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This gene encodes a protein containing two C-terminal BTB/POZ domains that is related to regulator of chromosome condensation (RCC). The encoded protein may act as a guanine nucleotide exchange factor. This gene is observed to be lost or underexpressed in prostate cancers. There is a pseudogene of this gene on chromosome 10. Alternative splicing results in multiple transcript v... See more...
Aliases for RCBTB2 Gene
Aliases for RCBTB2 Gene
External Ids for RCBTB2 Gene
- HGNC: 1914
- Entrez Gene: 1102
- Ensembl: ENSG00000136161
- OMIM: 603524
- UniProtKB: O95199
Previous HGNC Symbols for RCBTB2 Gene
- CHC1L
Previous GeneCards Identifiers for RCBTB2 Gene
- GC13M047962
- GC13M049063
- GC13M029855
Summaries for RCBTB2 Gene
-
This gene encodes a protein containing two C-terminal BTB/POZ domains that is related to regulator of chromosome condensation (RCC). The encoded protein may act as a guanine nucleotide exchange factor. This gene is observed to be lost or underexpressed in prostate cancers. There is a pseudogene of this gene on chromosome 10. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]
GeneCards Summary for RCBTB2 Gene
RCBTB2 (RCC1 And BTB Domain Containing Protein 2) is a Protein Coding gene. Diseases associated with RCBTB2 include Pleomorphic Lipoma and Postencephalitic Parkinson Disease. Gene Ontology (GO) annotations related to this gene include Ran guanyl-nucleotide exchange factor activity. An important paralog of this gene is RCBTB1.
Additional gene information for RCBTB2 Gene
- HGNC(1914)
- Entrez Gene(1102)
- Ensembl(ENSG00000136161)
- OMIM(603524)
- UniProtKB(O95199)
- Open Targets Platform(ENSG00000136161)
- Search for RCBTB2 at DataMed
- Search for RCBTB2 at HumanCyc
No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for RCBTB2 Gene
Genomics for RCBTB2 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for RCBTB2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around RCBTB2 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for RCBTB2
- Top Transcription factor binding sites by QIAGEN in the RCBTB2 gene promoter:
-
- C/EBPalpha
- E2F
- E2F-1
- ER-alpha
- Evi-1
- FOXI1
- HFH-3
- IRF-1
- PPAR-alpha
- ZID
Genomic Locations for RCBTB2 Gene
Genomic Locations for RCBTB2 Gene
- chr13:48,488,959-48,535,997
- (GRCh38/hg38)
- Size:
- 47,039 bases
- Orientation:
- Minus strand
- chr13:49,063,095-49,107,369
- (GRCh37/hg19)
- Size:
- 44,275 bases
- Orientation:
- Minus strand
Genomic View for RCBTB2 Gene
Genes around RCBTB2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 13q14.2 by HGNC
- 13q14.2 by Entrez Gene
- 13q14.2 by Ensembl
RCBTB2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for RCBTB2 Gene
Proteins for RCBTB2 Gene
-
Protein details for RCBTB2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O95199-RCBT2_HUMAN
- Recommended name:
- RCC1 and BTB domain-containing protein 2
- Protein Accession:
- O95199
- B2RDW8
Protein attributes for RCBTB2 Gene
- Size:
- 551 amino acids
- Molecular mass:
- 60315 Da
- Quaternary structure:
- No Data Available
Protein Expression for RCBTB2 Gene
Post-translational modifications for RCBTB2 Gene
Other Protein References for RCBTB2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
-
- XP_011533196.1
- XP_016875858.1
- XP_016875859.1
- XP_016875860.1
- XP_016875861.1
- XP_016875863.1
- XP_016875864.1
- XP_016875865.1
- XP_016875866.1
- XP_016875868.1
- NP_001259.1
- NP_001273759.1
- NP_001273760.1
- NP_001273761.1
- NP_001339353.1
- NP_001339354.1
- NP_001339355.1
- NP_001339356.1
- NP_001339357.1
- NP_001339358.1
- NP_001339359.1
- NP_001339360.1
Antibody Products
- LifeSpan BioSciences RCBTB2 Antibody
- Creative Diagnostics Anti-RCBTB2 monoclonal antibody
-
Custom Antibody ServicesOriGene Antibodies for RCBTB2
- Novus Biologicals Antibodies for RCBTB2
-
Abcam antibodies for RCBTB2
- Invitrogen Antibodies for RCBTB2 (AFLGC-Rcbtb2)
Protein Products
-
OriGene Purified Proteins for RCBTB2
- Search Origene for MassSpec and Protein Over-expression Lysates for RCBTB2
- Origene Custom Protein Services for RCBTB2
- antibodies-online: Show 6 available RCBTB2 Proteins ranked by validation data
- Compare Top RCBTB2 Proteins
-
Quality Products:
-
Abcam proteins for RCBTB2
Assay Products
- antibodies-online: Show 6 available RCBTB2 Elisa Kits ranked by validation data
- Compare Top RCBTB2 Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for RCBTB2 Gene
Domains & Families for RCBTB2 Gene
Gene Families for RCBTB2 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for RCBTB2 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for RCBTB2 Gene
- GenScript: Design optimal peptide antigens:
-
- cDNA FLJ16324 fis, clone SPLEN2042920, highly similar to RCC1 and BTB domain-containing protein 2 (B3KVB1_HUMAN)
- cDNA FLJ59946, highly similar to RCC1 and BTB domain-containing protein 2 (B4DPP7_HUMAN)
- cDNA FLJ58545, highly similar to RCC1 and BTB domain-containing protein 2 (B4DWG0_HUMAN)
- cDNA FLJ54251, highly similar to RCC1 and BTB domain-containing protein 2 (B4E372_HUMAN)
- Regulator of chromosome condensation and BTB domain-containing protein 2 (RCBT2_HUMAN)
Graphical View of Domain Structure for InterPro Entry
O95199UniProtKB/Swiss-Prot:
RCBT2_HUMAN :- The BTB domain might play a role in targeting to acrosomal vesicles.
- Domain:
-
- The BTB domain might play a role in targeting to acrosomal vesicles.
Function for RCBTB2 Gene
Phenotypes From GWAS Catalog for RCBTB2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005087 | Ran guanyl-nucleotide exchange factor activity | TAS | 9806834 |
| GO:0005515 | protein binding | IPI | 25416956 |
Phenotypes for RCBTB2 Gene
- MGI mutant phenotypes for RCBTB2:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for RCBTB2:
Animal Models for RCBTB2 Gene
- MGI Knock Outs for RCBTB2:
-
- Rcbtb2 Rcbtb2<tm1.1Xyw>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for RCBTB2 - Select products 50% OFF >
- * RCBTB2 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
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-
OriGene CRISPR knockouts for RCBTB2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RCBTB2
-
Santa Cruz Biotechnology (SCBT) CRISPR for RCBTB2
miRNA for RCBTB2 Gene
- miRTarBase miRNAs that target RCBTB2
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for RCBTB2
- Browse OriGene Inhibitory RNA Products For RCBTB2
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Clone Products
- Applied Biological Materials (abm): Clones for RCBTB2 - Select products 50% OFF >
- * RCBTB2 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
- MG208751
- MG217393
- MR208751
- MR208751L3
- MR208751L4
- MR217393
- MR217393L3
- MR217393L4
- RC206560
- RC206560L1
- RC206560L2
- RC206560L3
- RC206560L4
- RC237115
- RC238726
- RC238884
- RG206560
- RR209344
- RR209344L3
- RR209344L4
- MR208751L3V
- MR208751L4V
- MR217393L3V
- MR217393L4V
- RC206560L1V
- RC206560L2V
- RC206560L3V
- RC206560L4V
- RR209344L3V
- RR209344L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for RCBTB2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RCBTB2
No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for RCBTB2 Gene
Localization for RCBTB2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for RCBTB2 Gene
- Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Mainly found in the acrosomal cap region. {ECO:0000250 UniProtKB:Q99LJ7}.
| Compartment | Confidence |
|---|---|
| cytosol | 3 |
| plasma membrane | 1 |
| extracellular | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| nucleus | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| golgi apparatus | 1 |
- Golgi apparatus (2)
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001669 | acrosomal vesicle | IEA | -- |
| GO:0031410 | cytoplasmic vesicle | IEA | -- |
Pathways & Interactions for RCBTB2 Gene
Interacting Proteins for RCBTB2 Gene
Selected Interacting proteins:
O95199-RCBT2_HUMAN
ENSP00000389910
for RCBTB2 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for RCBTB2
No data available for Pathways by source and SIGNOR curated interactions for RCBTB2 Gene
Transcripts for RCBTB2 Gene
mRNA/cDNA for RCBTB2 Gene
- 12 REFSEQ mRNAs :
- 13 NCBI additional mRNA sequence :
- 7 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000344532 3232 nts (view in UCSC)
- ENST00000430805 3179 nts (view in UCSC)
- ENST00000462703 553 nts (view in UCSC)
- ENST00000481144 670 nts (view in UCSC)
- ENST00000544492 2622 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for RCBTB2 - Select products 50% OFF >
- * RCBTB2 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for RCBTB2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RCBTB2
-
Santa Cruz Biotechnology (SCBT) CRISPR for RCBTB2
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for RCBTB2
- Browse OriGene Inhibitory RNA Products For RCBTB2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RCBTB2
Clone Products
- Applied Biological Materials (abm): Clones for RCBTB2 - Select products 50% OFF >
- * RCBTB2 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
- MG208751
- MG217393
- MR208751
- MR208751L3
- MR208751L4
- MR217393
- MR217393L3
- MR217393L4
- RC206560
- RC206560L1
- RC206560L2
- RC206560L3
- RC206560L4
- RC237115
- RC238726
- RC238884
- RG206560
- RR209344
- RR209344L3
- RR209344L4
- MR208751L3V
- MR208751L4V
- MR217393L3V
- MR217393L4V
- RC206560L1V
- RC206560L2V
- RC206560L3V
- RC206560L4V
- RR209344L3V
- RR209344L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for RCBTB2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RCBTB2
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | · | 3c | · | 3d | · | 3e | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | · | 9c | · | 9d | ^ | 10a | · | 10b | ^ | 11a | · | 11b | · | 11c | · | 11d | ^ | 12a | · | 12b | ^ | 13 | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP8: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP9: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP11: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP12: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP13: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||
| SP14: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP15: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP16: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP17: |
| ExUns: | 14 | ^ | 15a | · | 15b | ^ | 16a | · | 16b | ^ | 17 | ^ | 18 | ^ | 19a | · | 19b | ^ | 20a | · | 20b | ^ | 21 | ^ | 22a | · | 22b | · | 22c |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | ||||||||||||||||||||||||
| SP2: | - | - | - | - | - | ||||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||||||
| SP4: | |||||||||||||||||||||||||||||
| SP5: | |||||||||||||||||||||||||||||
| SP6: | |||||||||||||||||||||||||||||
| SP7: | |||||||||||||||||||||||||||||
| SP8: | |||||||||||||||||||||||||||||
| SP9: | |||||||||||||||||||||||||||||
| SP10: | |||||||||||||||||||||||||||||
| SP11: | |||||||||||||||||||||||||||||
| SP12: | |||||||||||||||||||||||||||||
| SP13: | |||||||||||||||||||||||||||||
| SP14: | |||||||||||||||||||||||||||||
| SP15: | |||||||||||||||||||||||||||||
| SP16: | - | - | - | ||||||||||||||||||||||||||
| SP17: | - |
Relevant External Links for RCBTB2 Gene
- GeneLoc Exon Structure for
- RCBTB2
Expression for RCBTB2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Liver (Hepatobiliary System)
- Periportal Hepatocytes Liver Lobule
- Epiblast (Early Embryonic Tissues)
- Germ Cells (Reproductive System)
- Gonad
This gene is overexpressed in Frontal cortex (48.1).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for RCBTB2 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for RCBTB2
SOURCE GeneReport for Unigene cluster for RCBTB2 Gene:
Hs.652712Evidence on tissue expression from TISSUES for RCBTB2 Gene
- Nervous system(4.9)
- Blood(2.4)
- Skin(2.1)
Primer Products
-
OriGene qPCR primer pairs for RCBTB2
-
OriGene qPCR primer pairs and template standards for RCBTB2
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for RCBTB2 Gene
Orthologs for RCBTB2 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Dog (Canis familiaris) |
Mammalia | RCBTB2 31 |
|
OneToOne | |
| Chimpanzee (Pan troglodytes) |
Mammalia | RCBTB2 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | RCBTB2 30 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | RCBTB2 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Rcbtb2 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Rcbtb2 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | RCBTB2 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | RCBTB2 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | RCBTB2 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | rcbtb2 30 |
|
||
| Str.15041 30 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | chc1l-A-prov 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | rcbtb2 30 31 |
|
OneToOne | |
| Fruit Fly (Drosophila melanogaster) |
Insecta | ca 31 |
|
OneToMany | |
| Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | SRM1 31 |
|
OneToMany | |
| FMP25 33 |
|
|
|||
| Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.9432 31 |
|
OneToMany |
- Species where no ortholog for RCBTB2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for RCBTB2 Gene
- ENSEMBL:
- Gene Tree for RCBTB2 (if available)
- TreeFam:
- Gene Tree for RCBTB2 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for RCBTB2: view image
Paralogs for RCBTB2 Gene
(2) SIMAP similar genes for RCBTB2 Gene using alignment to 4 proteins:
- RCBT2_HUMAN
- B4DPP7_HUMAN
- B4DWG0_HUMAN
- B4E372_HUMAN
Pseudogenes.org Pseudogenes for RCBTB2 Gene
Variants for RCBTB2 Gene
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2520493 | CNV | deletion | 19546169 |
| esv3352426 | CNV | insertion | 20981092 |
| esv3384312 | CNV | duplication | 20981092 |
| nsv832602 | CNV | loss | 17160897 |
| nsv832604 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
20% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.21;
24.32% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for RCBTB2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- RCBTB2
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RCBTB2 Gene
Disorders for RCBTB2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| pleomorphic lipoma |
|
|
| postencephalitic parkinson disease |
|
|
| cone-rod dystrophy 2 |
|
|
Search RCBTB2 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for RCBTB2
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for RCBTB2 Gene
Publications for RCBTB2 Gene
- cDNA cloning, gene characterization and 13q14.3 chromosomal assignment of CHC1-L, a chromosome condensation regulator-like guanine nucleotide exchange factor. (PMID: 9806834) Devilder MC … Moisan JP (Genomics 1998) 2 3 4
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 41
- The DNA sequence and analysis of human chromosome 13. (PMID: 15057823) Dunham A … Ross MT (Nature 2004) 3 4
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
ExternalLinks
Products for RCBTB2 Gene
- Custom Antibody ServicesOriGene Antibodies for RCBTB2
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for RCBTB2
- Search Origene for MassSpec and Protein Over-expression Lysates for RCBTB2
- Origene Custom Protein Services for RCBTB2
- Origene shrna, sirna, and RNAi products in human, mouse, rat for RCBTB2
- Browse OriGene Inhibitory RNA Products For RCBTB2
- OriGene qPCR primer pairs for RCBTB2
- OriGene qPCR primer pairs and template standards for RCBTB2
- OriGene CRISPR knockouts for RCBTB2
- MG208751
- MG217393
- MR208751
- MR208751L3
- MR208751L4
- MR217393
- MR217393L3
- MR217393L4
- RC206560
- RC206560L1
- RC206560L2
- RC206560L3
- RC206560L4
- RC237115
- RC238726
- RC238884
- RG206560
- RR209344
- RR209344L3
- RR209344L4
- MR208751L3V
- MR208751L4V
- MR217393L3V
- MR217393L4V
- RC206560L1V
- RC206560L2V
- RC206560L3V
- RC206560L4V
- RR209344L3V
- RR209344L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- Invitrogen Antibodies for RCBTB2 (AFLGC-Rcbtb2)
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- VectorBuilder Viral vectors for RCBTB2 (ie. lentivirus, AAV, adenovirus)
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- VectorBuilder Stable cell line generation for RCBTB2
- antibodies-online: Show 10 available RCBTB2 Antibodies ranked by validation data
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- Horizon Cell Lines for RCBTB2
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Sources for RCBTB2 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
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- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB