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RFPL1 (Ret Finger Protein Like 1) is a Protein Coding gene. An important paralog of this gene is RFPL3.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0004842 | ubiquitin-protein transferase activity | IBA | 21873635 |
GO:0005515 | protein binding | IEA | -- |
GO:0046872 | metal ion binding | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000785 | chromatin | IBA | 21873635 |
GO:0005634 | nucleus | IEA | -- |
GO:0005654 | nucleoplasm | IBA | 21873635 |
GO:0005737 | cytoplasm | IEA,IDA | 20725088 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0007049 | cell cycle | IEA | -- |
GO:0008285 | negative regulation of cell proliferation | IDA | 20725088 |
GO:0010972 | negative regulation of G2/M transition of mitotic cell cycle | IDA | 20725088 |
GO:0016567 | protein ubiquitination | IEA | -- |
GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | IMP | 20725088 |
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | RFPL3 30 |
|
||
RFPL1 31 |
|
OneToOne | |||
Dog (Canis familiaris) |
Mammalia | -- 31 |
|
OneToMany | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
ManyToMany | |
Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
ManyToMany |
SNP ID | Clinical significance and condition | Chr 22 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs16987627 | - | p.Trp94Arg | |||
rs3804076 | - | p.Met127Thr |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
nsv1059994 | CNV | gain | 25217958 |
nsv1060197 | CNV | gain | 25217958 |
nsv1110864 | OTHER | inversion | 24896259 |
nsv964618 | CNV | duplication | 23825009 |
nsv979667 | CNV | duplication | 23825009 |
No disorders were found for RFPL1 Gene.