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Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated ankyrin-containing protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates th... See more...
Aliases for RFXAP Gene
Aliases for RFXAP Gene
External Ids for RFXAP Gene
- HGNC: 9988
- Entrez Gene: 5994
- Ensembl: ENSG00000133111
- OMIM: 601861
- UniProtKB: O00287
Previous GeneCards Identifiers for RFXAP Gene
- GC13P035379
- GC13P031379
- GC13P036329
- GC13P035191
- GC13P036291
- GC13P037393
- GC13P018207
Summaries for RFXAP Gene
-
Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated ankyrin-containing protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group D. Transcript variants utilizing different polyA signals have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for RFXAP Gene
RFXAP (Regulatory Factor X Associated Protein) is a Protein Coding gene. Diseases associated with RFXAP include Bare Lymphocyte Syndrome, Type Ii and Severe Combined Immunodeficiency. Among its related pathways are Tuberculosis and Primary immunodeficiency. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and transcription coactivator activity.
UniProtKB/Swiss-Prot Summary for RFXAP Gene
-
Part of the RFX complex that binds to the X-box of MHC II promoters.
Additional gene information for RFXAP Gene
- HGNC(9988)
- Entrez Gene(5994)
- Ensembl(ENSG00000133111)
- OMIM(601861)
- UniProtKB(O00287)
- Open Targets Platform(ENSG00000133111)
- Monarch Initiative
- Search for RFXAP at DataMed
- Search for RFXAP at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for RFXAP Gene
Genomics for RFXAP Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for RFXAP Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around RFXAP on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for RFXAP
- Top Transcription factor binding sites by QIAGEN in the RFXAP gene promoter:
-
- E47
- FOXO1
- FOXO1a
- HNF-1
- HNF-1A
- ISGF-3
- MyoD
- Nkx6-1
- Tal-1beta
- USF1
Genomic Locations for RFXAP Gene
Genomic Locations for RFXAP Gene
- chr13:36,819,222-36,829,104
- (GRCh38/hg38)
- Size:
- 9,883 bases
- Orientation:
- Plus strand
- chr13:37,393,339-37,403,740
- (GRCh37/hg19)
- Size:
- 10,402 bases
- Orientation:
- Plus strand
Genomic View for RFXAP Gene
Genes around RFXAP on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 13q13.3 by HGNC
- 13q13.3 by Entrez Gene
- 13q13.3 by Ensembl
RFXAP Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for RFXAP Gene
Proteins for RFXAP Gene
-
Protein details for RFXAP Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O00287-RFXAP_HUMAN
- Recommended name:
- Regulatory factor X-associated protein
- Protein Accession:
- O00287
- B2R9T8
- Q5VZM6
- Q8TC40
Protein attributes for RFXAP Gene
- Size:
- 272 amino acids
- Molecular mass:
- 28232 Da
- Quaternary structure:
-
- The RFX heterotetrameric complex consists of 2 molecules of RFX5 and one each of RFXAP and RFX-B/RFXANK; with each subunit representing a separate complementation group. RFX forms cooperative DNA binding complexes with X2BP and CBF/NF-Y. RFX associates with CIITA to form an active transcriptional complex.
Protein Expression for RFXAP Gene
Post-translational modifications for RFXAP Gene
- Phosphorylated.
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for RFXAP Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Creative Diagnostics Anti-RFXAP (full length) polyclonal antibody
- Creative Biolabs Recombinant Anti-Human RFXAP Antibody and Mouse Anti-RFXAP Recombinant Antibody (1B5)
- Novus Biologicals Antibodies for RFXAP
-
Abcam antibodies for RFXAP
- Invitrogen Antibodies for RFXAP (AFLGC-RFXAP)
-
Santa Cruz Biotechnology (SCBT) Antibodies for RFXAP
Protein Products
-
OriGene Purified Proteins for RFXAP
- Search Origene for MassSpec and Protein Over-expression Lysates for RFXAP
- Origene Custom Protein Services for RFXAP
- antibodies-online: Show 4 available RFXAP Proteins ranked by validation data
- Compare Top RFXAP Proteins
-
Quality Products:
-
Abcam proteins for RFXAP
Assay Products
- antibodies-online: Show 4 available RFXAP Elisa Kits ranked by validation data
- Compare Top RFXAP Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for RFXAP Gene
Domains & Families for RFXAP Gene
Gene Families for RFXAP Gene
- Human Protein Atlas (HPA):
-
- Disease related genes
- Predicted intracellular proteins
- Transcription factors
Protein Domains for RFXAP Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for RFXAP Gene
- GenScript: Design optimal peptide antigens:
-
- RFX DNA-binding complex 36 kDa subunit (RFXAP_HUMAN)
Graphical View of Domain Structure for InterPro Entry
O00287UniProtKB/Swiss-Prot:
RFXAP_HUMAN :- The C-terminal domain is necessary for the RFX complex formation.
- Domain:
-
- The C-terminal domain is necessary for the RFX complex formation.
Function for RFXAP Gene
Molecular function for RFXAP Gene
- UniProtKB/Swiss-Prot Function:
- Part of the RFX complex that binds to the X-box of MHC II promoters.
- GENATLAS Biochemistry:
- transactivating DNA binding regulatory factor,component AP,36kDa,involved in MHC class II expression,subunit of the RFX complex,interacting with RFX5
Phenotypes From GWAS Catalog for RFXAP Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000976 | contributes_to transcription regulatory region sequence-specific DNA binding | IDA | 9806546 |
| GO:0003677 | DNA binding | TAS,IBA | 21873635 |
| GO:0003700 | DNA-binding transcription factor activity | NAS | -- |
| GO:0003713 | transcription coactivator activity | TAS,IDA | 9118943 |
Phenotypes for RFXAP Gene
- GenomeRNAi human phenotypes for RFXAP:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for RFXAP - Select products 50% OFF >
- * RFXAP CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
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-
OriGene CRISPR knockouts for RFXAP
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RFXAP
-
Santa Cruz Biotechnology (SCBT) CRISPR for RFXAP
miRNA for RFXAP Gene
- miRTarBase miRNAs that target RFXAP
-
- mmu-miR-190a-5p (MIRT013583)
- hsa-miR-218-5p (MIRT439775)
- hsa-miR-520h (MIRT711773)
- hsa-miR-520g-3p (MIRT711774)
- hsa-miR-454-3p (MIRT711775)
- hsa-miR-4295 (MIRT711776)
- hsa-miR-3666 (MIRT711777)
- hsa-miR-301b-3p (MIRT711778)
- hsa-miR-301a-3p (MIRT711779)
- hsa-miR-130b-3p (MIRT711780)
- hsa-miR-130a-3p (MIRT711781)
- hsa-miR-519c-3p (MIRT711782)
- hsa-miR-519b-3p (MIRT711783)
- hsa-miR-519a-3p (MIRT711784)
- hsa-miR-93-5p (MIRT711785)
- hsa-miR-526b-3p (MIRT711786)
- hsa-miR-519d-3p (MIRT711787)
- hsa-miR-20b-5p (MIRT711788)
- hsa-miR-20a-5p (MIRT711789)
- hsa-miR-17-5p (MIRT711790)
- hsa-miR-106b-5p (MIRT711791)
- hsa-miR-106a-5p (MIRT711792)
- hsa-miR-212-3p (MIRT732549)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for RFXAP
- Browse OriGene Inhibitory RNA Products For RFXAP
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RFXAP
Clone Products
- Applied Biological Materials (abm): Clones for RFXAP - Select products 50% OFF >
- * RFXAP as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for RFXAP
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RFXAP
Cell Line Products
-
Horizon Cell Lines for RFXAP
No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for RFXAP Gene
Localization for RFXAP Gene
Subcellular locations from UniProtKB/Swiss-Prot for RFXAP Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 2 |
| plasma membrane | 1 |
| extracellular | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| lysosome | 1 |
- Nuclear speckles (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IBA | 21873635 |
| GO:0005667 | transcription factor complex | IPI | 9806546 |
| GO:0016607 | nuclear speck | IDA | -- |
Pathways & Interactions for RFXAP Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Allograft rejection | ||
| 2 | Primary immunodeficiency | ||
| 3 | Tuberculosis | ||
Pathways by source for RFXAP Gene
3 KEGG pathways for RFXAP Gene
Interacting Proteins for RFXAP Gene
GPS-Prot Interaction Network for RFXAP
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0045893 | positive regulation of transcription, DNA-templated | IBA | 21873635 |
| GO:0045944 | positive regulation of transcription by RNA polymerase II | IDA, IMP | 9118943 |
No data available for SIGNOR curated interactions for RFXAP Gene
Transcripts for RFXAP Gene
mRNA/cDNA for RFXAP Gene
- 1 REFSEQ mRNAs :
- 3 NCBI additional mRNA sequence :
- 2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000255476 2306 nts (view in UCSC)
- ENST00000472888 534 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for RFXAP - Select products 50% OFF >
- * RFXAP CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for RFXAP
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RFXAP
-
Santa Cruz Biotechnology (SCBT) CRISPR for RFXAP
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for RFXAP
- Browse OriGene Inhibitory RNA Products For RFXAP
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RFXAP
Clone Products
- Applied Biological Materials (abm): Clones for RFXAP - Select products 50% OFF >
- * RFXAP as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for RFXAP
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RFXAP
Relevant External Links for RFXAP Gene
- GeneLoc Exon Structure for
- RFXAP
Expression for RFXAP Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Liver (Hepatobiliary System)
This gene is overexpressed in Blymphocyte (23.3), Peripheral blood mononuclear cells (8.8), CD8 Tcells (7.8), and Thyroid (7.1).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for RFXAP Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for RFXAP
SOURCE GeneReport for Unigene cluster for RFXAP Gene:
Hs.24422mRNA Expression by UniProt/SwissProt for RFXAP Gene:
O00287-RFXAP_HUMAN
Tissue specificity:
Ubiquitous.
Evidence on tissue expression from TISSUES for RFXAP Gene
- Blood(4.5)
- Nervous system(4.3)
- Lymph node(2.1)
Phenotype-based relationships between genes and organs from Gene ORGANizer for RFXAP Gene
Germ Layers:
- ectoderm
- endoderm
- mesoderm
Systems:
- digestive
- immune
- integumentary
- nervous
- respiratory
- urinary
Regions:
Head and neck:
- brain
- head
- larynx
- meninges
- neck
- pharynx
Thorax:
- bronchus
- lung
- trachea
Abdomen:
- biliary tract
- gallbladder
- intestine
- kidney
- large intestine
- liver
- pancreas
- small intestine
Pelvis:
- ureter
- urethra
- urinary bladder
Limb:
- digit
- finger
- foot
- hand
- lower limb
- nail
- toe
- upper limb
General:
- blood
- skin
- white blood cell
Primer Products
-
OriGene qPCR primer pairs for RFXAP
-
OriGene qPCR primer pairs and template standards for RFXAP
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues for RFXAP Gene
Orthologs for RFXAP Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | RFXAP 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | RFXAP 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | RFXAP 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Rfxap 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Rfxap 30 17 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | RFXAP 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | RFXAP 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | RFXAP 31 |
|
OneToOne | |
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.30365 30 |
|
||
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | Str.20047 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | rfxap 31 |
|
OneToOne | |
| Dr.12444 30 |
|
- Species where no ortholog for RFXAP was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for RFXAP Gene
- ENSEMBL:
- Gene Tree for RFXAP (if available)
- TreeFam:
- Gene Tree for RFXAP (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for RFXAP: view image
Paralogs for RFXAP Gene
No data available for Paralogs for RFXAP Gene
Variants for RFXAP Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for RFXAP Gene
| SNP ID | Clinical significance and condition | Chr 13 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 636400 | Uncertain Significance: not provided | 36,819,716(+) | G/A | MISSENSE_VARIANT | |
| 636582 | Uncertain Significance: not provided | 36,819,591(+) | C/A | SYNONYMOUS_VARIANT | |
| 643242 | Uncertain Significance: Bare lymphocyte syndrome 2 | 36,819,371(+) | G/T | MISSENSE_VARIANT | |
| 644661 | Uncertain Significance: Bare lymphocyte syndrome 2 | 36,819,486(+) | A/G | SYNONYMOUS_VARIANT | |
| 645743 | Uncertain Significance: Bare lymphocyte syndrome 2 | 36,819,593(+) | G/A | MISSENSE_VARIANT |
Gene Damage Index Score:
0.98;
20.24% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for RFXAP Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RFXAP Gene
Disorders for RFXAP Gene
(7) MalaCards diseases for RFXAP Gene - From: OMIM, ClinVar, GTR, Orphanet, DISEASES, Novoseek, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| bare lymphocyte syndrome, type ii |
|
|
| severe combined immunodeficiency |
|
|
| retinitis pigmentosa 48 |
|
|
| immune deficiency disease |
|
|
| bare lymphocyte syndrome, type i |
|
|
Search RFXAP in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
RFXAP_HUMAN- Bare lymphocyte syndrome 2 (BLS2) [MIM:209920]: A severe combined immunodeficiency disease with early onset. It is characterized by a profound defect in constitutive and interferon-gamma induced MHC II expression, absence of cellular and humoral T-cell response to antigen challenge, hypogammaglobulinemia and impaired antibody production. The consequence include extreme susceptibility to viral, bacterial and fungal infections. {ECO:0000269 PubMed:10072068, ECO:0000269 PubMed:9118943}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Additional Disease Information for RFXAP
- Genetic Association Database
- (GAD)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for Genatlas for RFXAP Gene
Publications for RFXAP Gene
- RFXAP, a novel subunit of the RFX DNA binding complex is mutated in MHC class II deficiency. (PMID: 9118943) Durand B … Reith W (The EMBO journal 1997) 2 3 4 23
- Coordinate loss of MHC class II expression in the diffuse large B cell lymphoma cell line OCI-Ly2 is due to a novel mutation in RFX-AP. (PMID: 20024540) Bushway M … Murphy SP (Immunogenetics 2010) 3 23
- Solution structure of the heterotrimeric complex between the interaction domains of RFX5 and RFXAP from the RFX gene regulatory complex. (PMID: 20732328) Laird KM … Garvie CW (Journal of molecular biology 2010) 3 4
- Formation of the RFX gene regulatory complex induces folding of the interaction domain of RFXAP. (PMID: 19274739) Briggs L … Garvie CW (Proteins 2009) 3 23
- Transcriptional silencing of RFXAP in MHC class II-deficiency. (PMID: 18336911) van Eggermond MC … van den Elsen PJ (Molecular immunology 2008) 3 23
ExternalLinks
Products for RFXAP Gene
- Custom Antibody Services
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- OriGene qPCR primer pairs for RFXAP
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- Sino Biological Human cDNA Clone for RFXAP
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- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for RFXAP
- Novus Biologicals proteins and lysates for RFXAP
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for RFXAP
- Abcam proteins for RFXAP
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for RFXAP (AFLGC-RFXAP)
- VectorBuilder Custom and pre-made DNA vectors for RFXAP (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for RFXAP (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for RFXAP (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for RFXAP CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for RFXAP
- antibodies-online: Show 18 available RFXAP Antibodies ranked by validation data
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- antibodies-online: Show 4 available RFXAP Elisa Kits ranked by validation data
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- Quality Products:
- antibodies-online: Show 4 available RFXAP Proteins ranked by validation data
- Compare Top RFXAP Proteins
- Quality Products:
- Santa Cruz Biotechnology (SCBT) Antibodies for RFXAP
- Search Santa Cruz Biotechnology (SCBT) for RFXAP siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for RFXAP
- Horizon Cell Lines for RFXAP
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RFXAP
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RFXAP
- Search GeneCopoeia for miRNA 3'UTR Target clone products for RFXAP
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RFXAP
Sources for RFXAP Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
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