Aliases for RILPL1 Gene
Rab Interacting Lysosomal Protein Like 1
RILP-Like Protein 1 3
GAPDH Competitor Of SIAH Protein Enhances Life 3
Rab-Interacting Lysosomal-Like Protein 1 4
External Ids for RILPL1 Gene
Previous GeneCards Identifiers for RILPL1 Gene
RILPL1 (Rab Interacting Lysosomal Protein Like 1) is a Protein Coding gene.
Diseases associated with RILPL1 include Alzheimer Disease 3.
An important paralog of this gene is RILP.
Plays a role in the regulation of cell shape and polarity (By similarity). Plays a role in cellular protein transport, including protein transport away from primary cilia (By similarity). Neuroprotective protein, which acts by sequestring GAPDH in the cytosol and prevent the apoptotic function of GAPDH in the nucleus (By similarity). Competes with SIAH1 for binding GAPDH (By similarity). Does not regulate lysosomal morphology and distribution (PubMed:14668488). Binds to RAB10 following LRRK2-mediated RAB10 phosphorylation which leads to inhibition of ciliogenesis (PubMed:30398148).
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for RILPL1 Gene