fostamatinib Approved, Investigational Pharma Target, inhibitor Kinase Inhibitors 0
ATP Investigational Nutra Agonist, Activator, Partial agonist, Antagonist, Full agonist, Gating inhibitor, Pore Blocker, Potentiation 0

(2) Additional Compounds for RIPK4 Gene - From: HMDB and Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
  • 5'-Adenylphosphoric acid
  • Adenosine 5'-diphosphate
  • ADENOSINE-5'-diphosphATE
  • H3ADP
  • 5'-Adenylphosphate
Agonist, Full agonist, Partial agonist, Gating inhibitor, Antagonist 58-64-0
genes like me logo Genes that share compounds with RIPK4: view

Transcripts for RIPK4 Gene

mRNA/cDNA for RIPK4 Gene

12 NCBI additional mRNA sequence :
2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RIPK4

Alternative Splicing Database (ASD) splice patterns (SP) for RIPK4 Gene

No ASD Table

Relevant External Links for RIPK4 Gene

GeneLoc Exon Structure for

Expression for RIPK4 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for RIPK4 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for RIPK4 Gene

This gene is overexpressed in Esophagus - Mucosa (x12.0).

Protein differential expression in normal tissues from HIPED for RIPK4 Gene

This gene is overexpressed in Bone (36.5) and Urine (32.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for RIPK4 Gene

Protein tissue co-expression partners for RIPK4 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for RIPK4

SOURCE GeneReport for Unigene cluster for RIPK4 Gene:


mRNA Expression by UniProt/SwissProt for RIPK4 Gene:

Tissue specificity: Expressed in hair follicles and skin.

Evidence on tissue expression from TISSUES for RIPK4 Gene

  • Lung(4.3)
  • Skin(2.5)
  • Blood(2.3)
  • Nervous system(2.1)
  • Liver(2.1)
  • Kidney(2)

Phenotype-based relationships between genes and organs from Gene ORGANizer for RIPK4 Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
  • digestive
  • endocrine
  • integumentary
  • nervous
  • reproductive
  • skeletal muscle
  • skeleton
Head and neck:
  • brain
  • chin
  • ear
  • eye
  • eyelid
  • face
  • forehead
  • head
  • jaw
  • lip
  • mandible
  • maxilla
  • mouth
  • neck
  • nose
  • outer ear
  • skull
  • chest wall
  • clavicle
  • rib
  • rib cage
  • scapula
  • sternum
  • intestine
  • large intestine
  • anus
  • pelvis
  • penis
  • rectum
  • vagina
  • vulva
  • ankle
  • arm
  • digit
  • elbow
  • femur
  • fibula
  • finger
  • foot
  • forearm
  • hand
  • hip
  • humerus
  • knee
  • lower limb
  • nail
  • radius
  • shin
  • shoulder
  • thigh
  • tibia
  • toe
  • ulna
  • upper limb
  • wrist
  • hair
  • skin
  • spinal column
  • vertebrae
genes like me logo Genes that share expression patterns with RIPK4: view

Orthologs for RIPK4 Gene

This gene was present in the common ancestor of chordates.

Orthologs for RIPK4 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia RIPK4 30 31
  • 98.94 (n)
(Bos Taurus)
Mammalia RIPK4 30 31
  • 86.65 (n)
(Canis familiaris)
Mammalia RIPK4 30 31
  • 86.58 (n)
(Mus musculus)
Mammalia Ripk4 30 17 31
  • 84.91 (n)
(Rattus norvegicus)
Mammalia Ripk4 30
  • 84.86 (n)
(Monodelphis domestica)
Mammalia RIPK4 31
  • 83 (a)
(Ornithorhynchus anatinus)
Mammalia RIPK4 31
  • 81 (a)
(Gallus gallus)
Aves RIPK4 30 31
  • 72.61 (n)
(Anolis carolinensis)
Reptilia RIPK4 31
  • 75 (a)
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia ripk4 30
  • 69.4 (n)
African clawed frog
(Xenopus laevis)
Amphibia ankrd3-prov 30
(Danio rerio)
Actinopterygii ripk4 30 31
  • 64.4 (n)
Dr.18839 30
Sea Squirt
(Ciona savignyi)
Ascidiacea -- 31
  • 29 (a)
Species where no ortholog for RIPK4 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for RIPK4 Gene

Gene Tree for RIPK4 (if available)
Gene Tree for RIPK4 (if available)
Evolutionary constrained regions (ECRs) for RIPK4: view image

Paralogs for RIPK4 Gene

Paralogs for RIPK4 Gene

(14) SIMAP similar genes for RIPK4 Gene using alignment to 3 proteins:

  • Q2TB16_HUMAN
genes like me logo Genes that share paralogs with RIPK4: view

Variants for RIPK4 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for RIPK4 Gene

SNP ID Clinical significance and condition Chr 21 pos Variation AA Info Type
716721 Conflicting Interpretations: Bartsocas-Papas syndrome; not provided 41,746,611(-) A/G SPLICE_DONOR_VARIANT
718327 Benign: Bartsocas-Papas syndrome; not provided 41,743,958(-) C/A SYNONYMOUS_VARIANT
718916 Likely Benign: not provided 41,751,120(-) G/A SYNONYMOUS_VARIANT
726347 Likely Benign: not provided 41,756,669(-) C/T SYNONYMOUS_VARIANT
730923 Likely Benign: not provided 41,741,735(-) G/A SYNONYMOUS_VARIANT

Additional dbSNP identifiers (rs#s) for RIPK4 Gene

Structural Variations from Database of Genomic Variants (DGV) for RIPK4 Gene

Variant ID Type Subtype PubMed ID
esv3893416 CNV gain 25118596
esv3893417 CNV gain 25118596
nsv1065094 CNV loss 25217958
nsv459265 CNV loss 19166990
nsv587562 CNV loss 21841781

Variation tolerance for RIPK4 Gene

Residual Variation Intolerance Score: 12.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.80; 79.10% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for RIPK4 Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RIPK4 Gene

Disorders for RIPK4 Gene

MalaCards: The human disease database

(10) MalaCards diseases for RIPK4 Gene - From: UniProtKB/Swiss-Prot, OMIM, ClinVar, GTR, Orphanet, DISEASES, and GeneCards

- elite association - COSMIC cancer census association via MalaCards
Search RIPK4 in MalaCards View complete list of genes associated with diseases


  • Bartsocas-Papas syndrome (BPS) [MIM:263650]: An autosomal recessive disorder characterized by multiple popliteal pterygia leading to severe arthrogryposis, ankyloblepharon filiforme adnatum, filiform bands between the jaws, synostosis of the carpal/tarsal and phalangeal bones in the hands and feet, digital hypoplasia/aplasia, complete soft-tissue syndactyly, lack of nails, lack of scalp hair, eyebrows and eyelashes, blepharophimosis, cleft lip and/or palate, and hypoplastic external genitalia. Early lethality is common, although survival into childhood and beyond has been reported. {ECO:0000269 PubMed:22197488, ECO:0000269 PubMed:22197489}. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • CHAND syndrome (CHANDS) [MIM:214350]: An autosomal recessive syndrome characterized by ankyloblepharon, sparse, curly and woolly hair, nail dysplasia, and oral frenula. {ECO:0000269 PubMed:23610050, ECO:0000269 PubMed:26129644}. Note=The disease may be caused by mutations affecting the gene represented in this entry.

Additional Disease Information for RIPK4

Genetic Association Database
Human Genome Epidemiology Navigator
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
genes like me logo Genes that share disorders with RIPK4: view

No data available for Genatlas for RIPK4 Gene

Publications for RIPK4 Gene

  1. RIP4 (DIK/PKK), a novel member of the RIP kinase family, activates NF-kappa B and is processed during apoptosis. (PMID: 12446564) Meylan E … Tschopp J (EMBO reports 2002) 3 4 23
  2. The DNA sequence of human chromosome 21. (PMID: 10830953) Hattori M … Chromosome 21 mapping and sequencing consortium (Nature 2000) 2 3 4
  3. Identification of a novel mutation in RIPK4 in a kindred with phenotypic features of Bartsocas-Papas and CHAND syndromes. (PMID: 26129644) Gollasch B … Betz RC (American journal of medical genetics. Part A 2015) 3 4
  4. Exome sequence identifies RIPK4 as the Bartsocas-Papas syndrome locus. (PMID: 22197488) Mitchell K … Dixon MJ (American journal of human genetics 2012) 3 4
  5. cIAP1/2 are direct E3 ligases conjugating diverse types of ubiquitin chains to receptor interacting proteins kinases 1 to 4 (RIP1-4). (PMID: 21931591) Bertrand MJ … Vandenabeele P (PloS one 2011) 3 4

Products for RIPK4 Gene

Sources for RIPK4 Gene