Aliases for REXO2 Gene
External Ids for REXO2 Gene
Previous GeneCards Identifiers for REXO2 Gene
This gene encodes a 3'-to-5' exonuclease specific for small (primarily 5 nucleotides or less in length) single-stranded RNA and DNA oligomers. This protein may have a role in DNA repair, replication, and recombination, and in RNA processing and degradation. It may also be involved in resistance of human cells to UV-C-induced cell death through its role in the DNA repair process. [provided by RefSeq, Nov 2011]
GeneCards Summary for REXO2 Gene
REXO2 (RNA Exonuclease 2) is a Protein Coding gene. Diseases associated with REXO2 include Immunodeficiency 13 and Noonan Syndrome 1. Among its related pathways are Ribosome biogenesis in eukaryotes. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and 3'-5'-exoribonuclease activity.
UniProtKB/Swiss-Prot Summary for REXO2 Gene
3'-to-5' exoribonuclease specific for small oligoribonucleotides. Active on small (primarily </=5 nucleotides in length) single-stranded RNA and DNA oligomers. May have a role in cellular nucleotide recycling.