Aliases for REG1A Gene
External Ids for REG1A Gene
Previous HGNC Symbols for REG1A Gene
Previous GeneCards Identifiers for REG1A Gene
This gene is a type I subclass member of the Reg gene family. The Reg gene family is a multigene family grouped into four subclasses, types I, II, III and IV, based on the primary structures of the encoded proteins. This gene encodes a protein that is secreted by the exocrine pancreas. It is associated with islet cell regeneration and diabetogenesis and may be involved in pancreatic lithogenesis. Reg family members REG1B, REGL, PAP and this gene are tandemly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication. [provided by RefSeq, Jul 2008]
GeneCards Summary for REG1A Gene
REG1A (Regenerating Family Member 1 Alpha) is a Protein Coding gene. Diseases associated with REG1A include Pancreatitis and Acinar Cell Carcinoma. Among its related pathways are Type II interferon signaling (IFNG) and Angiopoietin Like Protein 8 Regulatory Pathway. Gene Ontology (GO) annotations related to this gene include carbohydrate binding and growth factor activity. An important paralog of this gene is REG1B.
UniProtKB/Swiss-Prot for REG1A Gene
Might act as an inhibitor of spontaneous calcium carbonate precipitation. May be associated with neuronal sprouting in brain, and with brain and pancreas regeneration.