Aliases for RGS16 Gene
External Ids for RGS16 Gene
Previous GeneCards Identifiers for RGS16 Gene
The protein encoded by this gene belongs to the 'regulator of G protein signaling' family. It inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits. It also may play a role in regulating the kinetics of signaling in the phototransduction cascade. [provided by RefSeq, Jul 2008]
GeneCards Summary for RGS16 Gene
RGS16 (Regulator Of G Protein Signaling 16) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Myometrial Relaxation and Contraction Pathways. Gene Ontology (GO) annotations related to this gene include GTPase activator activity and calmodulin binding. An important paralog of this gene is RGS8.
UniProtKB/Swiss-Prot Summary for RGS16 Gene
Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:11602604, PubMed:18434541). Plays an important role in the phototransduction cascade by regulating the lifetime and effective concentration of activated transducin alpha. May regulate extra and intracellular mitogenic signals (By similarity).