Aliases for RCN1 Gene
External Ids for RCN1 Gene
Previous HGNC Symbols for RCN1 Gene
Previous GeneCards Identifiers for RCN1 Gene
Reticulocalbin 1 is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. High conservation of amino acid residues outside of these motifs, in comparison to mouse reticulocalbin, is consistent with a possible biochemical function besides that of calcium binding. In human endothelial and prostate cancer cell lines this protein localizes to the plasma membrane.[provided by RefSeq, Jan 2009]
GeneCards Summary for RCN1 Gene
RCN1 (Reticulocalbin 1) is a Protein Coding gene. Diseases associated with RCN1 include Nephrogenic Systemic Fibrosis. Gene Ontology (GO) annotations related to this gene include calcium ion binding. An important paralog of this gene is ENSG00000285283.
UniProtKB/Swiss-Prot for RCN1 Gene
May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment.