Free for academic non-profit institutions. Other users need a Commercial license
Aliases for RCN3 Gene
Aliases for RCN3 Gene
External Ids for RCN3 Gene
- HGNC: 21145
- Entrez Gene: 57333
- Ensembl: ENSG00000142552
- UniProtKB: Q96D15
Previous GeneCards Identifiers for RCN3 Gene
- GC19P054706
- GC19P054722
- GC19P050030
- GC19P046407
Summaries for RCN3 Gene
GeneCards Summary for RCN3 Gene
RCN3 (Reticulocalbin 3) is a Protein Coding gene. Diseases associated with RCN3 include Neonatal Respiratory Failure and Myopathy, Distal, 3. Gene Ontology (GO) annotations related to this gene include calcium ion binding. An important paralog of this gene is RCN1.
UniProtKB/Swiss-Prot Summary for RCN3 Gene
-
Probable molecular chaperone assisting protein biosynthesis and transport in the endoplasmic reticulum (PubMed:16433634, PubMed:28939891). Required for the proper biosynthesis and transport of pulmonary surfactant-associated protein A/SP-A, pulmonary surfactant-associated protein D/SP-D and the lipid transporter ABCA3 (By similarity). By regulating both the proper expression and the degradation through the endoplasmic reticulum-associated protein degradation pathway of these proteins plays a crucial role in pulmonary surfactant homeostasis (By similarity). Has an anti-fibrotic activity by negatively regulating the secretion of type I and type III collagens (PubMed:28939891). This calcium-binding protein also transiently associates with immature PCSK6 and regulates its secretion (PubMed:16433634).
Additional gene information for RCN3 Gene
- HGNC(21145)
- Entrez Gene(57333)
- Ensembl(ENSG00000142552)
- UniProtKB(Q96D15)
- Open Targets Platform(ENSG00000142552)
- Search for RCN3 at DataMed
- Search for RCN3 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for RCN3 Gene
Genomics for RCN3 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for RCN3 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around RCN3 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for RCN3
- Top Transcription factor binding sites by QIAGEN in the RCN3 gene promoter:
-
- Bach1
- Bach2
- E2F
- E2F-1
- Egr-2
- Egr-4
- Elk-1
- ISGF-3
- Sp1
- STAT5A
Genomic Locations for RCN3 Gene
Genomic Locations for RCN3 Gene
- chr19:49,527,579-49,546,962
- (GRCh38/hg38)
- Size:
- 19,384 bases
- Orientation:
- Plus strand
- chr19:50,030,875-50,050,219
- (GRCh37/hg19)
- Size:
- 19,345 bases
- Orientation:
- Plus strand
Genomic View for RCN3 Gene
Genes around RCN3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19q13.33 by HGNC
- 19q13.33 by Entrez Gene
- 19q13.33 by Ensembl
RCN3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for RCN3 Gene
Proteins for RCN3 Gene
-
Protein details for RCN3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q96D15-RCN3_HUMAN
- Recommended name:
- Reticulocalbin-3
- Protein Accession:
- Q96D15
- Q9HBZ8
Protein attributes for RCN3 Gene
- Size:
- 328 amino acids
- Molecular mass:
- 37493 Da
- Quaternary structure:
-
- Interacts with PCSK6 (immature form including the propeptide); probably involved in the maturation and the secretion of PCSK6.
Protein Expression for RCN3 Gene
Post-translational modifications for RCN3 Gene
Other Protein References for RCN3 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for RCN3
- Novus Biologicals Antibodies for RCN3
- Invitrogen Antibodies for RCN3 (AFLGC-RCN3)
- antibodies-online: Show 37 available RCN3 Antibodies ranked by validation data
-
Biorbyt antibodies for RCN3
Protein Products
- G Biosciences Human Reticulocalbin-3/RCN3, Liquid
- Search Origene for MassSpec and Protein Over-expression Lysates for RCN3
- Origene Custom Protein Services for RCN3
- Sino Biological Cell Lysates for RCN3
- Sino Biological Recombinant Proteins for RCN3
- ProSpec Recombinant Proteins for RCN3
- antibodies-online: Search results for available RCN3 related products ranked by validation data
-
Signalway Proteins for RCN3
-
ProSci Proteins for RCN3
No data available for DME Specific Peptides for RCN3 Gene
Domains & Families for RCN3 Gene
Gene Families for RCN3 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted intracellular proteins
- Predicted membrane proteins
Protein Domains for RCN3 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for RCN3 Gene
- GenScript: Design optimal peptide antigens:
-
- EF-hand calcium-binding protein RLP49 (RCN3_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q96D15- Family:
-
- Belongs to the CREC family.
Function for RCN3 Gene
Molecular function for RCN3 Gene
- UniProtKB/Swiss-Prot Function:
- Probable molecular chaperone assisting protein biosynthesis and transport in the endoplasmic reticulum (PubMed:16433634, PubMed:28939891). Required for the proper biosynthesis and transport of pulmonary surfactant-associated protein A/SP-A, pulmonary surfactant-associated protein D/SP-D and the lipid transporter ABCA3 (By similarity). By regulating both the proper expression and the degradation through the endoplasmic reticulum-associated protein degradation pathway of these proteins plays a crucial role in pulmonary surfactant homeostasis (By similarity). Has an anti-fibrotic activity by negatively regulating the secretion of type I and type III collagens (PubMed:28939891). This calcium-binding protein also transiently associates with immature PCSK6 and regulates its secretion (PubMed:16433634).
- UniProtKB/Swiss-Prot Induction:
- Down-regulated by aldosterone (at protein level). No effect at the transcript level.
Phenotypes From GWAS Catalog for RCN3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005509 | calcium ion binding | IEA,IDA | 16433634 |
| GO:0005515 | protein binding | IPI | 16189514 |
| GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for RCN3 Gene
- MGI mutant phenotypes for RCN3:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for RCN3:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for RCN3 - Select products 50% OFF >
- * RCN3 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for RCN3
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RCN3
-
Santa Cruz Biotechnology (SCBT) CRISPR for RCN3
miRNA for RCN3 Gene
- miRTarBase miRNAs that target RCN3
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for RCN3
- Browse OriGene Inhibitory RNA Products For RCN3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RCN3
Clone Products
- Applied Biological Materials (abm): Clones for RCN3 - Select products 50% OFF >
- * RCN3 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for RCN3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RCN3
Cell Line Products
-
Horizon Cell Lines for RCN3
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for RCN3 Gene
Localization for RCN3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for RCN3 Gene
- Endoplasmic reticulum lumen.
| Compartment | Confidence |
|---|---|
| endoplasmic reticulum | 5 |
| extracellular | 2 |
| mitochondrion | 2 |
| plasma membrane | 1 |
| cytoskeleton | 1 |
| nucleus | 1 |
| cytosol | 1 |
| golgi apparatus | 1 |
| peroxisome | 0 |
| lysosome | 0 |
- Endoplasmic reticulum (2)
- Vesicles (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005783 | endoplasmic reticulum | IBA,IDA | 16433634 |
| GO:0005788 | endoplasmic reticulum lumen | IEA | -- |
Pathways & Interactions for RCN3 Gene
Interacting Proteins for RCN3 Gene
Selected Interacting proteins:
Q96D15-RCN3_HUMAN
ENSP00000270645
for RCN3 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for RCN3
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0009306 | protein secretion | IMP | 16433634 |
| GO:0010952 | positive regulation of peptidase activity | IMP | 28939891 |
| GO:0015031 | protein transport | ISS | -- |
| GO:0032964 | collagen biosynthetic process | IMP | 28939891 |
| GO:0036503 | ERAD pathway | IEA,ISS | -- |
No data available for Pathways by source and SIGNOR curated interactions for RCN3 Gene
Drugs & Compounds for RCN3 Gene
No Compound Related Data Available
Drug Products
- G Biosciences Human Reticulocalbin-3/RCN3, Liquid
Transcripts for RCN3 Gene
mRNA/cDNA for RCN3 Gene
- 1 REFSEQ mRNAs :
- 4 NCBI additional mRNA sequence :
- 5 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000270645 1469 nts (view in UCSC)
- ENST00000593483 595 nts (view in UCSC)
- ENST00000593644 223 nts (view in UCSC)
- ENST00000597801 549 nts (view in UCSC)
- ENST00000598833 607 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for RCN3 - Select products 50% OFF >
- * RCN3 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for RCN3
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RCN3
-
Santa Cruz Biotechnology (SCBT) CRISPR for RCN3
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for RCN3
- Browse OriGene Inhibitory RNA Products For RCN3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RCN3
Clone Products
- Applied Biological Materials (abm): Clones for RCN3 - Select products 50% OFF >
- * RCN3 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for RCN3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RCN3
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b | · | 6c | ^ | 7 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||||||||||||
| SP2: | - | ||||||||||||||||||||
| SP3: | - |
Relevant External Links for RCN3 Gene
- GeneLoc Exon Structure for
- RCN3
Expression for RCN3 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Smooth Muscle (Muscoskeletal System)
- Neural Crest (Gastrulation Derivatives)
- Paraxial Mesoderm (Gastrulation Derivatives)
This gene is overexpressed in Bone marrow stromal cell (56.9).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for RCN3 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for RCN3
SOURCE GeneReport for Unigene cluster for RCN3 Gene:
Hs.567550mRNA Expression by UniProt/SwissProt for RCN3 Gene:
Q96D15-RCN3_HUMAN
Tissue specificity:
Widely expressed.
Evidence on tissue expression from TISSUES for RCN3 Gene
- Lung(4.3)
- Nervous system(4.3)
- Liver(4.1)
Primer Products
-
OriGene qPCR primer pairs for RCN3
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for RCN3 Gene
Orthologs for RCN3 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | RCN3 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | RCN3 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | RCN3 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Rcn3 30 17 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | RCN3 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Rcn3 30 |
|
||
| Platypus (Ornithorhynchus anatinus) |
Mammalia | RCN3 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | RCN3 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | rcn3 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | rcn3 30 31 |
|
OneToOne | |
| Fruit Fly (Drosophila melanogaster) |
Insecta | scf 31 |
|
OneToMany | |
| Worm (Caenorhabditis elegans) |
Secernentea | calu-1 31 |
|
OneToMany | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
ManyToMany | |
| -- 31 |
|
ManyToMany | |||
| CSA.6945 31 |
|
ManyToMany |
- Species where no ortholog for RCN3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for RCN3 Gene
- ENSEMBL:
- Gene Tree for RCN3 (if available)
- TreeFam:
- Gene Tree for RCN3 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for RCN3: view image
Paralogs for RCN3 Gene
Variants for RCN3 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for RCN3 Gene
| SNP ID | Clinical significance and condition | Chr 19 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs34654230 | - | p.Arg250Trp |
Residual Variation Intolerance Score:
85.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
6.71;
78.66% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for RCN3 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- RCN3
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RCN3 Gene
Disorders for RCN3 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| neonatal respiratory failure |
|
|
| myopathy, distal, 3 |
|
|
| enchondromatosis, multiple, ollier type |
|
|
Search RCN3 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for RCN3
No data available for UniProtKB/Swiss-Prot and Genatlas for RCN3 Gene
Publications for RCN3 Gene
- A proteomic approach reveals transient association of reticulocalbin-3, a novel member of the CREC family, with the precursor of subtilisin-like proprotein convertase, PACE4. (PMID: 16433634) Tsuji A … Matsuda Y (The Biochemical journal 2006) 3 4 23
- Differential Proteomics Identifies Reticulocalbin-3 as a Novel Negative Mediator of Collagen Production in Human Cardiac Fibroblasts. (PMID: 28939891) Martínez-Martínez E … López-Andrés N (Scientific reports 2017) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark HF … Gray A (Genome research 2003) 3 4
- Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. (PMID: 10931946) Hu RM … Chen JL (Proceedings of the National Academy of Sciences of the United States of America 2000) 3 4
ExternalLinks
Products for RCN3 Gene
- Custom Antibody ServicesOriGene Antibodies for RCN3
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for MassSpec and Protein Over-expression Lysates for RCN3
- Origene Custom Protein Services for RCN3
- Origene shrna, sirna, and RNAi products in human, mouse, rat for RCN3
- Browse OriGene Inhibitory RNA Products For RCN3
- OriGene qPCR primer pairs for RCN3
- OriGene CRISPR knockouts for RCN3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For RCN3
- Sino Biological Human cDNA Clone for RCN3
- Sino Biological Cell Lysates for RCN3
- Sino Biological Recombinant Proteins for RCN3
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse Recombinant Proteins
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for RCN3
- Novus Biologicals proteins and lysates for RCN3
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- VectorBuilder Custom and pre-made DNA vectors for RCN3 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for RCN3 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for RCN3 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for RCN3 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for RCN3
- antibodies-online: Show 37 available RCN3 Antibodies ranked by validation data
- antibodies-online: Search results for available RCN3 related products ranked by validation data
- antibodies-online: Search results for available RCN3 related products ranked by validation data
- Search for RCN3 Antibodies at ProSci
- Custom Antibody Services
- ProSci Proteins for RCN3
- Horizon Cell Lines for RCN3
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RCN3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RCN3
- Search GeneCopoeia for miRNA 3'UTR Target clone products for RCN3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RCN3
- Biorbyt antibodies for RCN3
- Signalway Proteins for RCN3
Sources for RCN3 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB