Free for academic non-profit institutions. Other users need a Commercial license
RGSL1 (Regulator Of G Protein Signaling Like 1) is a Protein Coding gene. Among its related pathways are RET signaling and Signaling by GPCR. An important paralog of this gene is AXIN2.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0016020 | membrane | IEA | -- |
GO:0016021 | integral component of membrane | IEA | -- |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Signaling by GPCR | ||
2 | RET signaling | ||
3 | Peptide ligand-binding receptors | ||
4 | ADP signalling through P2Y purinoceptor 12 |
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | RGSL1 30 |
|
||
Dog (Canis familiaris) |
Mammalia | RGSL1 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | RGSL1 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Rgsl1 30 17 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
-- 31 |
|
OneToMany | |||
Oppossum (Monodelphis domestica) |
Mammalia | RGSL1 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | LOC100858077 30 |
|
||
RGSL1 31 |
|
OneToOne | |||
Lizard (Anolis carolinensis) |
Reptilia | RGSL1 31 |
|
OneToOne | |
Zebrafish (Danio rerio) |
Actinopterygii | LOC565777 30 |
|
SNP ID | Clinical significance and condition | Chr 01 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
743373 | Likely Benign: not provided | 182,556,042(+) | C/T | SYNONYMOUS_VARIANT | |
rs12083859 | - | p.Glu5Asp | |||
rs647224 | - | p.Trp256Cys |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv3302826 | CNV | tandem duplication | 20981092 |
esv3302856 | CNV | tandem duplication | 20981092 |
esv3404570 | CNV | insertion | 20981092 |
nsv1068350 | CNV | deletion | 25765185 |
nsv1140429 | CNV | tandem duplication | 24896259 |
nsv528762 | CNV | loss | 19592680 |
nsv548358 | CNV | gain | 21841781 |
nsv825531 | CNV | loss | 20364138 |
nsv825542 | CNV | gain | 20364138 |
nsv825553 | CNV | gain | 20364138 |
No disorders were found for RGSL1 Gene.