Aliases for RGS11 Gene
External Ids for RGS11 Gene
Previous GeneCards Identifiers for RGS11 Gene
The protein encoded by this gene belongs to the RGS (regulator of G protein signaling) family. Members of the RGS family act as GTPase-activating proteins on the alpha subunits of heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2013]
GeneCards Summary for RGS11 Gene
RGS11 (Regulator Of G Protein Signaling 11) is a Protein Coding gene. Diseases associated with RGS11 include Prolonged Electroretinal Response Suppression and Bullous Retinoschisis. Among its related pathways are Signaling by GPCR and Myometrial Relaxation and Contraction Pathways. Gene Ontology (GO) annotations related to this gene include obsolete signal transducer activity and G-protein beta-subunit binding. An important paralog of this gene is RGS9.
UniProtKB/Swiss-Prot Summary for RGS11 Gene
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.