Aliases for REEP2 Gene
External Ids for REEP2 Gene
Previous HGNC Symbols for REEP2 Gene
Previous GeneCards Identifiers for REEP2 Gene
This gene encodes a member of the receptor expression enhancing protein family. Studies of a related gene in mouse suggest that the encoded protein is found in the cell membrane and enhances the function of sweet taste receptors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
GeneCards Summary for REEP2 Gene
REEP2 (Receptor Accessory Protein 2) is a Protein Coding gene. Diseases associated with REEP2 include Spastic Paraplegia 72, Autosomal Recessive and Hereditary Spastic Paraplegia 72. Among its related pathways are Signaling by GPCR and Olfactory transduction. Gene Ontology (GO) annotations related to this gene include taste receptor binding. An important paralog of this gene is REEP1.
UniProtKB/Swiss-Prot Summary for REEP2 Gene
Required for endoplasmic reticulum (ER) network formation, shaping and remodeling. May enhance the cell surface expression of odorant receptors (By similarity).