Free for academic non-profit institutions. Other users need a Commercial license
RIOX1 (Ribosomal Oxygenase 1) is a Protein Coding gene. Diseases associated with RIOX1 include Progressive Myoclonus Epilepsy 7 and Lung Cancer. Among its related pathways are Chromatin Regulation / Acetylation. An important paralog of this gene is RIOX2.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005506 | iron ion binding | IEA,ISS | -- |
GO:0005515 | protein binding | IPI | 19927124 |
GO:0016491 | oxidoreductase activity | IEA | -- |
GO:0016706 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors | IEA,ISS | -- |
GO:0032453 | histone demethylase activity (H3-K4 specific) | IEA,ISS | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | ISS | -- |
GO:0005654 | nucleoplasm | IEA | -- |
GO:0005730 | nucleolus | IEA,IDA | -- |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Chromatin Regulation / Acetylation |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006325 | chromatin organization | IEA | -- |
GO:0034720 | histone H3-K4 demethylation | IEA,ISS | -- |
GO:0045668 | negative regulation of osteoblast differentiation | IEA,ISS | -- |
GO:0045892 | negative regulation of transcription, DNA-templated | IEA,ISS | -- |
GO:0055114 | oxidation-reduction process | IEA | -- |
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Dog (Canis familiaris) |
Mammalia | C8H14orf169 30 |
|
||
Cow (Bos Taurus) |
Mammalia | NO66 30 |
|
||
Rat (Rattus norvegicus) |
Mammalia | RGD1307704 30 |
|
||
Mouse (Mus musculus) |
Mammalia | 2410016O06Rik 30 |
|
||
Riox1 17 |
|
||||
Chicken (Gallus gallus) |
Aves | C5H14ORF169 30 |
|
||
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | LOC100488246 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | zgc:162967 30 |
|
||
Dr.4334 30 |
|
||||
African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP001938 30 |
|
||
Fruit Fly (Drosophila melanogaster) |
Insecta | CG2982 30 |
|
||
Sea Vase (Ciona intestinalis) |
Ascidiacea | Cin.4160 30 |
|
SNP ID | Clinical significance and condition | Chr 14 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
768664 | Benign: not provided | 73,491,111(+) | C/A | MISSENSE_VARIANT,INTRON_VARIANT | |
788892 | Benign: not provided | 73,492,604(+) | C/G | SYNONYMOUS_VARIANT,INTRON_VARIANT | |
rs10144469 | - | p.Lys17Arg | |||
rs34970526 | - | p.Gln239His | |||
rs3813563 | - | p.Val364Ala |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv3892561 | CNV | gain | 25118596 |
nsv1035460 | CNV | gain | 25217958 |
nsv510643 | CNV | deletion | 20534489 |
Disorder | Aliases | PubMed IDs |
---|---|---|
progressive myoclonus epilepsy 7 |
|
|
lung cancer |
|
|
familial isolated hypoparathyroidism |
|
|