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RGL3 (Ral Guanine Nucleotide Dissociation Stimulator Like 3) is a Protein Coding gene. Among its related pathways are Cytoskeleton remodeling_RalB regulation pathway. Gene Ontology (GO) annotations related to this gene include guanyl-nucleotide exchange factor activity and Ral guanyl-nucleotide exchange factor activity. An important paralog of this gene is ENSG00000285245.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005085 | guanyl-nucleotide exchange factor activity | IEA | -- |
GO:0008321 | Ral guanyl-nucleotide exchange factor activity | IEA | -- |
GO:0017016 | Ras GTPase binding | IEA | -- |
GO:0031267 | small GTPase binding | IEA | -- |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Cytoskeleton remodeling_RalB regulation pathway |
Cytoskeleton remodeling_RalB regulation pathway
-
|
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0007165 | signal transduction | IEA | -- |
GO:0007264 | small GTPase mediated signal transduction | IEA | -- |
GO:0043547 | positive regulation of GTPase activity | IEA | -- |
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | RGL3 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | RGL3 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | RGL3 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Rgl3 30 17 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Rgl3 30 |
|
||
Oppossum (Monodelphis domestica) |
Mammalia | RGL3 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | RGL3 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | RGL3 31 |
|
OneToOne | |
Zebrafish (Danio rerio) |
Actinopterygii | rgl3a 31 |
|
OneToMany | |
RGL3 (1 of 2) 31 |
|
OneToMany | |||
Fruit Fly (Drosophila melanogaster) |
Insecta | Rgl 31 |
|
OneToMany | |
Worm (Caenorhabditis elegans) |
Secernentea | rgl-1 31 |
|
OneToMany | |
Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv1464086 | CNV | deletion | 17803354 |
esv2673946 | CNV | deletion | 23128226 |
esv3556030 | CNV | deletion | 23714750 |
esv3643671 | CNV | loss | 21293372 |
esv3643672 | CNV | loss | 21293372 |
nsv519802 | CNV | loss | 19592680 |
nsv833752 | CNV | loss | 17160897 |
nsv953975 | CNV | deletion | 24416366 |
No disorders were found for RGL3 Gene.