Aliases for RERG Gene
External Ids for RERG Gene
Previous GeneCards Identifiers for RERG Gene
RERG, a member of the RAS superfamily of GTPases, inhibits cell proliferation and tumor formation (Finlin et al., 2001 [PubMed 11533059]).[supplied by OMIM, Mar 2009]
GeneCards Summary for RERG Gene
RERG (RAS Like Estrogen Regulated Growth Inhibitor) is a Protein Coding gene. Diseases associated with RERG include Breast Cancer. Gene Ontology (GO) annotations related to this gene include GTP binding and GDP binding. An important paralog of this gene is RIT1.
UniProtKB/Swiss-Prot Summary for RERG Gene
Binds GDP/GTP and possesses intrinsic GTPase activity. Has higher affinity for GDP than for GTP. In cell lines overexpression leads to a reduction in the rate of proliferation, colony formation and in tumorigenic potential.