Aliases for RHOF Gene
External Ids for RHOF Gene
Previous HGNC Symbols for RHOF Gene
Previous GeneCards Identifiers for RHOF Gene
GeneCards Summary for RHOF Gene
RHOF (Ras Homolog Family Member F, Filopodia Associated) is a Protein Coding gene. Diseases associated with RHOF include Charcot-Marie-Tooth Disease, Axonal, Type 2L and Malaria. Among its related pathways are Innate Immune System and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is RHOD.
UniProtKB/Swiss-Prot Summary for RHOF Gene
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Causes the formation of thin, actin-rich surface projections called filopodia. Functions cooperatively with CDC42 and Rac to generate additional structures, increasing the diversity of actin-based morphology.