Aliases for RILPL2 Gene
External Ids for RILPL2 Gene
Previous GeneCards Identifiers for RILPL2 Gene
This gene encodes a protein that contains a rab-interacting lysosomal protein-like domain. This protein may be involved in regulating lysosome morphology. This protein may also be a target for the Hepatitis C virus and assist in viral replication. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
GeneCards Summary for RILPL2 Gene
RILPL2 (Rab Interacting Lysosomal Protein Like 2) is a Protein Coding gene. Diseases associated with RILPL2 include Diarrhea 2, With Microvillus Atrophy and Hepatitis C Virus. Gene Ontology (GO) annotations related to this gene include identical protein binding. An important paralog of this gene is RILPL1.
UniProtKB/Swiss-Prot for RILPL2 Gene
Involved in cell shape and neuronal morphogenesis, positively regulating the establishment and maintenance of dendritic spines. Plays a role in cellular protein transport, including protein transport away from primary cilia. May function via activation of RAC1 and PAK1 (By similarity).