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RCN3 (Reticulocalbin 3) is a Protein Coding gene. Diseases associated with RCN3 include Neonatal Respiratory Failure and Myopathy, Distal, 3. Gene Ontology (GO) annotations related to this gene include calcium ion binding. An important paralog of this gene is RCN1.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005509 | calcium ion binding | IEA,IDA | 16433634 |
GO:0005515 | protein binding | IPI | 16189514 |
GO:0046872 | metal ion binding | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005783 | endoplasmic reticulum | IBA,IDA | 16433634 |
GO:0005788 | endoplasmic reticulum lumen | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0009306 | protein secretion | IMP | 16433634 |
GO:0010952 | positive regulation of peptidase activity | IMP | 28939891 |
GO:0015031 | protein transport | ISS | -- |
GO:0032964 | collagen biosynthetic process | IMP | 28939891 |
GO:0036503 | ERAD pathway | IEA,ISS | -- |
ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b | · | 6c | ^ | 7 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | |||||||||||||||||||||
SP2: | - | ||||||||||||||||||||
SP3: | - |
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | RCN3 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | RCN3 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | RCN3 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Rcn3 30 17 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | RCN3 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Rcn3 30 |
|
||
Platypus (Ornithorhynchus anatinus) |
Mammalia | RCN3 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | RCN3 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | rcn3 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | rcn3 30 31 |
|
OneToOne | |
Fruit Fly (Drosophila melanogaster) |
Insecta | scf 31 |
|
OneToMany | |
Worm (Caenorhabditis elegans) |
Secernentea | calu-1 31 |
|
OneToMany | |
Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
ManyToMany | |
-- 31 |
|
ManyToMany | |||
CSA.6945 31 |
|
ManyToMany |
SNP ID | Clinical significance and condition | Chr 19 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs34654230 | - | p.Arg250Trp |
Disorder | Aliases | PubMed IDs |
---|---|---|
neonatal respiratory failure |
|
|
myopathy, distal, 3 |
|
|
enchondromatosis, multiple, ollier type |
|
|