Aliases for RHNO1 Gene
External Ids for RHNO1 Gene
Previous HGNC Symbols for RHNO1 Gene
Previous GeneCards Identifiers for RHNO1 Gene
GeneCards Summary for RHNO1 Gene
RHNO1 (RAD9-HUS1-RAD1 Interacting Nuclear Orphan 1) is a Protein Coding gene. Diseases associated with RHNO1 include Cavernous Sinus Thrombosis and Intracranial Sinus Thrombosis. Among its related pathways are DNA Double-Strand Break Repair and Gene Expression.
UniProtKB/Swiss-Prot Summary for RHNO1 Gene
Plays a role in DNA damage response (DDR) signaling upon genotoxic stresses such as ionizing radiation (IR) during the S phase. Recruited to sites of DNA damage through interaction with the 9-1-1 cell-cycle checkpoint response complex and TOPBP1 in a ATR-dependent manner. Required for the progression of the G1 to S phase transition. Plays a role in the stimulation of CHEK1 phosphorylation.