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This gene is a member of the regulator of G protein signaling (RGS) family and encodes a protein with a single RGS domain. Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. They accelerate transit through the cycle of GTP binding and hydrolysis to GDP, thereby terminating signal transduction, but pa... See more...
Aliases for RGS8 Gene
Aliases for RGS8 Gene
External Ids for RGS8 Gene
- HGNC: 16810
- Entrez Gene: 85397
- Ensembl: ENSG00000135824
- OMIM: 607189
- UniProtKB: P57771
Previous GeneCards Identifiers for RGS8 Gene
- GC01M180141
- GC01M178044
- GC01M179131
- GC01M179855
- GC01M179347
- GC01M180877
- GC01M153852
Summaries for RGS8 Gene
-
This gene is a member of the regulator of G protein signaling (RGS) family and encodes a protein with a single RGS domain. Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. They accelerate transit through the cycle of GTP binding and hydrolysis to GDP, thereby terminating signal transduction, but paradoxically, also accelerate receptor-stimulated activation. [provided by RefSeq, Jul 2008]
GeneCards Summary for RGS8 Gene
RGS8 (Regulator Of G Protein Signaling 8) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors. Gene Ontology (GO) annotations related to this gene include GTPase activator activity. An important paralog of this gene is RGS16.
UniProtKB/Swiss-Prot Summary for RGS8 Gene
-
Regulates G protein-coupled receptor signaling cascades, including signaling via muscarinic acetylcholine receptor CHRM2 and dopamine receptor DRD2 (By similarity). Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:18434541). Modulates the activity of potassium channels that are activated in response to DRD2 and CHRM2 signaling (By similarity).
Additional gene information for RGS8 Gene
- HGNC(16810)
- Entrez Gene(85397)
- Ensembl(ENSG00000135824)
- OMIM(607189)
- UniProtKB(P57771)
- Open Targets Platform(ENSG00000135824)
- Monarch Initiative
- Search for RGS8 at DataMed
- Search for RGS8 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for RGS8 Gene
Genomics for RGS8 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for RGS8 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH01J182671 | Promoter/Enhancer | 1.1 | EPDnew Ensembl CraniofacialAtlas | 600.2 | +81.4 | 81392 | 0.6 | ZIC2 ZNF341 GLIS1 SMARCA4 GATA2 | RGS8 RGS16 lnc-RGS8-1 lnc-RGS8-6 | |
| GH01J182753 | Promoter/Enhancer | 0.7 | EPDnew Ensembl ENCODE | 600.7 | +0.7 | 692 | 1.6 | RGS8 RGS16 LINC01688 piR-39488-029 | ||
| GH01J182672 | Promoter | 0.5 | EPDnew | 600.2 | +80.4 | 80416 | 0.1 | PRDM1 ZNF600 | RGS8 RGS16 lnc-RGS8-1 lnc-RGS8-6 | |
| GH01J182755 | Enhancer | 0.2 | Ensembl | 600.7 | -1.2 | -1208 | 0.6 | RGS8 LINC01688 NPL | ||
| GH01J182632 | Enhancer | 1.2 | Ensembl ENCODE dbSUPER | 11.2 | +119.7 | 119692 | 3.6 | CREB1 PRDM10 ZNF629 ZNF692 TARDBP FOXA1 ZIC2 PATZ1 NR2C1 IKZF2 | RGS16 RGS8 lnc-RGS8-6 LINC01686 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around RGS8 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for RGS8
- Top Transcription factor binding sites by QIAGEN in the RGS8 gene promoter:
-
- c-Myb
- Lmo2
- NF-AT
- NF-AT1
- NF-AT2
- NF-AT3
- NF-AT4
- PPAR-gamma1
- PPAR-gamma2
- TBP
Genomic Locations for RGS8 Gene
Genomic Locations for RGS8 Gene
- chr1:182,641,814-182,753,293
- (GRCh38/hg38)
- Size:
- 111,480 bases
- Orientation:
- Minus strand
- chr1:182,615,239-182,653,711
- (GRCh37/hg19)
- Size:
- 38,473 bases
- Orientation:
- Minus strand
Genomic View for RGS8 Gene
Genes around RGS8 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1q25.3 by HGNC
- 1q25.3 by Entrez Gene
- 1q25.3 by Ensembl
RGS8 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for RGS8 Gene
Proteins for RGS8 Gene
-
Protein details for RGS8 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P57771-RGS8_HUMAN
- Recommended name:
- Regulator of G-protein signaling 8
- Protein Accession:
- P57771
- B4DGL9
- Q3SYD2
Protein attributes for RGS8 Gene
- Size:
- 180 amino acids
- Molecular mass:
- 20917 Da
- Quaternary structure:
-
- Interacts with GNAO1 (By similarity). Interacts with GNAI3.
Protein Expression for RGS8 Gene
Post-translational modifications for RGS8 Gene
Other Protein References for RGS8 Gene
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for RGS8
- Novus Biologicals Antibodies for RGS8
-
Abcam antibodies for RGS8
- Invitrogen Antibodies for RGS8 (AFLGC-RGS8)
-
Santa Cruz Biotechnology (SCBT) Antibodies for RGS8
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for RGS8
- Origene Custom Protein Services for RGS8
-
Abcam proteins for RGS8
No data available for DME Specific Peptides for RGS8 Gene
Domains & Families for RGS8 Gene
Gene Families for RGS8 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for RGS8 Gene
Suggested Antigen Peptide Sequences for RGS8 Gene
- GenScript: Design optimal peptide antigens:
-
- Regulator of G-protein signaling 8 (RGS8_HUMAN)
No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for RGS8 Gene
Function for RGS8 Gene
Molecular function for RGS8 Gene
- UniProtKB/Swiss-Prot Function:
- Regulates G protein-coupled receptor signaling cascades, including signaling via muscarinic acetylcholine receptor CHRM2 and dopamine receptor DRD2 (By similarity). Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:18434541). Modulates the activity of potassium channels that are activated in response to DRD2 and CHRM2 signaling (By similarity).
Phenotypes From GWAS Catalog for RGS8 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003924 | GTPase activity | TAS | -- |
| GO:0005096 | GTPase activator activity | IEA,IDA | 18434541 |
| GO:0005515 | protein binding | IPI | 25416956 |
Phenotypes for RGS8 Gene
- MGI mutant phenotypes for RGS8:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for RGS8:
Animal Models for RGS8 Gene
- MGI Knock Outs for RGS8:
-
- Rgs8 Rgs8<tm1.1Atai>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for RGS8 - Select products 50% OFF >
- * RGS8 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for RGS8
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RGS8
-
Santa Cruz Biotechnology (SCBT) CRISPR for RGS8
miRNA for RGS8 Gene
- miRTarBase miRNAs that target RGS8
-
- mmu-miR-541-5p (MIRT008136)
- mmu-miR-425-5p (MIRT008501)
- mmu-miR-7b-5p (MIRT009213)
- mmu-miR-30e-5p (MIRT013318)
- hsa-miR-335-5p (MIRT018211)
- mmu-miR-150-5p (MIRT054908)
- mmu-miR-297c-5p (MIRT581327)
- mmu-miR-297a-5p (MIRT581328)
- mmu-miR-297b-5p (MIRT581329)
- mmu-miR-511-3p (MIRT581330)
- mmu-miR-1198-5p (MIRT581331)
- mmu-miR-466p-5p (MIRT581332)
- mmu-miR-466e-5p (MIRT581333)
- mmu-miR-1187 (MIRT581334)
- mmu-miR-466a-5p (MIRT581335)
- mmu-miR-878-5p (MIRT596364)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for RGS8
- Browse OriGene Inhibitory RNA Products For RGS8
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RGS8
Clone Products
- Applied Biological Materials (abm): Clones for RGS8 - Select products 50% OFF >
- * RGS8 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for RGS8
- Addgene plasmids for RGS8
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RGS8
Cell Line Products
-
Horizon Cell Lines for RGS8
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for RGS8 Gene
Localization for RGS8 Gene
Subcellular locations from UniProtKB/Swiss-Prot for RGS8 Gene
- Cell membrane. Peripheral membrane protein. Cytoplasmic side. Membrane. Peripheral membrane protein. Cytoplasmic side. Perikaryon. Cell projection, dendrite. Nucleus. Note=Detected in Purkinje cell soma and dendrites. Associated with Purkinje cell membranes. Not detected in Purkinje cell nuclei. Detected in the nucleus after heterologous expression. Recruited to the cell membrane in the presence of GNAO1. {ECO:0000250 UniProtKB:P49804}.
| Compartment | Confidence |
|---|---|
| plasma membrane | 4 |
| nucleus | 4 |
| cytosol | 3 |
| extracellular | 2 |
| cytoskeleton | 1 |
| endoplasmic reticulum | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | ISS | -- |
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0030425 | dendrite | ISS | -- |
| GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane | ISS | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for RGS8 Gene
Pathways & Interactions for RGS8 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Signaling by GPCR | ||
| 2 | G-AlphaQ Signaling |
G-AlphaI Signaling
.47
|
G-AlphaQ Signaling
.47
|
| 3 | MAPK Erk Pathway | ||
| 4 | Activation of cAMP-Dependent PKA |
cAMP Pathway
.77
|
|
| 5 | Peptide ligand-binding receptors | ||
Pathways by source for RGS8 Gene
1 Sino Biological pathway for RGS8 Gene
4 Reactome pathways for RGS8 Gene
3 Qiagen pathways for RGS8 Gene
- cAMP Pathway
- G-AlphaI Signaling
- G-AlphaQ Signaling
Interacting Proteins for RGS8 Gene
Selected Interacting proteins:
P57771-RGS8_HUMAN
ENSP00000258302
for RGS8 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for RGS8
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007186 | G protein-coupled receptor signaling pathway | IEA,TAS | -- |
| GO:0007213 | G protein-coupled acetylcholine receptor signaling pathway | ISS | -- |
| GO:0009968 | negative regulation of signal transduction | IEA | -- |
| GO:0043547 | positive regulation of GTPase activity | IEA,IDA | 18434541 |
| GO:0060159 | regulation of dopamine receptor signaling pathway | ISS | -- |
No data available for SIGNOR curated interactions for RGS8 Gene
Transcripts for RGS8 Gene
mRNA/cDNA for RGS8 Gene
- 3 REFSEQ mRNAs :
- 16 NCBI additional mRNA sequence :
- 7 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000258302 5606 nts (view in UCSC)
- ENST00000367556 843 nts (view in UCSC)
- ENST00000367557 859 nts (view in UCSC)
- ENST00000483095 1432 nts (view in UCSC)
- ENST00000491420 781 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for RGS8 - Select products 50% OFF >
- * RGS8 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for RGS8
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RGS8
-
Santa Cruz Biotechnology (SCBT) CRISPR for RGS8
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for RGS8
- Browse OriGene Inhibitory RNA Products For RGS8
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RGS8
Clone Products
- Applied Biological Materials (abm): Clones for RGS8 - Select products 50% OFF >
- * RGS8 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for RGS8
- Addgene plasmids for RGS8
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RGS8
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||||||
| SP2: | - |
Relevant External Links for RGS8 Gene
- GeneLoc Exon Structure for
- RGS8
Expression for RGS8 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
- Neural Tube (Nervous System)
-
Skeletal Muscle (Muscoskeletal System)
- Mononuclear Myocytes Hyoid Arch Muscles
- Mononuclear Myocytes Mandibular Arch Muscles
- Epiblast (Early Embryonic Tissues)
- NULL (Uncategorized)
-
Spinal Cord (Nervous System)
mRNA differential expression in normal tissues according to GTEx for RGS8 Gene
This gene is overexpressed in Brain - Nucleus accumbens (basal ganglia) (x14.1), Brain - Caudate (basal ganglia) (x6.9), and Brain - Putamen (basal ganglia) (x6.6).
This gene is overexpressed in Monocytes (41.2), Retina (16.9), and Adipocyte (10.9).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for RGS8 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for RGS8
SOURCE GeneReport for Unigene cluster for RGS8 Gene:
Hs.20982Evidence on tissue expression from TISSUES for RGS8 Gene
- Nervous system(4.4)
Primer Products
-
OriGene qPCR primer pairs for RGS8
-
OriGene qPCR primer pairs and template standards for RGS8
Gene Expression Assay Products
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for RGS8 Gene
Orthologs for RGS8 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | RGS8 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | RGS8 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | RGS8 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Rgs8 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Rgs8 30 17 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | RGS8 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | RGS8 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | RGS8 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | RGS8 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | rgs8 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | rgs8 30 31 |
|
OneToOne | |
| Rainbow Trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.6075 30 |
|
- Species where no ortholog for RGS8 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for RGS8 Gene
- ENSEMBL:
- Gene Tree for RGS8 (if available)
- TreeFam:
- Gene Tree for RGS8 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for RGS8: view image
Paralogs for RGS8 Gene
Paralogs for RGS8 Gene
(20) SIMAP similar genes for RGS8 Gene using alignment to 2 proteins:
- RGS8_HUMAN
- D6RD36_HUMAN
Variants for RGS8 Gene
Residual Variation Intolerance Score:
38.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
5.88;
74.18% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for RGS8 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- RGS8
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for RGS8 Gene
Disorders for RGS8 Gene
Additional Disease Information for RGS8
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No disorders were found for RGS8 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RGS8 Gene
Publications for RGS8 Gene
- Cloning and characterization of 13 novel transcripts and the human RGS8 gene from the 1q25 region encompassing the hereditary prostate cancer (HPC1) locus. (PMID: 11318611) Sood R … Carpten JD (Genomics 2001) 2 3 4 23
- Association of RGS2 and RGS5 variants with schizophrenia symptom severity. (PMID: 18262772) Campbell DB … Sullivan PF (Schizophrenia research 2008) 3 23 41
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 41
- Genetic variations in regulator of G-protein signaling genes as susceptibility loci for second primary tumor/recurrence in head and neck squamous cell carcinoma. (PMID: 20627871) Wang J … Wu X (Carcinogenesis 2010) 3 41
- Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits. (PMID: 18434541) Soundararajan M … Siderovski DP (Proceedings of the National Academy of Sciences of the United States of America 2008) 3 4
ExternalLinks
Products for RGS8 Gene
- Custom Antibody ServicesOriGene Antibodies for RGS8
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for MassSpec and Protein Over-expression Lysates for RGS8
- Origene Custom Protein Services for RGS8
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- Browse OriGene Inhibitory RNA Products For RGS8
- OriGene qPCR primer pairs for RGS8
- OriGene qPCR primer pairs and template standards for RGS8
- OriGene CRISPR knockouts for RGS8
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For RGS8
- Sino Biological Human cDNA Clone for RGS8
- Browse Sino Biological Recombinant Proteins
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- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for RGS8
- Novus Biologicals proteins and lysates for RGS8
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for RGS8
- Abcam proteins for RGS8
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for RGS8 (AFLGC-RGS8)
- VectorBuilder Custom and pre-made DNA vectors for RGS8 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for RGS8 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for RGS8 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for RGS8 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for RGS8
- Addgene plasmids for RGS8
- antibodies-online: Show 16 available RGS8 Antibodies ranked by validation data
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- antibodies-online: Search results for available RGS8 related products ranked by validation data
- antibodies-online: Show 8 available RGS8 Proteins ranked by validation data
- Compare Top RGS8 Proteins
- Santa Cruz Biotechnology (SCBT) Antibodies for RGS8
- Search Santa Cruz Biotechnology (SCBT) for RGS8 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for RGS8
- Horizon Cell Lines for RGS8
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RGS8
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RGS8
- Search GeneCopoeia for miRNA 3'UTR Target clone products for RGS8
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RGS8
Sources for RGS8 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
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