Aliases for RCC2 Gene
External Ids for RCC2 Gene
Previous GeneCards Identifiers for RCC2 Gene
The protein encoded by this gene is a guanine exchange factor that is active on RalA, a small GTPase. The encoded protein and RalA are both essential for proper kinetochore-microtubule function in early mitosis. This protein has been shown to be a biomarker for colorectal cancer. [provided by RefSeq, Oct 2016]
GeneCards Summary for RCC2 Gene
RCC2 (Regulator Of Chromosome Condensation 2) is a Protein Coding gene. Among its related pathways are DNA Damage and Signaling by Rho GTPases. Gene Ontology (GO) annotations related to this gene include protein domain specific binding. An important paralog of this gene is RPGR.
UniProtKB/Swiss-Prot for RCC2 Gene
Required for completion of mitosis and cytokinesis. May function as a guanine nucleotide exchange factor for the small GTPase RAC1.