Aliases for RBPMS2 Gene
External Ids for RBPMS2 Gene
Previous GeneCards Identifiers for RBPMS2 Gene
The protein encoded by this gene is a member of the RNA recognition motif (RRM)-containing protein family and is involved in the development and dedifferentiation of digestive smooth muscle cells. The encoded protein functions as a homodimer and indirectly inhibits the bone morphogenetic protein pathway. [provided by RefSeq, Aug 2016]
GeneCards Summary for RBPMS2 Gene
RBPMS2 (RNA Binding Protein, MRNA Processing Factor 2) is a Protein Coding gene. Diseases associated with RBPMS2 include Megacystis-Microcolon-Intestinal Hypoperistalsis Syndrome. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and nucleotide binding. An important paralog of this gene is RBPMS.
UniProtKB/Swiss-Prot Summary for RBPMS2 Gene
RNA-binding protein involved in the regulation of smooth muscle cell differentiation and proliferation in the gastrointestinal system (PubMed:25064856). Binds NOG mRNA, the major inhibitor of the bone morphogenetic protein (BMP) pathway. Mediates an increase of NOG mRNA levels, thereby contributing to the negative regulation of BMP signaling pathway and promoting reversible dedifferentiation and proliferation of smooth muscle cells (By similarity).