Aliases for RGMB Gene
External Ids for RGMB Gene
Previous GeneCards Identifiers for RGMB Gene
RGMB is a glycosylphosphatidylinositol (GPI)-anchored member of the repulsive guidance molecule family (see RGMA, MIM 607362) and contributes to the patterning of the developing nervous system (Samad et al., 2005 [PubMed 15671031]).[supplied by OMIM, Apr 2009]
GeneCards Summary for RGMB Gene
RGMB (Repulsive Guidance Molecule BMP Co-Receptor B) is a Protein Coding gene. Diseases associated with RGMB include Hemochromatosis Type 2. Among its related pathways are TGF-beta signaling pathway (KEGG) and Developmental Biology. Gene Ontology (GO) annotations related to this gene include identical protein binding and coreceptor activity. An important paralog of this gene is RGMA.
UniProtKB/Swiss-Prot Summary for RGMB Gene
Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system (By similarity). Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling (By similarity). Promotes neuronal adhesion (By similarity). May inhibit neurite outgrowth.