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Aliases for RFPL1S Gene

Subcategory (RNA class) for RFPL1S Gene

non-coding RNA

Quality Score for this RNA gene is

13

Aliases for RFPL1S Gene

  • RFPL1 Antisense RNA 1 2 3 5
  • RFPL1 Antisense RNA 1 (Non-Protein Coding) 2 3
  • Non-Protein Coding RNA 6 2 3
  • NCRNA00006 3
  • RFPL1-AS1 3
  • RFPL1-AS 3
  • RFPL1AS 3

External Ids for RFPL1S Gene

Previous HGNC Symbols for RFPL1S Gene

  • RFPL1-AS1

Previous GeneCards Identifiers for RFPL1S Gene

  • GC22U990065
  • GC22M028163
  • GC22M029833

Summaries for RFPL1S Gene

GeneCards Summary for RFPL1S Gene

RFPL1S (RFPL1 Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class.

Additional gene information for RFPL1S Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RFPL1S Gene

Genomics for RFPL1S Gene

GeneHancer (GH) Regulatory Elements for RFPL1S Gene

Promoters and enhancers for RFPL1S Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH22J029419 Promoter/Enhancer 1.3 EPDnew Ensembl ENCODE 18.5 +57.1 57074 5 IKZF1 IKZF2 SOX6 CTBP1 NR2F1 ZFHX2 TCF12 ZEB2 EGR2 CBFA2T3 AP1B1 RFPL1S GAS2L1 NEFH THOC5 ENSG00000272858 ENSG00000242156 LOC102723305
GH22J029456 Enhancer 0.6 Ensembl ENCODE 10.4 +21.7 21658 1 RFX1 BMI1 ZNF335 RFPL1S PIR46787 RFPL1
GH22J029470 Enhancer 0.9 ENCODE 6.3 +7.6 7584 1.1 SP1 CTCF ZSCAN21 SP7 KLF14 CREM CREB1 GLIS2 GMEB1 ZBTB8A RFPL1 THOC5 RFPL1S NIPSNAP1 PIR46787
GH22J029443 Enhancer 0.5 Ensembl 10.8 +34.4 34374 0.8 PRDM10 ZNF341 ZNF366 ZBTB40 ZFP37 RFPL1S THOC5 MTFP1 RFPL1 PIR46787
GH22J029431 Enhancer 0.4 Ensembl ENCODE 11.5 +45.8 45840 1.3 RFPL4AP6 RFPL1S NIPSNAP1 ENSG00000242156
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around RFPL1S on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the RFPL1S gene promoter:
  • E47
  • En-1
  • GCNF
  • GCNF-1
  • GCNF-2
  • Hand1
  • RFX1
  • ZID

Genomic Locations for RFPL1S Gene

Genomic Locations for RFPL1S Gene
chr22:29,436,534-29,478,175
(GRCh38/hg38)
Size:
41,642 bases
Orientation:
Minus strand
chr22:29,832,818-29,874,164
(GRCh37/hg19)
Size:
41,347 bases
Orientation:
Minus strand

Genomic View for RFPL1S Gene

Genes around RFPL1S on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RFPL1S Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RFPL1S Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RFPL1S Gene

Proteins for RFPL1S Gene

Post-translational modifications for RFPL1S Gene

No Post-translational modifications

No data available for DME Specific Peptides for RFPL1S Gene

Domains & Families for RFPL1S Gene

Suggested Antigen Peptide Sequences for RFPL1S Gene

GenScript: Design optimal peptide antigens:
  • RFPL1 antisense RNA 1 (RFL1S_HUMAN)

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains and UniProtKB/Swiss-Prot for RFPL1S Gene

Function for RFPL1S Gene

Molecular function for RFPL1S Gene

GENATLAS Biochemistry:
ret finger protein-like 1,antisense transcript,overlapping RFRL1

Phenotypes From GWAS Catalog for RFPL1S Gene

genes like me logo Genes that share phenotypes with RFPL1S: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RFPL1S Gene

Localization for RFPL1S Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for RFPL1S Gene

Pathways & Interactions for RFPL1S Gene

PathCards logo

SuperPathways for RFPL1S Gene

No Data Available

Interacting Proteins for RFPL1S Gene

Gene Ontology (GO) - Biological Process for RFPL1S Gene

None

No data available for Pathways by source and SIGNOR curated interactions for RFPL1S Gene

Drugs & Compounds for RFPL1S Gene

No Compound Related Data Available

Transcripts for RFPL1S Gene

mRNA/cDNA for RFPL1S Gene

(5) Additional mRNA sequences :
(3) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(3) RNA Central transcripts :

Unigene Clusters for RFPL1S Gene

RFPL1 antisense RNA 1:
Representative Sequences:

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for RFPL1S Gene

No ASD Table

Relevant External Links for RFPL1S Gene

GeneLoc Exon Structure for
RFPL1S
ECgene alternative splicing isoforms for
RFPL1S

Expression for RFPL1S Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for RFPL1S Gene

mRNA differential expression in normal tissues according to GTEx for RFPL1S Gene

This gene is overexpressed in Brain - Frontal Cortex (BA9) (x8.0), Brain - Anterior cingulate cortex (BA24) (x6.4), Brain - Cortex (x6.3), Brain - Hippocampus (x4.5), Brain - Amygdala (x4.4), Brain - Putamen (basal ganglia) (x4.1), and Brain - Nucleus accumbens (basal ganglia) (x4.0).

NURSA nuclear receptor signaling pathways regulating expression of RFPL1S Gene:

RFPL1S

SOURCE GeneReport for Unigene cluster for RFPL1S Gene:

Hs.167750
genes like me logo Genes that share expression patterns with RFPL1S: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RFPL1S Gene

Orthologs for RFPL1S Gene

Evolution for RFPL1S Gene

ENSEMBL:
Gene Tree for RFPL1S (if available)
TreeFam:
Gene Tree for RFPL1S (if available)

No data available for Orthologs for RFPL1S Gene

Paralogs for RFPL1S Gene

No data available for Paralogs for RFPL1S Gene

Variants for RFPL1S Gene

Sequence variations from dbSNP and Humsavar for RFPL1S Gene

SNP ID Clin Chr 22 pos Variation AA Info Type
rs1000744123 -- 29,439,404(-) C/G non_coding_transcript_variant
rs1001921686 -- 29,438,771(-) T/G non_coding_transcript_variant
rs1003019815 -- 29,436,942(-) G/A downstream_transcript_variant
rs1003484459 -- 29,443,492(-) G/T upstream_transcript_variant
rs1004263945 -- 29,442,816(-) TT/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for RFPL1S Gene

Variant ID Type Subtype PubMed ID
nsv1059994 CNV gain 25217958
nsv1060197 CNV gain 25217958
nsv1110864 OTHER inversion 24896259
nsv964618 CNV duplication 23825009
nsv979667 CNV duplication 23825009

Additional Variant Information for RFPL1S Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
RFPL1S

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for RFPL1S Gene

Disorders for RFPL1S Gene

Additional Disease Information for RFPL1S

No disorders were found for RFPL1S Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RFPL1S Gene

Publications for RFPL1S Gene

  1. Duplications on human chromosome 22 reveal a novel Ret Finger Protein-like gene family with sense and endogenous antisense transcripts. (PMID: 10508838) Seroussi E … Dumanski JP (Genome research 1999) 2 3 23 58
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 58
  3. A genome annotation-driven approach to cloning the human ORFeome. (PMID: 15461802) Collins JE … Dunham I (Genome biology 2004) 3 58
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for RFPL1S Gene

Sources for RFPL1S Gene

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