Aliases for RBPJL Gene
External Ids for RBPJL Gene
Previous HGNC Symbols for RBPJL Gene
Previous GeneCards Identifiers for RBPJL Gene
This gene encodes a member of the suppressor of hairless protein family. A similar protein in mouse is a transcription factor that binds to DNA sequences almost identical to that bound by the Notch receptor signaling pathway transcription factor recombining binding protein J. The mouse protein has been shown to activate transcription in concert with Epstein-Barr virus nuclear antigen-2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
GeneCards Summary for RBPJL Gene
RBPJL (Recombination Signal Binding Protein For Immunoglobulin Kappa J Region Like) is a Protein Coding gene. Diseases associated with RBPJL include Diabetes Mellitus, Noninsulin-Dependent. Among its related pathways are Spinocerebellar ataxia and Th17 cell differentiation. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding. An important paralog of this gene is RBPJ.
UniProtKB/Swiss-Prot Summary for RBPJL Gene
Putative transcription factor, which cooperates with EBNA2 to activate transcription.