Aliases for RGMB Gene
External Ids for RGMB Gene
Previous GeneCards Identifiers for RGMB Gene
RGMB is a glycosylphosphatidylinositol (GPI)-anchored member of the repulsive guidance molecule family (see RGMA, MIM 607362) and contributes to the patterning of the developing nervous system (Samad et al., 2005 [PubMed 15671031]).[supplied by OMIM, Apr 2009]
GeneCards Summary for RGMB Gene
RGMB (Repulsive Guidance Molecule BMP Co-Receptor B) is a Protein Coding gene. Diseases associated with RGMB include Spinal Polio and Dermatomycosis. Among its related pathways are Netrin-1 signaling and Signaling by BMP. Gene Ontology (GO) annotations related to this gene include identical protein binding and coreceptor activity. An important paralog of this gene is RGMA.
UniProtKB/Swiss-Prot Summary for RGMB Gene
Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system (By similarity). Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling (By similarity). Promotes neuronal adhesion (By similarity). May inhibit neurite outgrowth.