Aliases for REXO2 Gene
External Ids for REXO2 Gene
Previous GeneCards Identifiers for REXO2 Gene
This gene encodes a 3'-to-5' exonuclease specific for small (primarily 5 nucleotides or less in length) single-stranded RNA and DNA oligomers. This protein may have a role in DNA repair, replication, and recombination, and in RNA processing and degradation. It may also be involved in resistance of human cells to UV-C-induced cell death through its role in the DNA repair process. [provided by RefSeq, Nov 2011]
GeneCards Summary for REXO2 Gene
REXO2 (RNA Exonuclease 2) is a Protein Coding gene. Diseases associated with REXO2 include Lennox-Gastaut Syndrome and Noonan Syndrome 1. Among its related pathways are Ribosome biogenesis in eukaryotes. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and 3'-5'-exoribonuclease activity.
UniProtKB/Swiss-Prot Summary for REXO2 Gene
3'-to-5' exoribonuclease specific for small oligoribonucleotides. Active on small (primarily </=5 nucleotides in length) single-stranded RNA and DNA oligomers. May have a role in cellular nucleotide recycling.