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Aliases for RILPL1 Gene
Aliases for RILPL1 Gene
External Ids for RILPL1 Gene
- HGNC: 26814
- Entrez Gene: 353116
- Ensembl: ENSG00000188026
- OMIM: 614092
- UniProtKB: Q5EBL4
Previous GeneCards Identifiers for RILPL1 Gene
- GC12M122522
- GC12M123955
- GC12M120917
Summaries for RILPL1 Gene
GeneCards Summary for RILPL1 Gene
RILPL1 (Rab Interacting Lysosomal Protein Like 1) is a Protein Coding gene. Diseases associated with RILPL1 include Epidermolysis Bullosa Simplex, Ogna Type and Alzheimer Disease 3. An important paralog of this gene is RILP.
UniProtKB/Swiss-Prot Summary for RILPL1 Gene
-
Plays a role in the regulation of cell shape and polarity (By similarity). Plays a role in cellular protein transport, including protein transport away from primary cilia (By similarity). Neuroprotective protein, which acts by sequestring GAPDH in the cytosol and prevent the apoptotic function of GAPDH in the nucleus (By similarity). Competes with SIAH1 for binding GAPDH (By similarity). Does not regulate lysosomal morphology and distribution (PubMed:14668488). Binds to RAB10 following LRRK2-mediated RAB10 phosphorylation which leads to inhibition of ciliogenesis (PubMed:30398148).
Additional gene information for RILPL1 Gene
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for RILPL1 Gene
Genomics for RILPL1 Gene
GeneHancer (GH) Regulatory Elements for RILPL1 Gene
Promoters and enhancers for RILPL1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around RILPL1 on UCSC Golden Path with GeneCards custom track
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for RILPL1
- Top Transcription factor binding sites by QIAGEN in the RILPL1 gene promoter:
-
- AML1a
- AP-4
- c-Myc
- Evi-1
- GCNF
- GCNF-1
- GCNF-2
- HTF
- Max1
Genomic Locations for RILPL1 Gene
Genomic Locations for RILPL1 Gene
- chr12:123,470,054-123,533,719
- (GRCh38/hg38)
- Size:
- 63,666 bases
- Orientation:
- Minus strand
- chr12:123,955,909-124,018,265
- (GRCh37/hg19)
- Size:
- 62,357 bases
- Orientation:
- Minus strand
Genomic View for RILPL1 Gene
Genes around RILPL1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 12q24.31 by HGNC
- 12q24.31 by Entrez Gene
- 12q24.31 by Ensembl
RILPL1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for RILPL1 Gene
Proteins for RILPL1 Gene
-
Protein details for RILPL1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q5EBL4-RIPL1_HUMAN
- Recommended name:
- RILP-like protein 1
- Protein Accession:
- Q5EBL4
- Q66K36
- Q8N1M0
Protein attributes for RILPL1 Gene
- Size:
- 403 amino acids
- Molecular mass:
- 47108 Da
- Quaternary structure:
-
- Interacts (when S-nitrosylated) with GAPDH (By similarity). Interacts with RAB8A; interaction is dependent on the phosphorylation of 'Thr-72' of RAB8A (PubMed:29125462, PubMed:30398148). Interacts with RAB10 and RAB12; the interaction is dependent on the phosphorylation of 'Thr-73' of RAB10, and 'Ser-105' of RAB12 (PubMed:29125462, PubMed:30398148).
Protein Expression for RILPL1 Gene
Post-translational modifications for RILPL1 Gene
- S-nitrosylation is required for the interaction with GAPDH.
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for RILPL1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- LifeSpan BioSciences RILPL1 Antibody
- Creative Diagnostics Anti-RILPL1 monoclonal antibody
-
Custom Antibody ServicesOriGene Antibodies for RILPL1
- Novus Biologicals Antibodies for RILPL1
- Invitrogen Antibodies for RILPL1 (AFLGC-RILPL1)
-
Biorbyt antibodies for RILPL1
-
Custom Antibody ServicesProSci Antibodies for RILPL1
Protein Products
-
OriGene Purified Proteins for RILPL1
- Search Origene for MassSpec and Protein Over-expression Lysates for RILPL1
- Origene Custom Protein Services for RILPL1
- antibodies-online: Show 9 available RILPL1 Proteins ranked by validation data
- Compare Top RILPL1 Proteins
-
Quality Products:
-
Abcam proteins for RILPL1
No data available for DME Specific Peptides for RILPL1 Gene
Domains & Families for RILPL1 Gene
Gene Families for RILPL1 Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for RILPL1 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for RILPL1 Gene
- GenScript: Design optimal peptide antigens:
-
- Rab-interacting lysosomal-like protein 1 (RIPL1_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q5EBL4- Family:
-
- Belongs to the RILPL family.
Function for RILPL1 Gene
Molecular function for RILPL1 Gene
- UniProtKB/Swiss-Prot Function:
- Plays a role in the regulation of cell shape and polarity (By similarity). Plays a role in cellular protein transport, including protein transport away from primary cilia (By similarity). Neuroprotective protein, which acts by sequestring GAPDH in the cytosol and prevent the apoptotic function of GAPDH in the nucleus (By similarity). Competes with SIAH1 for binding GAPDH (By similarity). Does not regulate lysosomal morphology and distribution (PubMed:14668488). Binds to RAB10 following LRRK2-mediated RAB10 phosphorylation which leads to inhibition of ciliogenesis (PubMed:30398148).
Phenotypes From GWAS Catalog for RILPL1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 29125462 |
| GO:0031267 | small GTPase binding | IBA | 21873635 |
| GO:0046983 | protein dimerization activity | IEA | -- |
| GO:0051959 | dynein light intermediate chain binding | IBA | 21873635 |
Phenotypes for RILPL1 Gene
- MGI mutant phenotypes for RILPL1:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for RILPL1:
Animal Models for RILPL1 Gene
- MGI Knock Outs for RILPL1:
-
- Rilpl1 Rilpl1<tm1b(EUCOMM)Hmgu>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for RILPL1 - Select products 50% OFF >
- * RILPL1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for RILPL1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RILPL1
- genomics-online: gRNA clones - Search results for available RILPL1 gene related products
-
Santa Cruz Biotechnology (SCBT) CRISPR for RILPL1
miRNA for RILPL1 Gene
- miRTarBase miRNAs that target RILPL1
-
- hsa-mir-7703 (MIRT455112)
- hsa-mir-4793-3p (MIRT455113)
- hsa-mir-766-3p (MIRT455114)
- hsa-mir-1273g-3p (MIRT455115)
- hsa-mir-508-5p (MIRT455116)
- hsa-mir-548ao-3p (MIRT455117)
- hsa-mir-7977 (MIRT671597)
- hsa-mir-24-3p (MIRT671598)
- hsa-mir-4284 (MIRT671599)
- hsa-mir-342-3p (MIRT671600)
- hsa-mir-5693 (MIRT671601)
- hsa-mir-383-3p (MIRT671602)
- hsa-mir-3681-3p (MIRT671603)
- hsa-mir-216a-3p (MIRT671604)
- hsa-mir-128-3p (MIRT671605)
- hsa-mir-1228-3p (MIRT671606)
- hsa-mir-449b-3p (MIRT671607)
- hsa-mir-4298 (MIRT676791)
- hsa-mir-1302 (MIRT676792)
- hsa-mir-6869-5p (MIRT676793)
- hsa-mir-4279 (MIRT676794)
- hsa-mir-1200 (MIRT676795)
- hsa-mir-6829-3p (MIRT676796)
- hsa-mir-6791-3p (MIRT676797)
- hsa-mir-1976 (MIRT676798)
- hsa-mir-3653-5p (MIRT676799)
- hsa-mir-6747-3p (MIRT676800)
- hsa-mir-6727-3p (MIRT676801)
- hsa-mir-4722-3p (MIRT676802)
- hsa-mir-544b (MIRT676803)
- hsa-mir-4324 (MIRT676804)
- hsa-mir-660-3p (MIRT676805)
- hsa-mir-6516-5p (MIRT713490)
- hsa-mir-455-3p (MIRT713491)
- hsa-mir-6807-5p (MIRT713492)
- hsa-mir-25-5p (MIRT713493)
- hsa-mir-658 (MIRT713494)
- hsa-mir-6086 (MIRT713495)
- hsa-mir-6499-3p (MIRT713496)
- hsa-mir-377-5p (MIRT713497)
- hsa-mir-1227-3p (MIRT761407)
- hsa-mir-1247-3p (MIRT761562)
- hsa-mir-1262 (MIRT761711)
- hsa-mir-2467-3p (MIRT764125)
- hsa-mir-3145-5p (MIRT765000)
- hsa-mir-339-5p (MIRT765677)
- hsa-mir-3667-5p (MIRT766563)
- hsa-mir-3940-3p (MIRT767852)
- hsa-mir-4252 (MIRT768035)
- hsa-mir-4257 (MIRT768163)
- hsa-mir-4421 (MIRT768840)
- hsa-mir-4701-3p (MIRT771321)
- hsa-mir-4725-5p (MIRT771640)
- hsa-mir-4797-5p (MIRT772527)
- hsa-mir-490-3p (MIRT772739)
- hsa-mir-542-3p (MIRT773971)
- hsa-mir-550b-2-5p (MIRT774615)
- hsa-mir-5699-3p (MIRT775187)
- hsa-mir-6736-5p (MIRT778072)
- hsa-mir-6742-3p (MIRT778150)
- hsa-mir-6776-5p (MIRT778760)
- hsa-mir-6828-5p (MIRT779959)
- hsa-mir-7851-3p (MIRT782230)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for RILPL1
- Browse OriGene Inhibitory RNA Products For RILPL1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RILPL1
- genomics-online: shRNA clones - Search results for available RILPL1 gene related products
Clone Products
- Applied Biological Materials (abm): Clones for RILPL1 - Select products 50% OFF >
- * RILPL1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for RILPL1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RILPL1
- genomics-online: cdna clones - Search results for available RILPL1 gene related products
- orf clones - Search results for available RILPL1 gene related products
Cell Line Products
-
Horizon Cell Lines for RILPL1
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for RILPL1 Gene
Localization for RILPL1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for RILPL1 Gene
- Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 5 |
| plasma membrane | 4 |
| cytoskeleton | 4 |
| extracellular | 1 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| lysosome | 1 |
- Cytosol (2)
- Nucleoplasm (2)
- Plasma membrane (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005654 | nucleoplasm | IDA | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005813 | centrosome | IEA,ISS | -- |
| GO:0005814 | centriole | IEA | -- |
| GO:0005829 | cytosol | ISS,IDA | -- |
Pathways & Interactions for RILPL1 Gene
Interacting Proteins for RILPL1 Gene
Selected Interacting proteins:
Q5EBL4-RIPL1_HUMAN
ENSP00000366070
for RILPL1 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for RILPL1
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003382 | epithelial cell morphogenesis | ISS | -- |
| GO:0015031 | protein transport | IEA | -- |
| GO:1901214 | regulation of neuron death | ISS,IEA | -- |
| GO:1903445 | protein transport from ciliary membrane to plasma membrane | ISS,IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for RILPL1 Gene
Transcripts for RILPL1 Gene
mRNA/cDNA for RILPL1 Gene
- 4 REFSEQ mRNAs :
- 6 NCBI additional mRNA sequence :
- 5 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000340724 2389 bps (ENST00000340724.6)
- ENST00000376874 3933 bps (ENST00000376874.9)
- ENST00000544468 769 bps (ENST00000544468.1)
- ENST00000623184 3894 bps (ENST00000623184.1)
- ENST00000636882 2258 bps (ENST00000636882.1)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for RILPL1 - Select products 50% OFF >
- * RILPL1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for RILPL1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RILPL1
- genomics-online: gRNA clones - Search results for available RILPL1 gene related products
-
Santa Cruz Biotechnology (SCBT) CRISPR for RILPL1
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for RILPL1
- Browse OriGene Inhibitory RNA Products For RILPL1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RILPL1
- genomics-online: shRNA clones - Search results for available RILPL1 gene related products
Clone Products
- Applied Biological Materials (abm): Clones for RILPL1 - Select products 50% OFF >
- * RILPL1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for RILPL1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RILPL1
- genomics-online: cdna clones - Search results for available RILPL1 gene related products
- orf clones - Search results for available RILPL1 gene related products
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | |||||||||||||||||||||||||
| SP2: | - | - | - | - | - | ||||||||||||||||||||||||
| SP3: | - | - | - | ||||||||||||||||||||||||||
| SP4: | - | ||||||||||||||||||||||||||||
| SP5: | |||||||||||||||||||||||||||||
| SP6: | - |
Relevant External Links for RILPL1 Gene
- GeneLoc Exon Structure for
- RILPL1
Expression for RILPL1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
mRNA differential expression in normal tissues according to GTEx for RILPL1 Gene
This gene is overexpressed in Heart - Left Ventricle (x4.7) and Heart - Atrial Appendage (x4.4).
This gene is overexpressed in Bone marrow stromal cell (16.9) and Urinary Bladder (6.7).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for RILPL1 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for RILPL1
SOURCE GeneReport for Unigene cluster for RILPL1 Gene:
Hs.530315mRNA Expression by UniProt/SwissProt for RILPL1 Gene:
Q5EBL4-RIPL1_HUMAN
Tissue specificity:
Widely expressed. Expressed at lower level in liver and kidney.
Evidence on tissue expression from TISSUES for RILPL1 Gene
- Nervous system(4.3)
- Liver(4.1)
- Eye(3.2)
Primer Products
-
OriGene qPCR primer pairs for RILPL1
-
OriGene qPCR primer pairs and template standards for RILPL1
- genomics-online: primer clones - Search results for available RILPL1 gene related products
Gene Expression Assay Products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for RILPL1 Gene
Orthologs for RILPL1 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | RILPL1 31 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | RILPL1 31 30 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | RILPL1 31 30 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Rilpl1 17 31 30 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Rilpl1 30 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
| -- 31 |
|
OneToMany | |||
| oppossum (Monodelphis domestica) |
Mammalia | RILPL1 31 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | gga-mir-7476 31 |
|
OneToOne | |
| RILPL1 30 |
|
||||
| lizard (Anolis carolinensis) |
Reptilia | RILPL1 31 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | rilpl1 30 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.2738 30 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | rilpl1 31 30 |
|
OneToOne | |
| fruit fly (Drosophila melanogaster) |
Insecta | CG11448 31 30 |
|
OneToMany | |
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP005040 30 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | rilp-1 31 30 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.2252 31 |
|
OneToMany |
- Species where no ortholog for RILPL1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Evolution for RILPL1 Gene
- ENSEMBL:
- Gene Tree for RILPL1 (if available)
- TreeFam:
- Gene Tree for RILPL1 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for RILPL1: view image
Paralogs for RILPL1 Gene
Variants for RILPL1 Gene
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv886n106 | CNV | deletion | 24896259 |
| dgv927e59 | CNV | duplication | 20981092 |
| esv1489716 | CNV | deletion | 17803354 |
| esv2422416 | CNV | duplication | 17116639 |
| esv24540 | CNV | gain | 19812545 |
| esv2746507 | CNV | deletion | 23290073 |
| esv2746509 | CNV | deletion | 23290073 |
| esv3409514 | CNV | duplication | 20981092 |
| esv3630989 | CNV | loss | 21293372 |
| nsv1037260 | CNV | gain | 25217958 |
| nsv1070139 | CNV | deletion | 25765185 |
| nsv1122778 | CNV | deletion | 24896259 |
| nsv1124664 | CNV | duplication | 24896259 |
| nsv1142819 | CNV | tandem duplication | 24896259 |
| nsv1150664 | CNV | duplication | 26484159 |
| nsv560495 | CNV | loss | 21841781 |
| nsv952499 | CNV | deletion | 24416366 |
Residual Variation Intolerance Score:
52% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.49;
29.10% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for RILPL1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- RILPL1
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for RILPL1 Gene
Disorders for RILPL1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| epidermolysis bullosa simplex, ogna type |
|
|
| alzheimer disease 3 |
|
|
| paraphilia disorder |
|
|
| pedophilia |
|
|
| drug psychosis |
|
|
Search RILPL1 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for RILPL1
- Genetic Association Database
- (GAD)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for RILPL1 Gene
Publications for RILPL1 Gene
- A unique region of RILP distinguishes it from its related proteins in its regulation of lysosomal morphology and interaction with Rab7 and Rab34. (PMID: 14668488) Wang T … Hong W (Molecular biology of the cell 2004) 2 3 4 54
- Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis. (PMID: 29125462) Steger M … Mann M (eLife 2017) 3 4 54
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 54
- A pathway for Parkinson's Disease LRRK2 kinase to block primary cilia and Sonic hedgehog signaling in the brain. (PMID: 30398148) Dhekne HS … Pfeffer SR (eLife 2018) 4 54
- Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. (PMID: 28611215) Fei T … Brown M (Proceedings of the National Academy of Sciences of the United States of America 2017) 3 54
ExternalLinks
Products for RILPL1 Gene
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- Custom Assay Services
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- Search Origene for MassSpec and Protein Over-expression Lysates for RILPL1
- Origene Custom Protein Services for RILPL1
- Origene shrna, sirna, and RNAi products in human, mouse, rat for RILPL1
- Browse OriGene Inhibitory RNA Products For RILPL1
- OriGene qPCR primer pairs for RILPL1
- OriGene qPCR primer pairs and template standards for RILPL1
- OriGene CRISPR knockouts for RILPL1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For RILPL1
- Sino Biological Human cDNA Clone for RILPL1
- Browse Sino Biological Recombinant Proteins
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- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
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- Novus Biologicals Antibodies for RILPL1
- Novus Biologicals proteins and lysates for RILPL1
- Browse Antibodies
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- Invitrogen Antibodies for RILPL1 (AFLGC-RILPL1)
- VectorBuilder Custom and pre-made DNA vectors for RILPL1 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for RILPL1 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for RILPL1 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for RILPL1 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for RILPL1
- antibodies-online: Show 10 available RILPL1 Antibodies ranked by validation data
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- antibodies-online: Search results for available RILPL1 related products ranked by validation data
- antibodies-online: Show 9 available RILPL1 Proteins ranked by validation data
- Compare Top RILPL1 Proteins
- Quality Products:
- Custom Antibody ServicesProSci Antibodies for RILPL1
- Search for RILPL1 Proteins at ProSci
- Horizon Cell Lines for RILPL1
- genomics-online: cdna clones - Search results for available RILPL1 gene related products
- orf clones - Search results for available RILPL1 gene related products
- genomics-online: gRNA clones - Search results for available RILPL1 gene related products
- genomics-online: primer clones - Search results for available RILPL1 gene related products
- genomics-online: shRNA clones - Search results for available RILPL1 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RILPL1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RILPL1
- Search GeneCopoeia for miRNA 3'UTR Target clone products for RILPL1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RILPL1
- Biorbyt antibodies for RILPL1
Sources for RILPL1 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) H-invDB
- (47) HORDE
- (48) HUGE
- (49) IMGT
- (50) Leiden
- (51) miRBase
- (52) DME
- (53) OriGene
- (54) PubMed
- (55) R&D Systems
- (56) TGDB
- (57) Tocris
- (58) Abcam
- (59) Novus Biologicals
- (60) ProSpec
- (61) Sino Biological
- (62) GenScript
- (63) Qiagen
- (64) OCA
- (65) Proteopedia
- (66) MOPED
- (67) neXtProt
- (68) Reactome
- (69) GeneGo (Thomson Reuters)
- (70) DISEASES
- (71) SIMAP
- (72) GenomeRNAi
- (73) LifeMap
- (74) miRTarBase
- (75) MalaCards
- (76) Invitrogen
- (77) BitterDB
- (78) ESI-BIO
- (79) RefSeq
- (80) BioSystems
- (81) MaxQB
- (82) IUPHAR
- (83) BioGPS
- (84) Illumina
- (85) COMPARTMENTS
- (86) HOMER
- (87) PaxDb
- (88) ApexBio
- (89) Addgene
- (90) antibodies-online
- (91) CYP
- (92) NONCODE
- (93) TreeFam
- (94) PathCards
- (95) GeneReviews
- (96) GeneTex
- (97) Taconic Biosciences
- (98) GTEx
- (99) ProteomicsDB
- (100) SCBT
- (101) DGIdb
- (102) ClinicalTrials
- (103) RVIS
- (104) SIGNOR
- (105) diseasecard
- (106) NIH Rare Diseases
- (107) Orphanet
- (108) UMLS
- (109) GTR
- (110) Disease Ontology
- (111) Genetics Home Reference
- (112) MeSH
- (113) MedlinePlus
- (114) CDC
- (115) NINDS
- (116) NCBI Bookshelf
- (117) ClinVar
- (118) Gene Damage Index
- (119) HPO
- (120) UDN
- (121) VISTA
- (122) FANTOM5
- (123) ENCODE
- (124) ProSci
- (125) Horizon
- (126) The Signaling Pathways Project (SPP)
- (127) IID
- (128) VectorBuilder
- (129) SNPedia
- (130) BRCA Exchange
- (131) CIViC
- (132) ProteoGenix
- (133) dbSUPER
- (134) TISSUES
- (135) Gene ORGANizer
- (136) abm
- (137) Human Protein Atlas
- (138) GWAS Catalog
- (139) Monarch Initiative
- (140) DataMed
- (141) HumanCyc
- (142) genomics-online
- (143) UCNEbase
- (144) EPDnew
- (145) Applied Biosystems
- (146) GlyConnect
- (147) Aminode
- (148) GeneCopoeia
- (149) GPS-Prot
- (150) RNACentral
- (151) LncRNADisease
- (152) LOVD
- (153) miR2Disease
- (154) DiseaseEnhancer
- (155) Boster Bio
- (156) Biorbyt
- (157) Biocompare
- (158) Mastermind
- (159) CTD^2 Dashboard
- (160) CraniofacialAtlas
- (161) GeneImprint
- (162) Synthego
- (163) Bio Basic
- (164) ENA
- (165) GtRNAdb
- (166) LncBase
- (167) LncBook
- (168) LNCipedia
- (169) LncRNAdb
- (170) Modomics
- (171) PDBe
- (172) Rfam
- (173) SILVA
- (174) snOPY
- (175) SRPDB
- (176) GENCODE
- (177) TarBase
- (178) MyBioSource
- (179) Signalway Antibody