Aliases for RECK Gene
Aliases for RECK Gene
- Reversion Inducing Cysteine Rich Protein With Kazal Motifs 2 3 5
- Suppressor Of Tumorigenicity 15 Protein 3 4
- ST15 3 4
- Suppression Of Tumorigenicity 15 (Reversion-Inducing-Cysteine-Rich Protein With Kazal Motifs) 3
- Suppression Of Tumorigenicity 5 (Reversion-Inducing-Cysteine-Rich Protein With Kazal Motifs) 3
- Reversion-Inducing Cysteine-Rich Protein With Kazal Motifs 3
- Membrane-Anchored Glycoprotein (Metastasis And Invasion) 3
- HRECK 4
External Ids for RECK Gene
- HGNC: 11345
- Entrez Gene: 8434
- Ensembl: ENSG00000122707
- OMIM: 605227
- UniProtKB: O95980
Previous HGNC Symbols for RECK Gene
- ST15
Previous GeneCards Identifiers for RECK Gene
- GC09P036349
- GC09P036206
- GC09P036026
- GC09P035990
Summaries for RECK Gene
-
The protein encoded by this gene is a cysteine-rich, extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. In normal cells, this membrane-anchored glycoprotein may serve as a negative regulator for matrix metalloproteinase-9, a key enzyme involved in tumor invasion and metastasis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
GeneCards Summary for RECK Gene
RECK (Reversion Inducing Cysteine Rich Protein With Kazal Motifs) is a Protein Coding gene. Diseases associated with RECK include Ovarian Cancer and Middle Ear Squamous Cell Carcinoma. Among its related pathways are MicroRNAs in cancer and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include serine-type endopeptidase inhibitor activity and peptidase inhibitor activity.
UniProtKB/Swiss-Prot for RECK Gene
-
Negatively regulates matrix metalloproteinase-9 (MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK down-regulation by oncogenic signals may facilitate tumor invasion and metastasis. Appears to also regulate MMP-2 and MT1-MMP, which are involved in cancer progression.
Additional gene information for RECK Gene
- Monarch Initiative
- Search for RECK at DataMed
- Search for RECK at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RECK Gene
Genomics for RECK Gene
GeneHancer (GH) Regulatory Elements for RECK Gene
Promoters and enhancers for RECK Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around RECK on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the RECK gene promoter:
-
- MyoD
- C/EBPalpha
- Tal-1beta
- E47
- Max
- c-Myc
- ITF-2
- FOXO4
- ATF6
Regulatory Element Products
Genomic Locations for RECK Gene
Genomic Locations for RECK Gene
- chr9:36,036,433-36,124,455
- (GRCh38/hg38)
- Size:
- 88,023 bases
- Orientation:
- Plus strand
- chr9:36,036,430-36,124,452
- (GRCh37/hg19)
- Size:
- 88,023 bases
- Orientation:
- Plus strand
Genomic View for RECK Gene
Genes around RECK on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 9p13.3 by Entrez Gene
- 9p13.3 by HGNC
- 9p13.3 by Ensembl
RECK Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for RECK Gene
Proteins for RECK Gene
-
Protein details for RECK Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O95980-RECK_HUMAN
- Recommended name:
- Reversion-inducing cysteine-rich protein with Kazal motifs
- Protein Accession:
- O95980
- B2RNS1
- Q5W0K6
- Q8WX37
Protein attributes for RECK Gene
- Size:
- 971 amino acids
- Molecular mass:
- 106457 Da
- Quaternary structure:
-
- Interacts with MMP-9.
Protein Expression for RECK Gene
Post-translational modifications for RECK Gene
- N-glycosylated.
- Glycosylation at posLast=352352, posLast=297297, posLast=200200, Asn86, and posLast=3939
- Modification sites at PhosphoSitePlus
Other Protein References for RECK Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for RECK (RECK)
-
Custom Antibody ServicesOriGene Antibodies for RECK
- Novus Biologicals Antibodies for RECK
-
Abcam antibodies for RECK
- Invitrogen Antibodies for RECK (AFLGC-RECK)
- GeneTex RECK Antibody for RECK
-
Santa Cruz Biotechnology (SCBT) Antibodies for RECK
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for RECK
- Origene Custom Protein Services for RECK
- antibodies-online: Search results for 4 available RECK Proteins ranked by validation data
- Compare Top RECK Proteins
-
Quality Products:
- Search GeneTex for Proteins for RECK
-
Abcam proteins for RECK
Assay Products
- R&D Systems Proteome Profiler Antibody Arrays and other biochemical assays for RECK (RECK)
- antibodies-online: Search results for 8 available RECK Elisa Kits ranked by validation data
- Compare Top RECK Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for RECK Gene
Domains & Families for RECK Gene
Gene Families for RECK Gene
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted membrane proteins
Protein Domains for RECK Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for RECK Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for RECK Gene
Function for RECK Gene
Molecular function for RECK Gene
- UniProtKB/Swiss-Prot Function:
- Negatively regulates matrix metalloproteinase-9 (MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK down-regulation by oncogenic signals may facilitate tumor invasion and metastasis. Appears to also regulate MMP-2 and MT1-MMP, which are involved in cancer progression.
Phenotypes From GWAS Catalog for RECK Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004866 | endopeptidase inhibitor activity | IDA | 9789069 |
| GO:0004867 | serine-type endopeptidase inhibitor activity | IEA | -- |
| GO:0005515 | protein binding | IPI | 21255571 |
| GO:0008191 | metalloendopeptidase inhibitor activity | TAS | 9789069 |
| GO:0030414 | peptidase inhibitor activity | IEA | -- |
Phenotypes for RECK Gene
- MGI mutant phenotypes for RECK:
- inferred from 5 alleles
- GenomeRNAi human phenotypes for RECK:
-
- Reduced mammosphere formation
- Decreased viability
- no effect
- Increased caspase activity
- Increased vaccinia virus (VACV) infection
- Increased gamma-H2AX phosphorylation
- Decreased homologous recombination repair frequency
- Decreased hepcidin::fluc mRNA expression
- Increased viability
- Increased viability with MLN4924 (a NAE inhibitor)
- Synthetic lethal with vaccinia virus (VACV) infection
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for RECK
-
CRISPR Products
-
OriGene CRISPR knockouts for RECK
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RECK
- genomics-online: gRNA clones - Search results for 85 available RECK gene related products
- Overview of 85 available RECK gene related products
- Applied Biological Materials CRISPR for RECK
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for RECK
- GenScript: Design CRISPR guide RNA sequences for RECK
miRNA for RECK Gene
- miRTarBase miRNAs that target RECK
-
- hsa-mir-373-3p (MIRT000606)
- hsa-mir-15b-5p (MIRT000607)
- hsa-mir-21-5p (MIRT000969)
- hsa-mir-222-3p (MIRT006728)
- hsa-mir-15a-5p (MIRT007090)
- hsa-mir-182-5p (MIRT007293)
- hsa-mir-335-5p (MIRT018129)
- hsa-mir-124-3p (MIRT022764)
- hsa-mir-103a-3p (MIRT027078)
- hsa-mir-16-5p (MIRT031373)
- hsa-mir-25-3p (MIRT053577)
- hsa-mir-374b-5p (MIRT054260)
- hsa-mir-221-3p (MIRT054649)
- hsa-mir-195-5p (MIRT107688)
- hsa-mir-424-5p (MIRT107689)
- hsa-mir-497-5p (MIRT107690)
- hsa-mir-562 (MIRT107692)
- hsa-mir-4524a-5p (MIRT107696)
- hsa-mir-4524b-5p (MIRT107698)
- hsa-mir-6838-5p (MIRT107699)
- hsa-mir-96-5p (MIRT438045)
- hsa-mir-92b-3p (MIRT438481)
- hsa-mir-7847-3p (MIRT454978)
- hsa-mir-1294 (MIRT454979)
- hsa-mir-6880-5p (MIRT454980)
- hsa-mir-6894-5p (MIRT454981)
- hsa-mir-7154-3p (MIRT454982)
- hsa-mir-765 (MIRT454983)
- hsa-mir-766-5p (MIRT454984)
- hsa-mir-5192 (MIRT454985)
- hsa-mir-4722-5p (MIRT454986)
- hsa-mir-6134 (MIRT454987)
- hsa-mir-7854-3p (MIRT454988)
- hsa-mir-4693-3p (MIRT454989)
- hsa-mir-4768-3p (MIRT454990)
- hsa-mir-3922-5p (MIRT454991)
- hsa-mir-940 (MIRT454992)
- hsa-mir-6893-5p (MIRT454993)
- hsa-mir-6808-5p (MIRT454994)
- hsa-mir-5586-3p (MIRT454995)
- hsa-mir-3714 (MIRT454996)
- hsa-mir-1271-5p (MIRT554826)
- hsa-mir-29b-2-5p (MIRT554827)
- hsa-mir-190a-3p (MIRT554828)
- hsa-mir-299-5p (MIRT554829)
- hsa-mir-410-3p (MIRT554830)
- hsa-mir-646 (MIRT554831)
- hsa-mir-618 (MIRT554832)
- hsa-mir-548x-3p (MIRT554833)
- hsa-mir-548j-3p (MIRT554834)
- hsa-mir-548aq-3p (MIRT554835)
- hsa-mir-548am-3p (MIRT554836)
- hsa-mir-548aj-3p (MIRT554837)
- hsa-mir-548ah-3p (MIRT554838)
- hsa-mir-548ae-3p (MIRT554839)
- hsa-mir-548z (MIRT554840)
- hsa-mir-548h-3p (MIRT554841)
- hsa-mir-548d-3p (MIRT554842)
- hsa-mir-548bb-3p (MIRT554843)
- hsa-mir-548ac (MIRT554844)
- hsa-mir-503-5p (MIRT554845)
- hsa-mir-135b-5p (MIRT731169)
- hsa-mir-15b-3p (MIRT731853)
- hsa-mir-409-3p (MIRT731975)
- hsa-mir-590-5p (MIRT733551)
- hsa-mir-183-5p (MIRT734040)
- mmu-mir-21a-3p (MIRT735209)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for RECK
- Browse OriGene Inhibitory RNA Products For RECK
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RECK
- genomics-online: shRNA clones - Search results for 85 available RECK gene related products
- Overview of 85 available RECK gene related products
Clone Products
- Sino Biological Human cDNA Clone for RECK
- Addgene plasmids for RECK
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RECK
- Applied Biological Materials Clones for RECK
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for RECK
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for RECK Gene
Localization for RECK Gene
Subcellular locations from UniProtKB/Swiss-Prot for RECK Gene
- Cell membrane; Lipid-anchor, GPI-anchor.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| extracellular | 5 |
| cytoskeleton | 1 |
| nucleus | 1 |
| endoplasmic reticulum | 1 |
| lysosome | 1 |
- Plasma membrane (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | TAS | -- |
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0016020 | membrane | TAS | 9789069 |
| GO:0031225 | anchored component of membrane | IEA | -- |
Pathways & Interactions for RECK Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Metabolism of proteins | ||
| 2 | MicroRNAs in cancer | ||
| 3 | Angiogenesis (CST) | ||
| 4 | Matrix Metalloproteinases | ||
| 5 | Post-translational modification- synthesis of GPI-anchored proteins | ||
Pathways by source for RECK Gene
3 Reactome pathways for RECK Gene
1 KEGG pathway for RECK Gene
1 Qiagen pathway for RECK Gene
1 Cell Signaling Technology pathway for RECK Gene
Interacting Proteins for RECK Gene
Selected Interacting proteins:
O95980-RECK_HUMAN
ENSP00000367202
for RECK Gene via
UniProtKB
IID
STRING
MINT
GPS-Prot Interaction Network for RECK
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001955 | blood vessel maturation | IEA | -- |
| GO:0006501 | C-terminal protein lipidation | TAS | -- |
| GO:0007566 | embryo implantation | IEA | -- |
| GO:0010466 | negative regulation of peptidase activity | IEA | -- |
| GO:0010951 | negative regulation of endopeptidase activity | IBA | -- |
No data available for SIGNOR curated interactions for RECK Gene
Transcripts for RECK Gene
mRNA/cDNA for RECK Gene
- (10) REFSEQ mRNAs :
- (12) Additional mRNA sequences :
- (115) Selected AceView cDNA sequences:
- (3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000377966 4888 bps (uc003zyv.4)
- ENST00000475774 1128 bps (uc064tag.1)
- ENST00000479053 1717 bps (uc064tah.1)
Unigene Clusters for RECK Gene
- Reversion-inducing-cysteine-rich protein with kazal motifs:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for RECK
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RECK
- genomics-online: gRNA clones - Search results for 85 available RECK gene related products
- Overview of 85 available RECK gene related products
- Applied Biological Materials CRISPR for RECK
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for RECK
- GenScript: Design CRISPR guide RNA sequences for RECK
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for RECK
- Browse OriGene Inhibitory RNA Products For RECK
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RECK
- genomics-online: shRNA clones - Search results for 85 available RECK gene related products
- Overview of 85 available RECK gene related products
Clone Products
- Sino Biological Human cDNA Clone for RECK
- Addgene plasmids for RECK
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RECK
- Applied Biological Materials Clones for RECK
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for RECK Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Dermis (Integumentary System)
- Zigzag Dermal Papilla Cells Dermal Papilla
- Guard Dermal Papilla Cells Dermal Papilla
- Detroit 551
-
Hair (Integumentary System)
- Zigzag Dermal Papilla Cells Dermal Papilla
- Guard Dermal Papilla Cells Dermal Papilla
- Intermediate Mesoderm (Gastrulation Derivatives)
- Kidney (Urinary System)
- Heart (Cardiovascular System)
- Fibroblasts
-
Ovary (Reproductive System)
This gene is overexpressed in Plasma (11.0), Skin (9.7), Cerebral cortex (8.6), and Serum (8.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for RECK Gene
NURSA nuclear receptor signaling pathways regulating expression of RECK Gene:
RECKSOURCE GeneReport for Unigene cluster for RECK Gene:
Hs.388918mRNA Expression by UniProt/SwissProt for RECK Gene:
O95980-RECK_HUMAN
Tissue specificity:
Expressed in various tissues and untransformed cells. It is undetectable in tumor-derived cell lines and oncogenically transformed cells.
Evidence on tissue expression from TISSUES for RECK Gene
- Lung(4.4)
- Intestine(2)
Primer Products
-
OriGene qPCR primer pairs for RECK
- genomics-online: primer clones - Search results for 85 available RECK gene related products
- Overview of 85 available RECK gene related products
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for RECK Gene
Orthologs for RECK Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | RECK 34 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | RECK 34 33 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | RECK 34 33 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | RECK 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | RECK 34 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Reck 16 34 33 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Reck 33 |
|
||
| chicken (Gallus gallus) |
Aves | RECK 34 33 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | RECK 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | reck 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | RECK 34 |
|
OneToOne | |
| fruit fly (Drosophila melanogaster) |
Insecta | Reck 34 33 |
|
OneToOne | |
| CG5392 35 |
|
|
|||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP010646 33 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToOne |
- Species where no ortholog for RECK was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Evolution for RECK Gene
- ENSEMBL:
- Gene Tree for RECK (if available)
- TreeFam:
- Gene Tree for RECK (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for RECK: view image
Paralogs for RECK Gene
No data available for Paralogs for RECK Gene
Variants for RECK Gene
| SNP ID | Clin | Chr 09 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000008795 | -- | 36,083,830(+) | G/T | intron_variant | |
| rs1000012615 | -- | 36,098,243(+) | A/G | genic_downstream_transcript_variant, intron_variant | |
| rs1000036547 | -- | 36,076,884(+) | C/A | intron_variant | |
| rs1000071334 | -- | 36,036,568(+) | C/G | upstream_transcript_variant | |
| rs1000089801 | -- | 36,111,533(+) | G/A | genic_downstream_transcript_variant, intron_variant |
Residual Variation Intolerance Score:
23.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
6.99;
80.01% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for RECK Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- RECK
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RECK Gene
Disorders for RECK Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| ovarian cancer |
|
|
| middle ear squamous cell carcinoma |
|
|
| middle ear carcinoma |
|
|
| wolfram syndrome |
|
|
| quebec platelet disorder |
|
|
Search RECK in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for RECK
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for RECK Gene
Publications for RECK Gene
- Regulation of matrix metalloproteinase-9 and inhibition of tumor invasion by the membrane-anchored glycoprotein RECK. (PMID: 9789069) Takahashi C … Noda M (Proceedings of the National Academy of Sciences of the United States of America 1998) 2 3 4 22 58
- Promoter polymorphisms in matrix metalloproteinases and their inhibitors: few associations with breast cancer susceptibility and progression. (PMID: 17033924) Lei H … Försti A (Breast cancer research and treatment 2007) 3 22 44 58
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 44 58
- Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey SD … DREAM investigators (Diabetes care 2010) 3 44 58
- RECK-mediated inhibition of glioma migration and invasion. (PMID: 20127710) Silveira Corrêa TC … Maria-Engler SS (Journal of cellular biochemistry 2010) 3 22 58
Products for RECK Gene
- R&D Systems Antibodies for RECK (RECK)
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- Browse Human Proteins and Enzymes
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
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- Custom Antibody ServicesOriGene Antibodies for RECK
- Browse OriGene ELISA Kits
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- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for RECK
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- OriGene qPCR primer pairs for RECK
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- OriGene ORF clones in human for RECK
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- GenScript: Design CRISPR guide RNA sequences for RECK
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
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- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
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- Sino Biological Human cDNA Clone for RECK
- Browse Sino Biological Recombinant Proteins
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- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for RECK
- Novus Biologicals proteins and lysates for RECK
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies
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- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for RECK (AFLGC-RECK)
- Cyagen custom Knockout/knockin (KOKI) mouse models for RECK
- Addgene plasmids for RECK
- antibodies-online: Search results for 82 available RECK Antibodies ranked by validation data
- Compare Top RECK Antibodies
- antibodies-online: Search results for 8 available RECK Elisa Kits ranked by validation data
- Compare Top RECK Elisa Kits
- Quality Products:
- antibodies-online: Search results for 4 available RECK Proteins ranked by validation data
- Compare Top RECK Proteins
- Quality Products:
- GeneTex RECK Antibody for RECK
- Search GeneTex for Proteins for RECK
- Santa Cruz Biotechnology (SCBT) Antibodies for RECK
- Search Santa Cruz Biotechnology (SCBT) for RECK siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for RECK
- Horizon Cell Lines for RECK
- genomics-online: cdna clones - Search results for 85 available RECK gene related products
- Overview of 85 available RECK gene related products
- orf clones - Search results for 85 available RECK gene related products
- Overview of 85 available RECK gene related products
- genomics-online: gRNA clones - Search results for 85 available RECK gene related products
- Overview of 85 available RECK gene related products
- genomics-online: primer clones - Search results for 85 available RECK gene related products
- Overview of 85 available RECK gene related products
- genomics-online: shRNA clones - Search results for 85 available RECK gene related products
- Overview of 85 available RECK gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RECK
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RECK
- GeneCopoeia miRNA 3'UTR Target clone products for RECK
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RECK
Sources for RECK Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt