Aliases for RGP1 Gene
External Ids for RGP1 Gene
Previous HGNC Symbols for RGP1 Gene
Previous GeneCards Identifiers for RGP1 Gene
GeneCards Summary for RGP1 Gene
RGP1 (RGP1 Homolog, RAB6A GEF Complex Partner 1) is a Protein Coding gene. Among its related pathways are Retrograde transport at the Trans-Golgi-Network and Vesicle-mediated transport. Gene Ontology (GO) annotations related to this gene include Rab GTPase binding and Rab guanyl-nucleotide exchange factor activity.
UniProtKB/Swiss-Prot Summary for RGP1 Gene
The RIC1-RGP1 complex acts as a guanine nucleotide exchange factor (GEF), which activates RAB6A by exchanging bound GDP for free GTP and may thereby required for efficient fusion of endosome-derived vesicles with the Golgi compartment. The RIC1-RGP1 complex participates in the recycling of mannose-6-phosphate receptors.