This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding p... See more...

Aliases for RBP4 Gene

Aliases for RBP4 Gene

  • Retinol Binding Protein 4 2 3 5
  • Plasma Retinol-Binding Protein 3 4
  • Retinol-Binding Protein 4 3 4
  • PRBP 3 4
  • RBP 3 4
  • Retinol-Binding Protein 4, Interstitial 3
  • Retinol-Binding Protein 4, Plasma 2
  • Retinol Binding Protein 4, Plasma 3
  • MCOPCB10 3
  • RDCCAS 3
  • RBP4 5

External Ids for RBP4 Gene

Previous GeneCards Identifiers for RBP4 Gene

  • GC10M094244
  • GC10M094585
  • GC10M095482
  • GC10M095016
  • GC10M095341
  • GC10M088979

Summaries for RBP4 Gene

Entrez Gene Summary for RBP4 Gene

  • This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells. [provided by RefSeq, Jul 2008]

GeneCards Summary for RBP4 Gene

RBP4 (Retinol Binding Protein 4) is a Protein Coding gene. Diseases associated with RBP4 include Retinal Dystrophy, Iris Coloboma, And Comedogenic Acne Syndrome and Microphthalmia, Isolated, With Coloboma 10. Among its related pathways are Metabolism of water-soluble vitamins and cofactors and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include protein heterodimerization activity and retinol binding.

UniProtKB/Swiss-Prot Summary for RBP4 Gene

  • Retinol-binding protein that mediates retinol transport in blood plasma (PubMed:5541771). Delivers retinol from the liver stores to the peripheral tissues (Probable). Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane (PubMed:22665496).

Gene Wiki entry for RBP4 Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for RBP4 Gene

Genomics for RBP4 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for RBP4 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10J093601 Promoter 1.4 EPDnew Ensembl 256.9 +0.6 643 1.4 SSRP1 CEBPA ATF3 CHD4 KLF11 THAP11 FOXA2 KDM6A RXRA SMAD4 RBP4 NONHSAG006547.2 RPL17P34 ENSG00000273450 NOC3L NONHSAG006546.2 FFAR4
GH10J093581 Enhancer 0.6 Ensembl 17.4 +20.7 20701 0.8 JUND MYNN RFX5 RFX1 ATF2 CSDE1 CREB1 ZNF239 POLR2A BMI1 RBP4 PDE6C NONHSAG006546.2 FFAR4
GH10J093566 Promoter 1.2 EPDnew Ensembl 5.6 +35.0 35043 1.4 ZNF600 CEBPA ZNF10 ZIC2 ZNF341 SIN3A KLF16 GLI4 SPI1 MYC FFAR4 RBP4 NONHSAG006546.2
GH10J093591 Enhancer 0.7 Ensembl ENCODE 7.1 +10.1 10143 1.6 SSRP1 RXRA RBM22 SPI1 MAX PAF1 IKZF1 POLR2A RBFOX2 NR2F2 PDE6C FFAR4 RBP4 NONHSAG006546.2
GH10J093541 Enhancer 0.8 ENCODE 5.6 +59.1 59098 1.1 ZNF654 ZNF600 NFIC CTCF RXRA RAD21 ZBTB48 ZNF2 ZNF189 MAX lnc-CEP55-1 FRA10AC1 PDE6C HELLS RBP4 piR-55194-053 FFAR4 CEP55
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around RBP4 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for RBP4

Top Transcription factor binding sites by QIAGEN in the RBP4 gene promoter:
  • AP-2alpha
  • AP-2alphaA
  • AP-2beta
  • AP-2gamma
  • PPAR-gamma1
  • PPAR-gamma2

Genomic Locations for RBP4 Gene

Latest Assembly
chr10:93,591,687-93,601,744
(GRCh38/hg38)
Size:
10,058 bases
Orientation:
Minus strand

Previous Assembly
chr10:95,351,451-95,361,501
(GRCh37/hg19 by Entrez Gene)
Size:
10,051 bases
Orientation:
Minus strand

chr10:95,351,444-95,361,501
(GRCh37/hg19 by Ensembl)
Size:
10,058 bases
Orientation:
Minus strand

Genomic View for RBP4 Gene

Genes around RBP4 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RBP4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RBP4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RBP4 Gene

Proteins for RBP4 Gene

  • Protein details for RBP4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P02753-RET4_HUMAN
    Recommended name:
    Retinol-binding protein 4
    Protein Accession:
    P02753
    Secondary Accessions:
    • D3DR38
    • O43478
    • O43479
    • Q5VY24
    • Q8WWA3
    • Q9P178

    Protein attributes for RBP4 Gene

    Size:
    201 amino acids
    Molecular mass:
    23010 Da
    Quaternary structure:
    • Interacts with TTR (PubMed:5541771, PubMed:7754382, PubMed:10052934, PubMed:19021760). Interaction with TTR prevents its loss by filtration through the kidney glomeruli (Probable). Interacts with STRA6 (PubMed:22665496, PubMed:25910211).
    SequenceCaution:
    • Sequence=AAF69622.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for RBP4 Gene

neXtProt entry for RBP4 Gene

Post-translational modifications for RBP4 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for RBP4 Gene

Antibodies for research

  • Abcam antibodies for RBP4

No data available for DME Specific Peptides for RBP4 Gene

Domains & Families for RBP4 Gene

Gene Families for RBP4 Gene

HGNC:
Human Protein Atlas (HPA):
  • Cancer-related genes
  • Disease related genes
  • Plasma proteins
  • Predicted intracellular proteins
  • Predicted secreted proteins

Protein Domains for RBP4 Gene

InterPro:
Blocks:
  • Lipocalin signature
  • Retinol binding protein signature

Suggested Antigen Peptide Sequences for RBP4 Gene

GenScript: Design optimal peptide antigens:
  • Plasma retinol-binding protein (RET4_HUMAN)

Graphical View of Domain Structure for InterPro Entry

P02753

UniProtKB/Swiss-Prot:

RET4_HUMAN :
  • Belongs to the calycin superfamily. Lipocalin family.
Family:
  • Belongs to the calycin superfamily. Lipocalin family.
genes like me logo Genes that share domains with RBP4: view

Function for RBP4 Gene

Molecular function for RBP4 Gene

UniProtKB/Swiss-Prot Function:
Retinol-binding protein that mediates retinol transport in blood plasma (PubMed:5541771). Delivers retinol from the liver stores to the peripheral tissues (Probable). Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane (PubMed:22665496).
GENATLAS Biochemistry:
retinol binding protein 4,serum (lipocalin family,Kernel group),monomer,binding to transthyretin

Phenotypes From GWAS Catalog for RBP4 Gene

Gene Ontology (GO) - Molecular Function for RBP4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005501 retinoid binding IEA --
GO:0005515 protein binding IPI 986177
GO:0016918 retinal binding IEA --
GO:0019841 retinol binding IEA,IDA 571335
GO:0034632 retinol transmembrane transporter activity IEA,IC 571335
genes like me logo Genes that share ontologies with RBP4: view
genes like me logo Genes that share phenotypes with RBP4: view

Human Phenotype Ontology for RBP4 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for RBP4 Gene

MGI Knock Outs for RBP4:
  • Rbp4 Rbp4<tm2Zhel>
  • Rbp4 Rbp4<tm1Gott>
  • Rbp4 Rbp4<tm1.1Mma>
  • Rbp4 Rbp4<tm1.1(KOMP)Vlcg>

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RBP4

No data available for Enzyme Numbers (IUBMB) , miRNA , Transcription Factor Targets and HOMER Transcription for RBP4 Gene

Localization for RBP4 Gene

Subcellular locations from UniProtKB/Swiss-Prot for RBP4 Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for RBP4 gene
Compartment Confidence
extracellular 5
cytosol 4
plasma membrane 2
mitochondrion 2
peroxisome 2
nucleus 2
endoplasmic reticulum 2
cytoskeleton 1
endosome 1
lysosome 1
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for RBP4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA,TAS --
GO:0005615 extracellular space IBA,ISS --
GO:0005829 cytosol TAS --
GO:0032991 protein-containing complex IEA --
GO:0070062 extracellular exosome HDA 19056867
genes like me logo Genes that share ontologies with RBP4: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for RBP4 Gene

Pathways & Interactions for RBP4 Gene

genes like me logo Genes that share pathways with RBP4: view

Gene Ontology (GO) - Biological Process for RBP4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001523 retinoid metabolic process TAS --
GO:0001654 eye development ISS --
GO:0002639 positive regulation of immunoglobulin production ISS --
GO:0006094 gluconeogenesis ISS --
GO:0007507 heart development ISS --
genes like me logo Genes that share ontologies with RBP4: view

No data available for SIGNOR curated interactions for RBP4 Gene

Drugs & Compounds for RBP4 Gene

(52) Drugs for RBP4 Gene - From: DrugBank, ClinicalTrials, ApexBio, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Vitamin A Approved, Vet_approved Nutra Carrier, binder 747
Beta carotene Approved Nutra Carrier, substrate 78
Tretinoin Approved, Investigational Nutra Target 288
2-[({4-[2-(trifluoromethyl)phenyl]piperidin-1-yl}carbonyl)amino]benzoic acid Experimental Pharma Carrier 0
N-Ethylretinamide Experimental Pharma Carrier 0

(32) Additional Compounds for RBP4 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs

(1) ApexBio Compounds for RBP4 Gene

Compound Action Cas Number
Vitamin A Acetate Unsaturated nutritional hydrocarbons 127-47-9
genes like me logo Genes that share compounds with RBP4: view

Transcripts for RBP4 Gene

mRNA/cDNA for RBP4 Gene

3 REFSEQ mRNAs :
5 NCBI additional mRNA sequence :
4 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RBP4

Alternative Splicing Database (ASD) splice patterns (SP) for RBP4 Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8 ^ 9
SP1: -
SP2: -
SP3: - -
SP4: - -
SP5:

Relevant External Links for RBP4 Gene

GeneLoc Exon Structure for
RBP4

Expression for RBP4 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for RBP4 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for RBP4 Gene

This gene is overexpressed in Liver (x41.7).

Protein differential expression in normal tissues from HIPED for RBP4 Gene

This gene is overexpressed in Serum (24.0), Synovial fluid (14.2), and Plasma (11.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for RBP4 Gene



Protein tissue co-expression partners for RBP4 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for RBP4

SOURCE GeneReport for Unigene cluster for RBP4 Gene:

Hs.50223

mRNA Expression by UniProt/SwissProt for RBP4 Gene:

P02753-RET4_HUMAN
Tissue specificity: Detected in blood plasma and in urine (at protein level).

Evidence on tissue expression from TISSUES for RBP4 Gene

  • Liver(4.9)
  • Pancreas(3.8)
  • Kidney(3.1)
  • Blood(2.7)
  • Heart(2.6)
  • Muscle(2.5)
  • Nervous system(2.5)
  • Intestine(2)
  • Eye(2)
  • Adrenal gland(2)

Phenotype-based relationships between genes and organs from Gene ORGANizer for RBP4 Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
Systems:
  • cardiovascular
  • digestive
  • integumentary
  • lymphatic
  • nervous
  • reproductive
  • respiratory
  • skeletal muscle
  • skeleton
  • urinary
Regions:
Head and neck:
  • brain
  • chin
  • cranial nerve
  • ear
  • eye
  • eyelid
  • face
  • head
  • jaw
  • mandible
  • maxilla
  • mouth
  • nose
  • skull
Thorax:
  • aorta
  • diaphragm
  • heart
  • heart valve
  • lung
Abdomen:
  • abdominal wall
  • intestine
  • kidney
  • large intestine
  • liver
  • small intestine
  • spleen
  • stomach
Pelvis:
  • testicle
  • ureter
  • uterus
General:
  • blood
  • blood vessel
  • peripheral nervous system
  • skin
genes like me logo Genes that share expression patterns with RBP4: view

Primer products for research

Orthologs for RBP4 Gene

This gene was present in the common ancestor of chordates.

Orthologs for RBP4 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia RBP4 29 30
  • 99.5 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia RBP4 29 30
  • 91.38 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia RBP4 29 30
  • 91.21 (n)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia RBP4 30
  • 88 (a)
OneToOne
Mouse
(Mus musculus)
Mammalia Rbp4 29 16 30
  • 85.24 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Rbp4 29
  • 84.74 (n)
Oppossum
(Monodelphis domestica)
Mammalia RBP4 30
  • 62 (a)
OneToOne
Chicken
(Gallus gallus)
Aves RBP4 29 30
  • 77.65 (n)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia RBP4 30
  • 60 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia rbp4 29
  • 65.74 (n)
African clawed frog
(Xenopus laevis)
Amphibia rbp4-prov 29
Zebrafish
(Danio rerio)
Actinopterygii rbp4 29 30
  • 65.71 (n)
OneToOne
Species where no ortholog for RBP4 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for RBP4 Gene

ENSEMBL:
Gene Tree for RBP4 (if available)
TreeFam:
Gene Tree for RBP4 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for RBP4: view image
Alliance of Genome Resources:
Additional Orthologs for RBP4

Paralogs for RBP4 Gene

No data available for Paralogs for RBP4 Gene

Variants for RBP4 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for RBP4 Gene

SNP ID Clinical significance and condition Chr 10 pos Variation AA Info Type
1002336 Uncertain Significance: not provided 93,594,003(-) C/T
NM_006744.4(RBP4):c.388G>A (p.Asp130Asn)
MISSENSE
1002349 Uncertain Significance: not provided 93,600,913(-) C/A
NM_006744.4(RBP4):c.111+5G>T
INTRON
1002888 Uncertain Significance: not provided 93,593,991(-) C/T
NM_006744.4(RBP4):c.400G>A (p.Val134Met)
MISSENSE
1013571 Likely Benign: not provided 93,593,832(-) C/T
NM_006744.4(RBP4):c.559G>A (p.Val187Ile)
MISSENSE
1017235 Uncertain Significance: not provided 93,593,824(-) G/A
NM_006744.4(RBP4):c.567C>T (p.Asn189=)
SYNONYMOUS

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for RBP4 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Variation tolerance for RBP4 Gene

Residual Variation Intolerance Score: 37.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.41; 9.06% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for RBP4 Gene

Human Gene Mutation Database (HGMD)
RBP4
SNPedia medical, phenotypic, and genealogical associations of SNPs for
RBP4
Leiden Open Variation Database (LOVD)
RBP4

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for RBP4 Gene

Disorders for RBP4 Gene

MalaCards: The human disease database

(41) MalaCards diseases for RBP4 Gene - From: OMI, CVR, GTR, ORP, SWI, COP, and GCD

- elite association - COSMIC cancer census association via MalaCards
Search RBP4 in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

RET4_HUMAN
  • Retinal dystrophy, iris coloboma, and comedogenic acne syndrome (RDCCAS) [MIM:615147]: A disease characterized by retinal degeneration, ocular colobomas involving both the anterior and posterior segment, impaired night vision and loss of visual acuity. Additional characteristic features include developmental abnormalities and severe acne. {ECO:0000269 PubMed:10232633, ECO:0000269 PubMed:23189188, ECO:0000269 PubMed:9888420}. Note=The disease is caused by variants affecting the gene represented in this entry. Loss of functional RBP4 protein results in serum retinol deficiency. Lack of normal levels of retinol impairs the visual cycle leading to night blindness at early stages; prolonged deficiency may lead to retinal degeneration. Additionally, retinol deficiency may result in dry skin, increased susceptibility to infection and acne (PubMed:23189188). {ECO:0000269 PubMed:23189188}.
  • Microphthalmia, isolated, with coloboma, 10 (MCOPCB10) [MIM:616428]: A disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues. Ocular abnormalities like opacities of the cornea and lens, scaring of the retina and choroid, and other abnormalities may also be present. Ocular colobomas are a set of malformations resulting from abnormal morphogenesis of the optic cup and stalk, and the fusion of the fetal fissure (optic fissure). {ECO:0000269 PubMed:25910211}. Note=The disease is caused by variants affecting the gene represented in this entry.

Genatlas disease for RBP4 Gene

night blindness and progressive atrophy of the retinal pigment epithelium,autosomal recessive,with retinol binding protein 4 deficiency

Additional Disease Information for RBP4

Human Genome Epidemiology Navigator
(HuGE)
Atlas
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
Open Targets Platform
genes like me logo Genes that share disorders with RBP4: view

Publications for RBP4 Gene

  1. Biochemical Basis for Dominant Inheritance, Variable Penetrance, and Maternal Effects in RBP4 Congenital Eye Disease. (PMID: 25910211) Chou CM … Glaser T (Cell 2015) 3 4 72
  2. Exome analysis identified a novel mutation in the RBP4 gene in a consanguineous pedigree with retinal dystrophy and developmental abnormalities. (PMID: 23189188) Cukras C … Ayyagari R (PloS one 2012) 3 4 72
  3. Regulatory SNP in the RBP4 gene modified the expression in adipocytes and associated with BMI. (PMID: 19851303) Munkhtulga L … Iwamoto S (Obesity (Silver Spring, Md.) 2010) 3 22 40
  4. Effect of RBP4 gene variants on circulating RBP4 concentration and type 2 diabetes in a Chinese population. (PMID: 18199128) Hu C … Xiang K (Diabetic medicine : a journal of the British Diabetic Association 2008) 3 22 40
  5. Retinol binding protein 4 as a candidate gene for type 2 diabetes and prediabetic intermediate traits. (PMID: 17174134) Craig RL … Elbein SC (Molecular genetics and metabolism 2007) 3 22 40

Products for RBP4 Gene

Sources for RBP4 Gene