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Aliases for REXO1L1P Gene

Aliases for REXO1L1P Gene

  • REXO1 Like 1, Pseudogene 2 3 5
  • REX1, RNA Exonuclease 1 Homolog-Like 1, Pseudogene 2 3
  • Antigen GOR Homolog 3 4
  • REXO1L1 3 4
  • GOR 3 4
  • REX1, RNA Exonuclease 1 Homolog (S. Cerevisiae)-Like 1, Pseudogene 2
  • REX1, RNA Exonuclease 1 Homolog (S. Cerevisiae)-Like 1 2
  • RNA Exonuclease 1 Homolog-Like 1 4
  • Exonuclease GOR 3
  • EC 3.1.-.- 4

External Ids for REXO1L1P Gene

Previous HGNC Symbols for REXO1L1P Gene

  • REXO1L1

Previous GeneCards Identifiers for REXO1L1P Gene

  • GC08M086570

Summaries for REXO1L1P Gene

GeneCards Summary for REXO1L1P Gene

REXO1L1P (REXO1 Like 1, Pseudogene) is a Pseudogene. Diseases associated with REXO1L1P include Hepatitis C Virus. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and exonuclease activity.

Additional gene information for REXO1L1P Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for REXO1L1P Gene

Genomics for REXO1L1P Gene

Genomic Locations for REXO1L1P Gene

Genomic Locations for REXO1L1P Gene
7,056 bases
Minus strand

Genomic View for REXO1L1P Gene

Genes around REXO1L1P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
REXO1L1P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for REXO1L1P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for REXO1L1P Gene

No data available for GeneHancer (GH) Regulatory Elements for REXO1L1P Gene

Proteins for REXO1L1P Gene

  • Protein details for REXO1L1P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative exonuclease GOR
    Protein Accession:
    Secondary Accessions:
    • A6NK34
    • O95107

    Protein attributes for REXO1L1P Gene

    675 amino acids
    Molecular mass:
    73855 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAN77012.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Sequence of unknown origin in the N-terminal part.; Evidence={ECO:0000305};

neXtProt entry for REXO1L1P Gene

Post-translational modifications for REXO1L1P Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for REXO1L1P Gene

Domains & Families for REXO1L1P Gene

Suggested Antigen Peptide Sequences for REXO1L1P Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the REXO1/REXO3 family.
  • Belongs to the REXO1/REXO3 family.
genes like me logo Genes that share domains with REXO1L1P: view

No data available for Gene Families for REXO1L1P Gene

Function for REXO1L1P Gene

Enzyme Numbers (IUBMB) for REXO1L1P Gene

Gene Ontology (GO) - Molecular Function for REXO1L1P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0004527 exonuclease activity IEA --
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with REXO1L1P: view

Phenotypes for REXO1L1P Gene

genes like me logo Genes that share phenotypes with REXO1L1P: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for REXO1L1P Gene

Localization for REXO1L1P Gene

Subcellular locations from UniProtKB/Swiss-Prot for REXO1L1P Gene

Cytoplasm. Nucleus.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for REXO1L1P gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for REXO1L1P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with REXO1L1P: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for REXO1L1P Gene

Pathways & Interactions for REXO1L1P Gene

SuperPathways for REXO1L1P Gene

No Data Available

Gene Ontology (GO) - Biological Process for REXO1L1P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0090305 nucleic acid phosphodiester bond hydrolysis IEA --
genes like me logo Genes that share ontologies with REXO1L1P: view

No data available for Pathways by source and SIGNOR curated interactions for REXO1L1P Gene

Drugs & Compounds for REXO1L1P Gene

No Compound Related Data Available

Transcripts for REXO1L1P Gene

mRNA/cDNA for REXO1L1P Gene

(1) REFSEQ mRNAs :
(6) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for REXO1L1P Gene

No ASD Table

Relevant External Links for REXO1L1P Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for REXO1L1P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for REXO1L1P Gene

mRNA differential expression in normal tissues according to GTEx for REXO1L1P Gene

This gene is overexpressed in Brain - Cortex (x12.3).

NURSA nuclear receptor signaling pathways regulating expression of REXO1L1P Gene:


Evidence on tissue expression from TISSUES for REXO1L1P Gene

  • Liver(4)
genes like me logo Genes that share expression patterns with REXO1L1P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for REXO1L1P Gene

Orthologs for REXO1L1P Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for REXO1L1P Gene

Organism Taxonomy Gene Similarity Type Details
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 65 (a)
(Monodelphis domestica)
Mammalia -- 34
  • 24 (a)
(Gallus gallus)
Aves -- 34
  • 25 (a)
(Danio rerio)
Actinopterygii rexo1 34
  • 22 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG12877 34
  • 18 (a)
(Caenorhabditis elegans)
Secernentea Y56A3A.33 34
  • 31 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes RNH70 34
  • 18 (a)
Species where no ortholog for REXO1L1P was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for REXO1L1P Gene

Gene Tree for REXO1L1P (if available)
Gene Tree for REXO1L1P (if available)

Paralogs for REXO1L1P Gene

No data available for Paralogs for REXO1L1P Gene

Variants for REXO1L1P Gene

Sequence variations from dbSNP and Humsavar for REXO1L1P Gene

SNP ID Clin Chr 08 pos Variation AA Info Type
rs112143831 -- 85,662,912(-) G/T non_coding_transcript_variant
rs138877160 -- 85,663,520(-) A/G upstream_transcript_variant
rs139593387 -- 85,661,511(-) G/A/T non_coding_transcript_variant
rs140152315 -- 85,663,030(-) T/C non_coding_transcript_variant
rs141939021 -- 85,662,691(-) G/C non_coding_transcript_variant

Variation tolerance for REXO1L1P Gene

Gene Damage Index Score: 0.24; 5.44% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for REXO1L1P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for REXO1L1P Gene

Disorders for REXO1L1P Gene

MalaCards: The human disease database

(1) MalaCards diseases for REXO1L1P Gene - From: GeneCards

Disorder Aliases PubMed IDs
hepatitis c virus
  • hepatitis c virus, susceptibility to
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for REXO1L1P

genes like me logo Genes that share disorders with REXO1L1P: view

No data available for UniProtKB/Swiss-Prot and Genatlas for REXO1L1P Gene

Publications for REXO1L1P Gene

  1. The GOR gene product cannot cross-react with hepatitis C virus in humans. (PMID: 11472404) Koike R … Miyasaka N (Clinical and experimental immunology 2001) 3 4 58
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 58
  3. Expression analysis of pluripotency factors in the undifferentiated porcine inner cell mass and epiblast during in vitro culture. (PMID: 17680630) Blomberg LA … Talbot NC (Molecular reproduction and development 2008) 22 58
  4. Serum immunoglobulin G antibodies to the GOR autoepitope are present in patients with occult hepatitis C virus (HCV) infection despite lack of HCV-specific antibodies. (PMID: 17699833) Quiroga JA … Carreño V (Clinical and vaccine immunology : CVI 2007) 3 58
  5. DNA sequence and analysis of human chromosome 8. (PMID: 16421571) Nusbaum C … Lander ES (Nature 2006) 4 58

Products for REXO1L1P Gene

Sources for REXO1L1P Gene

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