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This gene encodes a member of the rhophilin family of Ras-homologous (Rho)-GTPase binding proteins. The encoded protein binds both GTP- and GDP-bound RhoA and GTP-bound RhoB and may be involved in the organization of the actin cytoskeleton. [provided by RefSeq, Apr 2009] See more...
Aliases for RHPN2 Gene
Aliases for RHPN2 Gene
External Ids for RHPN2 Gene
- HGNC: 19974
- Entrez Gene: 85415
- Ensembl: ENSG00000131941
- OMIM: 617932
- UniProtKB: Q8IUC4
Previous GeneCards Identifiers for RHPN2 Gene
- GC19M033918
- GC19M038145
- GC19M038161
- GC19M033469
- GC19M029972
Summaries for RHPN2 Gene
-
This gene encodes a member of the rhophilin family of Ras-homologous (Rho)-GTPase binding proteins. The encoded protein binds both GTP- and GDP-bound RhoA and GTP-bound RhoB and may be involved in the organization of the actin cytoskeleton. [provided by RefSeq, Apr 2009]
GeneCards Summary for RHPN2 Gene
RHPN2 (Rhophilin Rho GTPase Binding Protein 2) is a Protein Coding gene. Diseases associated with RHPN2 include Hereditary Mixed Polyposis Syndrome. Among its related pathways are Signaling by GPCR and Actin Nucleation by ARP-WASP Complex. An important paralog of this gene is RHPN1.
UniProtKB/Swiss-Prot Summary for RHPN2 Gene
-
Binds specifically to GTP-Rho. May function in a Rho pathway to limit stress fiber formation and/or increase the turnover of F-actin structures in the absence of high levels of RhoA activity.
Additional gene information for RHPN2 Gene
- HGNC(19974)
- Entrez Gene(85415)
- Ensembl(ENSG00000131941)
- OMIM(617932)
- UniProtKB(Q8IUC4)
- Open Targets Platform(ENSG00000131941)
- Monarch Initiative
- Search for RHPN2 at DataMed
- Search for RHPN2 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for RHPN2 Gene
Genomics for RHPN2 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for RHPN2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around RHPN2 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for RHPN2
- Top Transcription factor binding sites by QIAGEN in the RHPN2 gene promoter:
-
- GCNF
- GCNF-1
- GCNF-2
- GR-alpha
- GR-beta
- LCR-F1
- Pax-4a
- Pax-5
- Sox5
- SRY
Genomic Locations for RHPN2 Gene
Genomic Locations for RHPN2 Gene
- chr19:32,978,592-33,064,888
- (GRCh38/hg38)
- Size:
- 86,297 bases
- Orientation:
- Minus strand
- chr19:33,469,498-33,555,824
- (GRCh37/hg19)
- Size:
- 86,327 bases
- Orientation:
- Minus strand
Genomic View for RHPN2 Gene
Genes around RHPN2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19q13.11 by HGNC
- 19q13.11 by Entrez Gene
- 19q13.11 by Ensembl
RHPN2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for RHPN2 Gene
Proteins for RHPN2 Gene
-
Protein details for RHPN2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8IUC4-RHPN2_HUMAN
- Recommended name:
- Rhophilin-2
- Protein Accession:
- Q8IUC4
- B2RCG8
- B3KUY8
- B4DUS7
- Q8N3T7
- Q8N9D6
- Q8NE33
- Q96RU1
Protein attributes for RHPN2 Gene
- Size:
- 686 amino acids
- Molecular mass:
- 76993 Da
- Quaternary structure:
-
- Interacts with GTP-bound RhoA and RhoB. Interacts with both GTP- and GDP-bound RhoA. According to PubMed:12473120, it does not interact with RhoA. Interacts with KRT18.
Protein Expression for RHPN2 Gene
Post-translational modifications for RHPN2 Gene
Other Protein References for RHPN2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Creative Diagnostics Anti-RHPN2 monoclonal antibody
- Creative Biolabs Mouse Anti-RHPN2 Recombinant Antibody (1C5)
-
Custom Antibody ServicesOriGene Antibodies for RHPN2
- Novus Biologicals Antibodies for RHPN2
- Invitrogen Antibodies for RHPN2 (AFLGC-RHPN2)
-
Boster Bio Antibodies for RHPN2
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for RHPN2
- Origene Custom Protein Services for RHPN2
- antibodies-online: Show 5 available RHPN2 Proteins ranked by validation data
- Compare Top RHPN2 Proteins
-
Quality Products:
-
Abcam proteins for RHPN2
No data available for DME Specific Peptides for RHPN2 Gene
Domains & Families for RHPN2 Gene
Gene Families for RHPN2 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for RHPN2 Gene
- InterPro:
- Blocks:
-
- PDZ/DHR/GLGF domain
- Protein kinase PKN/PRK1, effector
- BRO1-like domain
- ProtoNet:
Suggested Antigen Peptide Sequences for RHPN2 Gene
- GenScript: Design optimal peptide antigens:
-
- cDNA FLJ44542 fis, clone UTERU3005585, highly similar to Rhophilin-2 (B3KX27_HUMAN)
- p76RBE (RHPN2_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q8IUC4- Family:
-
- Belongs to the RHPN family.
Function for RHPN2 Gene
Molecular function for RHPN2 Gene
- UniProtKB/Swiss-Prot Function:
- Binds specifically to GTP-Rho. May function in a Rho pathway to limit stress fiber formation and/or increase the turnover of F-actin structures in the absence of high levels of RhoA activity.
- UniProtKB/Swiss-Prot Induction:
- By thyrotropin (TSH). Regulated by the cAMP pathway.
Phenotypes From GWAS Catalog for RHPN2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IEA | -- |
Phenotypes for RHPN2 Gene
- MGI mutant phenotypes for RHPN2:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for RHPN2:
-
- Decreased hepcidin::fluc mRNA expression
- Increased vaccinia virus (VACV) infection
- Mildly decreased CFP-tsO45G cell surface transport
- no effect
- Decreased vaccinia virus (VACV) infection
- shRNA abundance <= 50%
- Increased G1 DNA content
- shRNA abundance <= 25%
- Increased transferrin (TF) endocytosis
- Decreased shRNA abundance (Z-score < -2)
- Increased shRNA abundance (Z-score > 2)
- G0/1 arrest
Animal Models for RHPN2 Gene
- MGI Knock Outs for RHPN2:
-
- Rhpn2 Rhpn2<tm1Ssch>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for RHPN2 - Select products 50% OFF >
- * RHPN2 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for RHPN2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RHPN2
-
Santa Cruz Biotechnology (SCBT) CRISPR for RHPN2
miRNA for RHPN2 Gene
- miRTarBase miRNAs that target RHPN2
-
- mmu-miR-124-3p (MIRT015905)
- hsa-miR-32-5p (MIRT028291)
- hsa-miR-100-5p (MIRT048413)
- mmu-miR-3087-3p (MIRT597449)
- mmu-miR-1264-3p (MIRT597450)
- mmu-miR-290a-5p (MIRT597451)
- mmu-miR-292a-5p (MIRT597452)
- mmu-miR-3073a-5p (MIRT604745)
- hsa-miR-1273g-3p (MIRT761981)
- hsa-miR-1285-3p (MIRT762217)
- hsa-miR-196a-3p (MIRT763511)
- hsa-miR-3120-3p (MIRT764780)
- hsa-miR-3187-5p (MIRT765320)
- hsa-miR-451b (MIRT769957)
- hsa-miR-4696 (MIRT771263)
- hsa-miR-4793-3p (MIRT772427)
- hsa-miR-508-5p (MIRT773188)
- hsa-miR-5189-5p (MIRT773570)
- hsa-miR-612 (MIRT775861)
- hsa-miR-6512-3p (MIRT776941)
- hsa-miR-661 (MIRT777457)
- hsa-miR-6720-5p (MIRT777787)
- hsa-miR-6849-3p (MIRT780338)
- hsa-miR-6860 (MIRT780569)
- hsa-miR-766-3p (MIRT781897)
- hsa-miR-7703 (MIRT782051)
- hsa-miR-939-3p (MIRT782836)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for RHPN2
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Clone Products
- Applied Biological Materials (abm): Clones for RHPN2 - Select products 50% OFF >
- * RHPN2 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for RHPN2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RHPN2
Cell Line Products
-
Horizon Cell Lines for RHPN2
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for RHPN2 Gene
Localization for RHPN2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for RHPN2 Gene
- Cytoplasm, perinuclear region.
| Compartment | Confidence |
|---|---|
| cytosol | 4 |
| cytoskeleton | 2 |
| nucleus | 2 |
| plasma membrane | 1 |
| extracellular | 1 |
| mitochondrion | 1 |
| endosome | 1 |
| peroxisome | 0 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005829 | cytosol | TAS | -- |
| GO:0048471 | perinuclear region of cytoplasm | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for RHPN2 Gene
Pathways & Interactions for RHPN2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Signaling by Rho GTPases | ||
| 2 | Actin Nucleation by ARP-WASP Complex |
RhoA Pathway
.35
|
|
| 3 | RHO GTPases Activate Rhotekin and Rhophilins | ||
| 4 | Signaling by GPCR | ||
| 5 | G-protein signaling_RhoB regulation pathway |
G-protein signaling_RhoB regulation pathway
-
|
|
Pathways by source for RHPN2 Gene
1 BioSystems pathway for RHPN2 Gene
4 Reactome pathways for RHPN2 Gene
1 GeneGo (Thomson Reuters) pathway for RHPN2 Gene
- G-protein signaling_RhoB regulation pathway
1 Qiagen pathway for RHPN2 Gene
- RhoA Pathway
Interacting Proteins for RHPN2 Gene
Selected Interacting proteins:
Q8IUC4-RHPN2_HUMAN
ENSP00000254260
for RHPN2 Gene via
MINT
STRING
IID
GPS-Prot Interaction Network for RHPN2
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007165 | signal transduction | IEA | -- |
No data available for SIGNOR curated interactions for RHPN2 Gene
Transcripts for RHPN2 Gene
mRNA/cDNA for RHPN2 Gene
- 1 REFSEQ mRNAs :
- 12 NCBI additional mRNA sequence :
- 7 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000254260 3501 nts (view in UCSC)
- ENST00000544458 3793 nts (view in UCSC)
- ENST00000585641 468 nts (view in UCSC)
- ENST00000588388 2378 nts (view in UCSC)
- ENST00000588683 706 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for RHPN2 - Select products 50% OFF >
- * RHPN2 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for RHPN2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RHPN2
-
Santa Cruz Biotechnology (SCBT) CRISPR for RHPN2
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for RHPN2
- Browse OriGene Inhibitory RNA Products For RHPN2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RHPN2
Clone Products
- Applied Biological Materials (abm): Clones for RHPN2 - Select products 50% OFF >
- * RHPN2 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for RHPN2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RHPN2
Relevant External Links for RHPN2 Gene
- GeneLoc Exon Structure for
- RHPN2
Expression for RHPN2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Kidney (Urinary System)
- Ureteric Bud Cells Ureteric Bud
- Ureteric Bud Tip Cells Ureteric Bud
-
Brain (Nervous System)
- Myelinating Oligodendrocyte Cells Forebrain White Matter
- Adult Endothelial Cells Blood Brain Barrier
-
Blood (Hematopoietic System)
- Mature B-Cells Peripheral Blood
- Hematopoietic Stem Cells Hematopoietic Bone Marrow
-
Glial Cells
- Myelinating Oligodendrocyte Cells Forebrain White Matter
-
Tooth (Integumentary System)
- Dental Placode Cells Dental Placode
-
Epithelial Cells
- Dental Placode Cells Dental Placode
-
Endothelium (Cardiovascular System)
- Adult Endothelial Cells Blood Brain Barrier
This gene is overexpressed in Salivary gland (22.5), Stomach (17.4), Islet of Langerhans (11.1), and Retina (8.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for RHPN2 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for RHPN2
SOURCE GeneReport for Unigene cluster for RHPN2 Gene:
Hs.466435mRNA Expression by UniProt/SwissProt for RHPN2 Gene:
Q8IUC4-RHPN2_HUMAN
Tissue specificity:
Widely expressed. Highly expressed in prostate, trachea, stomach, colon, thyroid and pancreas. Expressed at lower level in brain, spinal cord, kidney, placenta and liver.
Evidence on tissue expression from TISSUES for RHPN2 Gene
- Nervous system(4.5)
- Kidney(4.4)
- Liver(4.3)
- Intestine(2.5)
Primer Products
-
OriGene qPCR primer pairs for RHPN2
-
OriGene qPCR primer pairs and template standards for RHPN2
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for RHPN2 Gene
Orthologs for RHPN2 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | RHPN2 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | RHPN2 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | RHPN2 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Rhpn2 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Rhpn2 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | RHPN2 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | RHPN2 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | RHPN2 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | RHPN2 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | rhpn2 30 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.2712 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | rhpn2 30 31 |
|
OneToOne | |
| zgc55960 30 |
|
||||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP000243 30 |
|
||
| Fruit Fly (Drosophila melanogaster) |
Insecta | Rhp 30 31 |
|
OneToMany | |
| Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | RIM20 31 |
|
OneToMany | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
- Species where no ortholog for RHPN2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for RHPN2 Gene
- ENSEMBL:
- Gene Tree for RHPN2 (if available)
- TreeFam:
- Gene Tree for RHPN2 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for RHPN2: view image
Paralogs for RHPN2 Gene
(2) SIMAP similar genes for RHPN2 Gene using alignment to 3 proteins:
- RHPN2_HUMAN
- B4DUS7_HUMAN
- K7EL35_HUMAN
Pseudogenes.org Pseudogenes for RHPN2 Gene
Variants for RHPN2 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for RHPN2 Gene
| SNP ID | Clinical significance and condition | Chr 19 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 761865 | Likely Benign: not provided | 33,011,807(-) | C/T | INTRON_VARIANT | |
| 777526 | Benign: not provided | 33,002,328(-) | C/G | MISSENSE_VARIANT | |
| 779185 | Benign: not provided | 33,002,929(-) | C/T | MISSENSE_VARIANT | |
| 791356 | Benign: not provided | 32,996,086(-) | A/C | MISSENSE_VARIANT | |
| rs79314177 | Benign: not specified | 32,991,915(-) | G/A | MISSENSE_VARIANT |
Residual Variation Intolerance Score:
97.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
14.95;
96.80% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for RHPN2 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RHPN2 Gene
Disorders for RHPN2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| hereditary mixed polyposis syndrome |
|
|
Search RHPN2 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for RHPN2
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for RHPN2 Gene
Publications for RHPN2 Gene
- The RhoA-binding protein, rhophilin-2, regulates actin cytoskeleton organization. (PMID: 12221077) Peck JW … Burbelo PD (The Journal of biological chemistry 2002) 2 3 4 23
- The utility and predictive value of combinations of low penetrance genes for screening and risk prediction of colorectal cancer. (PMID: 20437058) Hawken SJ … Little J (Human genetics 2010) 3 41
- Genetic heterogeneity in colorectal cancer associations between African and European americans. (PMID: 20659471) Kupfer SS … Ellis NA (Gastroenterology 2010) 3 41
- Low-penetrance susceptibility variants in familial colorectal cancer. (PMID: 20501757) Niittymäki I … Aaltonen LA (Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010) 3 41
- Risk of genome-wide association study-identified genetic variants for colorectal cancer in a Chinese population. (PMID: 20530476) Xiong F … Lin D (Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010) 3 41
ExternalLinks
Products for RHPN2 Gene
- Custom Antibody ServicesOriGene Antibodies for RHPN2
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- Custom Assay Services
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- OriGene qPCR primer pairs for RHPN2
- OriGene qPCR primer pairs and template standards for RHPN2
- OriGene CRISPR knockouts for RHPN2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For RHPN2
- Sino Biological Human cDNA Clone for RHPN2
- Browse Sino Biological Recombinant Proteins
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- Browse Sino Biological Assays
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for RHPN2
- Novus Biologicals proteins and lysates for RHPN2
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam proteins for RHPN2
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for RHPN2 (AFLGC-RHPN2)
- VectorBuilder Custom and pre-made DNA vectors for RHPN2 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for RHPN2 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for RHPN2 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for RHPN2 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for RHPN2
- antibodies-online: Show 12 available RHPN2 Antibodies ranked by validation data
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- antibodies-online: Search results for available RHPN2 related products ranked by validation data
- antibodies-online: Show 5 available RHPN2 Proteins ranked by validation data
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- Quality Products:
- Horizon Cell Lines for RHPN2
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RHPN2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RHPN2
- Search GeneCopoeia for miRNA 3'UTR Target clone products for RHPN2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RHPN2
- Boster Bio Antibodies for RHPN2
- Browse Boster Bio ELISA Kits
Sources for RHPN2 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
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