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Aliases for RFPL1S Gene
Subcategory (RNA class) for RFPL1S Gene
lncRNA
Number of RNA Genes sources:
3 / 17
Aliases for RFPL1S Gene
External Ids for RFPL1S Gene
- HGNC: 9978
- Entrez Gene: 10740
- Ensembl: ENSG00000225465
- OMIM: 605972
Previous HGNC Symbols for RFPL1S Gene
- RFPL1-AS1
Previous GeneCards Identifiers for RFPL1S Gene
- GC22U990065
- GC22M028163
- GC22M029833
Summaries for RFPL1S Gene
GeneCards Summary for RFPL1S Gene
RFPL1S (RFPL1 Antisense RNA 1) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with RFPL1S include Astrocytoma and Retinitis Pigmentosa 6.
Additional gene information for RFPL1S Gene
- HGNC(9978)
- Entrez Gene(10740)
- Ensembl(ENSG00000225465)
- OMIM(605972)
- Open Targets Platform(ENSG00000225465)
- Search for RFPL1S at DataMed
- Search for RFPL1S at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for RFPL1S Gene
Genomics for RFPL1S Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for RFPL1S Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH22J029478 | Promoter/Enhancer | 1.1 | EPDnew Ensembl | 600.7 | +0.5 | 467 | 1.6 | PRDM10 REST EZH2 ZNF600 SP2 ZNF766 NFE2 ZNF316 ZBTB48 AFF1 | NEFH LOC107985541 RFPL1S NIPSNAP1 THOC5 piR-52788 AP1B1 L13304-023 | |
| GH22J029441 | Promoter | 0.3 | EPDnew | 600.3 | +37.2 | 37205 | 0.1 | RFPL1S FJ601684-298 RFPL4AP6 AP1B1 NEFH RFPL1 L13304-023 | ||
| GH22J029477 | Enhancer | 0.2 | Ensembl | 600.7 | +1.6 | 1567 | 0.2 | RFPL1S LOC107985541 NEFH piR-52788 AP1B1 L13304-023 | ||
| GH22J029419 | Enhancer | 0.8 | Ensembl ENCODE | 18.5 | +59.2 | 59167 | 1.8 | IKZF2 SOX6 CTBP1 ZFHX2 IKZF1 NR2F1 SPI1 NR2F6 TCF12 ZEB2 | RFPL1S GAS2L1 ENSG00000272858 AP1B1 ENSG00000242156 piR-43979-001 RFPL1 L13304-023 | |
| GH22J029423 | Promoter/Enhancer | 0.6 | EPDnew Ensembl | 12.6 | +55.6 | 55567 | 0.6 | CBFA2T3 | AP1B1 ENSG00000242156 RFPL1 RFPL1S THOC5 RFPL4AP6 NEFH L13304-023 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around RFPL1S on the GeneHancer Hub at the UCSC Golden Path
- Top Transcription factor binding sites by QIAGEN in the RFPL1S gene promoter:
-
- E47
- En-1
- GCNF
- GCNF-1
- GCNF-2
- Hand1
- RFX1
- ZID
Genomic Locations for RFPL1S Gene
Genomic Locations for RFPL1S Gene
- chr22:29,436,534-29,478,868
- (GRCh38/hg38)
- Size:
- 42,335 bases
- Orientation:
- Minus strand
- chr22:29,832,818-29,874,164
- (GRCh37/hg19)
- Size:
- 41,347 bases
- Orientation:
- Minus strand
Genomic View for RFPL1S Gene
Genes around RFPL1S on UCSC Golden Path with GeneCards custom track
RFPL1S in the GeneCards ncRNA compendium hub on the UCSC Golden Path
- Cytogenetic band:
-
- 22q12.2 by HGNC
- 22q12.2 by Entrez Gene
- 22q12.2 by Ensembl
RFPL1S Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for RFPL1S Gene
Proteins for RFPL1S Gene
Post-translational modifications for RFPL1S Gene
No Post-translational modifications
Antibody Products
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for RFPL1S
- Origene Custom Protein Services for RFPL1S
No data available for DME Specific Peptides for RFPL1S Gene
Domains & Families for RFPL1S Gene
Gene Families for RFPL1S Gene
Suggested Antigen Peptide Sequences for RFPL1S Gene
- GenScript: Design optimal peptide antigens:
-
- RFPL1 antisense RNA 1 (RFL1S_HUMAN)
No data available for Protein Domains , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for RFPL1S Gene
Function for RFPL1S Gene
Molecular function for RFPL1S Gene
- GENATLAS Biochemistry:
- ret finger protein-like 1,antisense transcript,overlapping RFRL1
Phenotypes From GWAS Catalog for RFPL1S Gene
Phenotypes for RFPL1S Gene
- GenomeRNAi human phenotypes for RFPL1S:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for RFPL1S - Select products 50% OFF >
- * RFPL1S CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Browse CRISPR knockouts for RFPL1S
miRNA Products
Inhibitory RNA Products
Clone Products
- Applied Biological Materials (abm): Clones for RFPL1S - Select products 50% OFF >
- * RFPL1S as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RFPL1S Gene
Localization for RFPL1S Gene
| Compartment | Confidence |
|---|---|
| peroxisome | 1 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for RFPL1S Gene
Transcripts for RFPL1S Gene
Non-coding RNA (ncRNA) Transcripts from RNAcentral for RFPL1S Gene
| RNAcentral Transcript ID | Subcategory | Length (nts) | # of Sources | Source Identifiers and Annotations |
|---|---|---|---|---|
| URS00005FCF98_9606 | lncRNA | 570 | 3 |
Ensembl: ENST00000419368 (view in UCSC) , LNCipedia: RFPL1S:6, NONCODE: NONHSAT084709.2, |
| URS0000811B84_9606 | lncRNA | 5903 | 2 |
Ensembl: ENST00000461286 (view in UCSC) , LNCipedia: RFPL1S:3, |
| URS000075AF51_9606 | lncRNA | 5115 | 2 |
HGNC: 9978, RefSeq: NR_002727, |
| URS0000EF1643_9606 | lncRNA | 1931 | 1 |
Ensembl: ENST00000657516 (view in UCSC) , |
| URS0000EEC3FA_9606 | lncRNA | 1636 | 1 |
Ensembl: ENST00000661328 (view in UCSC) , |
RFPL1S in the GeneCards ncRNA compendium hub on the UCSC Golden Path
Additional transcripts not in RNAcentral for RFPL1S Gene
- 5 NCBI additional mRNA sequence :
- 1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000539579 330 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for RFPL1S - Select products 50% OFF >
- * RFPL1S CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Browse CRISPR knockouts for RFPL1S
miRNA Products
Inhibitory RNA Products
Clone Products
- Applied Biological Materials (abm): Clones for RFPL1S - Select products 50% OFF >
- * RFPL1S as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
Relevant External Links for RFPL1S Gene
- GeneLoc Exon Structure for
- RFPL1S
Expression for RFPL1S Gene
mRNA differential expression in normal tissues according to GTEx for RFPL1S Gene
This gene is overexpressed in Brain - Frontal Cortex (BA9) (x8.0), Brain - Anterior cingulate cortex (BA24) (x6.4), Brain - Cortex (x6.3), Brain - Hippocampus (x4.5), Brain - Amygdala (x4.4), Brain - Putamen (basal ganglia) (x4.1), and Brain - Nucleus accumbens (basal ganglia) (x4.0).
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for RFPL1S
SOURCE GeneReport for Unigene cluster for RFPL1S Gene:
Hs.167750Primer Products
-
OriGene qPCR primer pairs for RFPL1S
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RFPL1S Gene
Orthologs for RFPL1S Gene
No data available for Orthologs for RFPL1S Gene
Paralogs for RFPL1S Gene
No data available for Paralogs for RFPL1S Gene
Variants for RFPL1S Gene
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv1059994 | CNV | gain | 25217958 |
| nsv1060197 | CNV | gain | 25217958 |
| nsv1110864 | OTHER | inversion | 24896259 |
| nsv964618 | CNV | duplication | 23825009 |
| nsv979667 | CNV | duplication | 23825009 |
Additional Variant Information for RFPL1S Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- RFPL1S
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for RFPL1S Gene
Disorders for RFPL1S Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| astrocytoma |
|
|
| retinitis pigmentosa 6 |
|
|
Search RFPL1S in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for RFPL1S
No data available for UniProtKB/Swiss-Prot and Genatlas for RFPL1S Gene
Publications for RFPL1S Gene
- Duplications on human chromosome 22 reveal a novel Ret Finger Protein-like gene family with sense and endogenous antisense transcripts. (PMID: 10508838) Seroussi E … Dumanski JP (Genome research 1999) 2 3 23
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3
- A genome annotation-driven approach to cloning the human ORFeome. (PMID: 15461802) Collins JE … Dunham I (Genome biology 2004) 3
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3
ExternalLinks
Products for RFPL1S Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for RFPL1S
- Origene Custom Protein Services for RFPL1S
- Browse OriGene Inhibitory RNA Products For RFPL1S
- OriGene qPCR primer pairs for RFPL1S
- Browse CRISPR knockouts for RFPL1S
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For RFPL1S
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- antibodies-online: Search results for available RFPL1-AS1 related products ranked by validation data
- antibodies-online: Search results for available RFPL1-AS1 related products ranked by validation data
- antibodies-online: Search results for available RFPL1-AS1 related products ranked by validation data
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for knockout CRISPR/Cas9 clones, lentivirus, and/or AAV products for RFPL1S
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles, and/or promoter clone products for RFPL1S
- Search GeneCopoeia for miRNA 3'UTR Target clone products for RFPL1S
- Search GeneCopoeia for shRNA, lentivirus, and/or AAV clone products for RFPL1S
Sources for RFPL1S Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB