Aliases for RGS9 Gene
External Ids for RGS9 Gene
Previous GeneCards Identifiers for RGS9 Gene
This gene encodes a member of the RGS family of GTPase activating proteins that function in various signaling pathways by accelerating the deactivation of G proteins. This protein is anchored to photoreceptor membranes in retinal cells and deactivates G proteins in the rod and cone phototransduction cascades. Mutations in this gene result in bradyopsia. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
GeneCards Summary for RGS9 Gene
RGS9 (Regulator Of G Protein Signaling 9) is a Protein Coding gene. Diseases associated with RGS9 include Prolonged Electroretinal Response Suppression and Leber Plus Disease. Among its related pathways are Signaling by GPCR and Metabolism of fat-soluble vitamins. Gene Ontology (GO) annotations related to this gene include obsolete signal transducer activity. An important paralog of this gene is RGS11.
UniProtKB/Swiss-Prot Summary for RGS9 Gene
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to GNAT1. Involved in phototransduction; key element in the recovery phase of visual transduction (By similarity).