RHAG Gene (Protein Coding)

Rh Associated Glycoprotein

GC06M049605
GIFtS:
45
The protein encoded by this gene is erythrocyte-specific and is thought to be part of a membrane channel that transports ammonium and carbon dioxide across the blood cell membrane. The encoded protein appears to interact with Rh blood group antigens and Rh30 polypeptides. Defects in this gene are a cause of regulator type Rh-null hemolytic anemia (RHN), or Rh-deficiency syndrom... See more...

Aliases for RHAG Gene

Aliases for RHAG Gene

  • Rh Associated Glycoprotein 2 3 5
  • Rhesus Blood Group-Associated Glycoprotein 2 3 4
  • Ammonium Transporter Rh Type A 2 3 4
  • Erythrocyte Plasma Membrane 50 KDa Glycoprotein 3 4
  • Rhesus Blood Group Family Type A Glycoprotein 3 4
  • Rhesus Blood Group-Associated Ammonia Channel 3 4
  • Erythrocyte Membrane Glycoprotein Rh50 3 4
  • Rh Family Type A Glycoprotein 3 4
  • Rh Type A Glycoprotein 3 4
  • Rhesus Associated Polypeptide, 50-KD 3
  • Truncated Rh-Associated Glycoprotein 3
  • Mutant Rh Associated Glycoprotein 3
  • Truncated RhAG Glycoprotein 3
  • Rh 50 Glycoprotein 3
  • CD241 Antigen 4
  • SLC42A1 3
  • Rh50GP 3
  • CD241 3
  • RH50A 3
  • Rh50A 4
  • OHST 3
  • RHNR 3
  • Rh50 3
  • RH50 4
  • OHS 3
  • RH2 3

External Ids for RHAG Gene

Previous GeneCards Identifiers for RHAG Gene

  • GC06M049574
  • GC06M049619
  • GC06M049680
  • GC06M049302

Summaries for RHAG Gene

Entrez Gene Summary for RHAG Gene

  • The protein encoded by this gene is erythrocyte-specific and is thought to be part of a membrane channel that transports ammonium and carbon dioxide across the blood cell membrane. The encoded protein appears to interact with Rh blood group antigens and Rh30 polypeptides. Defects in this gene are a cause of regulator type Rh-null hemolytic anemia (RHN), or Rh-deficiency syndrome.[provided by RefSeq, Mar 2009]

GeneCards Summary for RHAG Gene

RHAG (Rh Associated Glycoprotein) is a Protein Coding gene. Diseases associated with RHAG include Overhydrated Hereditary Stomatocytosis and Rh-Null, Regulator Type. Among its related pathways are Erythrocytes take up carbon dioxide and release oxygen and Metabolism. Gene Ontology (GO) annotations related to this gene include ankyrin binding and ammonium transmembrane transporter activity. An important paralog of this gene is RHCG.

UniProtKB/Swiss-Prot Summary for RHAG Gene

  • Associated with rhesus blood group antigen expression (PubMed:19744193). May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane (PubMed:11062476, PubMed:11861637). Involved in ammonia transport across the erythrocyte membrane (PubMed:21849667, PubMed:22012326). Seems to act in monovalent cation transport (PubMed:18931342, PubMed:21849667).

Gene Wiki entry for RHAG Gene

Additional gene information for RHAG Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for RHAG Gene

Genomics for RHAG Gene

GeneHancer (GH) Regulatory Elements for RHAG Gene

Promoters and enhancers for RHAG Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH06J049636 Promoter 1.1 EPDnew 500.7 +0.0 25 0.1 ZBTB11 AFF1 TARDBP MYC CTBP1 JUN NFRKB TAF9B LEF1 GTF2F1 RHAG piR-47628-165
GH06J049645 Enhancer 1.3 FANTOM5 Ensembl ENCODE 20.4 -10.2 -10217 3.8 GTF2E2 PHB2 ZBTB11 AFF1 TARDBP REST DNMT1 HES1 MYC CTBP1 RHAG ENSG00000235122 ENSG00000226707 CRISP3 C6orf141 CRISP2 CENPQ lnc-C6orf141-3
GH06J049663 Enhancer 0.6 Ensembl 11.2 -25.9 -25917 0.4 NCOR1 NFRKB CEBPG CEBPB PBX2 JUND GATA3 ADNP MAFG ZNF384 RHAG CRISP3 ENSG00000235122 PGK2 ENSG00000226707 C6orf141 lnc-C6orf141-3 HSALNG0050504
GH06J049662 Enhancer 0.5 Ensembl 11.2 -25.4 -25417 0.2 NCOR1 NFRKB ZNF316 ZNF592 NFE2 MAFG CEBPB ZNF24 HDAC1 EMSY RHAG CRISP3 ENSG00000235122 PGK2 ENSG00000226707 lnc-C6orf141-3 HSALNG0050504
GH06J050116 Enhancer 0.2 Ensembl 5.5 -480.2 -480217 1.4 RHAG LOC100505985 lnc-TFAP2D-4
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around RHAG on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for RHAG

Top Transcription factor binding sites by QIAGEN in the RHAG gene promoter:
  • AP-1
  • ATF-2
  • c-Jun
  • HNF-3beta
  • POU3F2
  • POU3F2 (N-Oct-5a)
  • POU3F2 (N-Oct-5b)
  • PPAR-gamma1
  • PPAR-gamma2

Genomic Locations for RHAG Gene

Genomic Locations for RHAG Gene
chr6:49,605,158-49,636,884
(GRCh38/hg38)
Size:
31,727 bases
Orientation:
Minus strand
chr6:49,572,871-49,604,587
(GRCh37/hg19)
Size:
31,717 bases
Orientation:
Minus strand

Genomic View for RHAG Gene

Genes around RHAG on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RHAG Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RHAG Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for RHAG Gene

Proteins for RHAG Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

  • Protein details for RHAG Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q02094-RHAG_HUMAN
    Recommended name:
    Ammonium transporter Rh type A
    Protein Accession:
    Q02094
    Secondary Accessions:
    • B2R8T8
    • O43514
    • O43515
    • Q7L8L3
    • Q9H454

    Protein attributes for RHAG Gene

    Size:
    409 amino acids
    Molecular mass:
    44198 Da
    Quaternary structure:
    • Heterotetramer.

    Alternative splice isoforms for RHAG Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for RHAG Gene

Protein Expression for RHAG Gene

See protein expression from ProteomicsDB, MOPED, PaxDb, and MaxQB

Post-translational modifications for RHAG Gene

Other Protein References for RHAG Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RHAG Gene

Domains & Families for RHAG Gene

Gene Families for RHAG Gene

HGNC:
IUPHAR :
Human Protein Atlas (HPA):
  • CD markers
  • Disease related genes
  • Potential drug targets
  • Predicted membrane proteins
  • Transporters

Protein Domains for RHAG Gene

Blocks:
  • Rhesus blood group protein signature
  • Rh-like protein/ammonium transporter
InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for RHAG Gene

GenScript: Design optimal peptide antigens:
  • Rh50 protein (Q16416_HUMAN)
  • Rh50 protein (Q16417_HUMAN)
  • Rh-associated glycoprotein (Q96E98_HUMAN)
  • Rh50 glycoprotein (Q9UBB8_HUMAN)
  • Rh-associated glycoprotein, isoform CRA_c (Q9UHG9_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q02094

UniProtKB/Swiss-Prot:

RHAG_HUMAN :
  • Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
Family:
  • Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
genes like me logo Genes that share domains with RHAG: view

Function for RHAG Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Molecular function for RHAG Gene

UniProtKB/Swiss-Prot Function:
Associated with rhesus blood group antigen expression (PubMed:19744193). May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane (PubMed:11062476, PubMed:11861637). Involved in ammonia transport across the erythrocyte membrane (PubMed:21849667, PubMed:22012326). Seems to act in monovalent cation transport (PubMed:18931342, PubMed:21849667).
GENATLAS Biochemistry:
glycoprotein RH50,component of the RH antigen multisubunit complex,required for transport and assembly of the Rh membrane complex to the red blood cell surface

Phenotypes From GWAS Catalog for RHAG Gene

Gene Ontology (GO) - Molecular Function for RHAG Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008519 ammonium transmembrane transporter activity IEA,TAS --
GO:0022840 leak channel activity IDA 18931342
GO:0030506 ankyrin binding IPI 12719424
GO:0035379 carbon dioxide transmembrane transporter activity TAS --
genes like me logo Genes that share ontologies with RHAG: view
genes like me logo Genes that share phenotypes with RHAG: view

Human Phenotype Ontology for RHAG Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for RHAG Gene

MGI Knock Outs for RHAG:

Animal Model Products

CRISPR Products

miRNA for RHAG Gene

miRTarBase miRNAs that target RHAG

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RHAG

Clone Products

  • Addgene plasmids for RHAG

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for RHAG Gene

Localization for RHAG Gene

Subcellular locations from UniProtKB/Swiss-Prot for RHAG Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for RHAG gene
Compartment Confidence
plasma membrane 5
extracellular 2
cytoskeleton 2
mitochondrion 2
nucleus 2
endoplasmic reticulum 2
cytosol 2
peroxisome 1
endosome 1
lysosome 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Endoplasmic reticulum (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for RHAG Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005623 cell IEA --
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane IBA,TAS 21873635
GO:0016020 membrane IDA,IEA 22012326
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with RHAG: view

Pathways & Interactions for RHAG Gene

genes like me logo Genes that share pathways with RHAG: view

Gene Ontology (GO) - Biological Process for RHAG Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006873 cellular ion homeostasis IDA 15856280
GO:0015670 carbon dioxide transport IDA 16574458
GO:0015672 monovalent inorganic cation transport IDA 18931342
GO:0015696 ammonium transport IGI,IEA 11062476
GO:0015701 bicarbonate transport TAS --
genes like me logo Genes that share ontologies with RHAG: view

No data available for SIGNOR curated interactions for RHAG Gene

Drugs & Compounds for RHAG Gene

Products:

  1. Drug

(5) Drugs for RHAG Gene - From: DGIdb, IUPHAR, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Ammonia Approved Pharma 0
[<sup>14</sup>C]methylamine Pharma 0

(5) Additional Compounds for RHAG Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with RHAG: view

Transcripts for RHAG Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for RHAG Gene

1 REFSEQ mRNAs :
14 NCBI additional mRNA sequence :
8 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RHAG

Clone Products

  • Addgene plasmids for RHAG

Alternative Splicing Database (ASD) splice patterns (SP) for RHAG Gene

No ASD Table

Relevant External Links for RHAG Gene

GeneLoc Exon Structure for
RHAG

Expression for RHAG Gene

Products:

  1. Primer
  2. Gene Expression Assay

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for RHAG Gene

mRNA expression in normal human tissues for RHAG Gene
mRNA expression by GTEx for RHAG GenemRNA expression by BioGPS for RHAG Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for RHAG Gene

This gene is overexpressed in Whole Blood (x22.0) and Heart - Atrial Appendage (x4.6).

Protein differential expression in normal tissues from HIPED for RHAG Gene

This gene is overexpressed in Ovary (11.4), Placenta (10.0), Skin (9.5), and Platelet (7.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for RHAG Gene



Transcriptomic regulation report from SPP (The Signaling Pathways Project) for RHAG

SOURCE GeneReport for Unigene cluster for RHAG Gene:

Hs.120950

mRNA Expression by UniProt/SwissProt for RHAG Gene:

Q02094-RHAG_HUMAN
Tissue specificity: Erythrocytes.

Evidence on tissue expression from TISSUES for RHAG Gene

  • Bone marrow(4.4)
  • Liver(4.4)
  • Heart(4.3)
  • Blood(3.3)

Phenotype-based relationships between genes and organs from Gene ORGANizer for RHAG Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
Systems:
  • cardiovascular
  • digestive
  • integumentary
  • nervous
  • skeletal muscle
Regions:
Head and neck:
  • ear
  • eye
  • head
  • mouth
Abdomen:
  • liver
General:
  • blood
  • red blood cell
  • skin
genes like me logo Genes that share expression patterns with RHAG: view

No data available for Protein tissue co-expression partners for RHAG Gene

Orthologs for RHAG Gene

This gene was present in the common ancestor of animals.

Orthologs for RHAG Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
 Mammalia RHAG 31 30
  • 99.27 (n)
 OneToOne
dog
(Canis familiaris)
 Mammalia RHAG 31 30
  • 82.23 (n)
 OneToOne
mouse
(Mus musculus)
 Mammalia Rhag 17 31 30
  • 80.28 (n)
cow
(Bos Taurus)
 Mammalia RHAG 31 30
  • 80.28 (n)
 OneToOne
rat
(Rattus norvegicus)
 Mammalia Rhag 30
  • 79.63 (n)
oppossum
(Monodelphis domestica)
 Mammalia RHAG 31
  • 72 (a)
 OneToOne
platypus
(Ornithorhynchus anatinus)
 Mammalia RHAG 31
  • 62 (a)
 OneToOne
chicken
(Gallus gallus)
 Aves RHAG 31 30
  • 72.12 (n)
 OneToOne
lizard
(Anolis carolinensis)
 Reptilia RHAG 31
  • 58 (a)
 OneToOne
tropical clawed frog
(Silurana tropicalis)
 Amphibia LOC100495681 30
  • 67.99 (n)
African clawed frog
(Xenopus laevis)
 Amphibia Rh50 30
zebrafish
(Danio rerio)
 Actinopterygii rhag 31 30
  • 66.67 (n)
 OneToOne
rainbow trout
(Oncorhynchus mykiss)
 Actinopterygii Omy.3979 30
fruit fly
(Drosophila melanogaster)
 Insecta Rh50 31 32
  • 40 (a)
 OneToMany
worm
(Caenorhabditis elegans)
 Secernentea rhr-1 31 32 30
  • 53.06 (n)
 ManyToMany
rhr-2 31 32
  • 37 (a)
 ManyToMany
sea squirt
(Ciona savignyi)
 Ascidiacea CSA.7848 31
  • 45 (a)
 ManyToMany
CSA.7075 31
  • 44 (a)
 ManyToMany
-- 31
  • 43 (a)
 ManyToMany
Species where no ortholog for RHAG was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for RHAG Gene

ENSEMBL:
Gene Tree for RHAG (if available)
TreeFam:
Gene Tree for RHAG (if available)
Aminode:
Evolutionary constrained regions (ECRs) for RHAG: view image

Paralogs for RHAG Gene

Paralogs for RHAG Gene

(11) SIMAP similar genes for RHAG Gene using alignment to 7 proteins:

  • RHAG_HUMAN
  • M1SZX7_HUMAN
  • M5FJR4_HUMAN
  • Q96E98_HUMAN
  • Q9UBB8_HUMAN
  • Q9UHG9_HUMAN
  • Q9UK69_HUMAN
genes like me logo Genes that share paralogs with RHAG: view

Variants for RHAG Gene

Products:

  1. SNP Genotyping and Copy Number Assay

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for RHAG Gene

SNP ID Clinical significance and condition Chr 06 pos Variation AA Info Type
741788 Likely Benign: not provided 49,611,101(-) G/A SYNONYMOUS_VARIANT
792184 Likely Benign: not provided 49,611,016(-) T/C INTRON_VARIANT
rs104893987 Regulator type Rh-null hemolytic anemia (RHN) [MIM:268150] p.Gly280Arg
rs121918586 Pathogenic: Rh-mod syndrome. Regulator type Rh-null hemolytic anemia (RHN) [MIM:268150] 49,619,284(-) C/Tp.Ser79Asn MISSENSE_VARIANT
rs121918587 Pathogenic: Rh-null, regulator type. Regulator type Rh-null hemolytic anemia (RHN) [MIM:268150] 49,612,506(-) C/Tp.Gly279Glu MISSENSE_VARIANT

Additional dbSNP identifiers (rs#s) for RHAG Gene

Structural Variations from Database of Genomic Variants (DGV) for RHAG Gene

Variant ID Type Subtype PubMed ID
dgv5960n100 CNV gain 25217958

Variation tolerance for RHAG Gene

Residual Variation Intolerance Score: 52.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.39; 71.12% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for RHAG Gene

Blood Group Antigen Gene Mutation Database (BGMUT)
Blood Group System
Human Gene Mutation Database (HGMD)
RHAG
SNPedia medical, phenotypic, and genealogical associations of SNPs for
RHAG

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RHAG Gene

Disorders for RHAG Gene

MalaCards: The human disease database

(13) MalaCards diseases for RHAG Gene - From: UniProtKB/Swiss-Prot, OMIM, ClinVar, GTR, Orphanet, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
overhydrated hereditary stomatocytosis
  • ohst
rh-null, regulator type
  • rhnr
retinohepatoendocrinologic syndrome
  • rhe syndrome
hereditary stomatocytosis
  • hereditary stomatocytic disease
hemolytic anemia
  • anemia hemolytic
- elite association - COSMIC cancer census association via MalaCards
Search RHAG in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

RHAG_HUMAN
  • Regulator type Rh-null hemolytic anemia (RHN) [MIM:268150]: Form of chronic hemolytic anemia in which the red blood cells have a stomatocytosis and spherocytosis morphology, an increased osmotic fragility, an altered ion transport system, and abnormal membrane phospholipid organization. {ECO:0000269 PubMed:10467273, ECO:0000269 PubMed:8563755, ECO:0000269 PubMed:9454778, ECO:0000269 PubMed:9716608}. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Overhydrated hereditary stomatocytosis (OHST) [MIM:185000]: An autosomal dominant disorder of red cell membrane permeability to monovalent cations, characterized by macrocytic hemolytic anemia of fluctuating severity, circulating erythrocytes with slit-like lucencies (stomata) evident on fixed, stained peripheral blood smears. OHST red cells exhibit cation leak, resulting in elevated cell sodium content with reduced potassium content. The disease is marked by splenomegaly or hepatosplenomegaly, cholelithiasis and a strong tendency for iron overload. {ECO:0000269 PubMed:18931342, ECO:0000269 PubMed:21849667, ECO:0000269 PubMed:22012326}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Additional Disease Information for RHAG

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with RHAG: view

No data available for Genatlas for RHAG Gene

Publications for RHAG Gene

  1. Human RhAG ammonia channel is impaired by the Phe65Ser mutation in overhydrated stomatocytic red cells. (PMID: 22012326) Genetet S … Mouro-Chanteloup I (American journal of physiology. Cell physiology 2012) 2 3 4 54
  2. The monovalent cation leak in overhydrated stomatocytic red blood cells results from amino acid substitutions in the Rh-associated glycoprotein. (PMID: 18931342) Bruce LJ … Stewart GW (Blood 2009) 3 4 23 54
  3. Exclusion of the juvenile myoclonic epilepsy gene EFHC1 as the cause of migraine on chromosome 6, but association to two rare polymorphisms in MEP1A and RHAG. (PMID: 16378686) Norberg A … Holmberg M (Neuroscience letters 2006) 3 23 41 54
  4. Mechanism of genetic complementation of ammonium transport in yeast by human erythrocyte Rh-associated glycoprotein. (PMID: 14966114) Westhoff CM … Foskett JK (The Journal of biological chemistry 2004) 3 4 23 54
  5. The human Rhesus-associated RhAG protein and a kidney homologue promote ammonium transport in yeast. (PMID: 11062476) Marini AM … Chérif-Zahar B (Nature genetics 2000) 3 4 23 54

ExternalLinks

View latest publications for RHAG gene in Mastermind

Products for RHAG Gene

  • Addgene plasmids for RHAG

Sources for RHAG Gene